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Alzheimer Conundrum : Entanglements of Dementia and Aging (Paperback) (Margaret Lock)

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Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer's disease through early detection of pre-symptomatic biological changes in healthy individuals.

Based on a meticulous account of the history of Alzheimer's disease and extensive in-depth interviews, the book highlights the limitations of biomarker detection. Margaret Lock argues that basic research must continue, but should be complemented by a public health approach to prevention that is economically feasible, more humane, and much more effective globally than one exclusively focused on an increasingly harried search for a cure.

"Thoughtful ... convincing. ... Margaret Lock is an extremely sharp critic of the Alzheimer's scene." ---W. F. Bynum, Times Literary Supplement

"For its wide scope and balanced critical evaluation an inspiring read for everyone working in the field." ---Eus Van Someren, Nature

"[The Alzheimer Conundrum] proves that the science of the disease is just as compelling as poignant accounts from caregivers and those suffering from Alzheimer's disease. Lock highlights just how much we don't know, from problems with Alzheimer's pathology, testing, and diagnosis to the search for a drug treatment ... While science plugs away at solving the Alzheimer's conundrum, Lock's call for improved care and social support takes on a new urgency." ---Publishers Weekly

"Comprehensive, cogent, and densely detailed, The Alzheimer Conundrum provides a useful antidote to media hype about `silver bullets' that are `just around the corner' and makes an important contribution to our understanding of an achingly tragic disease that touches virtually all of us." ---Glenn Altschuler, Psychology Today

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