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This new edition reviews the current status of both basic and applied research on the regulation of food intake. Its focus is on the use of new technologies and/or less common animal models explaining how they have advanced the understanding of appetitive and ingestive behavior. Sections examine novel animal models, advanced technologies facilitating progress, new understandings of central mechanisms, and central effects of nutrients on appetite. Chapters include the development of feeding circuits and various macronutrient effects on appetite.