Loading, please wait...

product description page

Aptamers Ligands : Powerful Tools from Molecular Evolution - (Hardcover)

Aptamers Ligands : Powerful Tools from Molecular Evolution -  (Hardcover) - image 1 of 1

About this item

The Aptamers Ligands: Powerful Tools from Molecular Evolution discusses these short, single strand oligonucleotides that can fold in a three-dimensional conformation and how they can provide a precise molecular recognition of a given target. These nucleic acid based ligands are identified from large naive combinatorial oligonucleotide libraries using a well-established technology called SELEX (systematic evolution of ligands by exponential enrichment). This approach inspired from the natural evolution concept where an expected evolutionary pressure allows the selection of ligands with very specific properties that can meet specification requirements unobtainable for antibodies or derived ligands.

Aptamers can be extremely specific towards their target molecule with high selectivity and proper affinity dissociation constants. Moreover, they can be selected to recognize a high diversity of molecules, from very small compounds, to large macromolecules, such as proteins.

  • Provides the molecular evolution of aptamers
  • Includes a technological history on the subject
  • Presents analytic and purification applications
Number of Pages: 200
Genre: Science
Format: Hardcover
Publisher: Textstream
Author: Gerald Perret & Frederic Duconge
Language: English
Street Date: December 1, 2018
TCIN: 53012735
UPC: 9781785482137
Item Number (DPCI): 248-51-8434
If the item details above aren’t accurate or complete, we want to know about it. Report incorrect product info.

Guest reviews

Prices, promotions, styles and availability may vary by store & online. See our price match guarantee. See how a store is chosen for you.