Breasst Epithelial Antigens - by Roberto Ceriani & International Workshop on Monoclonal Antibodies and Breast Cancer (Hardcover)

Book Synopsis

Session I.- Molecular Analysis of H23 Epithelial Tumor Antigen - Differentially Spliced Full Length cDNAs and Gene.- Characterization and Evolution of an Expressed Hypervariable Gene for Tumor-Associated Mucin, MUC-1.- Structure, Processing, Differential Glycosylation and Biology of Episialin.- Molecular Cloning and Expression of Breast Mucin-Associated Antigens.- Monoclonal Antibodies Reactive with Breast Cancer, Mammary Mucins and Synthetic Peptides.- Molecular Analysis of Epitopic Heterogeneity of the Breast Mucin.- Session II.- Expression and Prognostic Significance of the Her-2/NEU Oncogene During the Evolutionary Progression of Human Breast Cancer.- Structure and Function of MFG-E8: A Novel Apical Membrane Protein of Mouse Mammary Ephelial Cells.- Targeted Lysis of Human Breast Cancer Cells by Human Effector Cells Armed with Bispecific Antibody 2B1 (ANTI-c-erbB-2/ANTI-Fcy Receptor III).- Mechanisms Controlling Steroid Receptor Binding to Specific DNA Sequences.- Session III.- Origin and Nature of the Milk Lipid Globule Membrane.- N-Linked Oligosaccharide Synthesis and Cellular Sociology.- Development of Enzyme Immunoassays for Breast Carcinoma-Associated Mucin Antigens.- Clinical Studies and New Developments with Hybri-BREScan (CA-549), A Monoclonal Assay for Breast Cancer-Associated Antigen.- Evaluation of Several Tumor Markers (MCA, CA 15.3, BCM and CA 549) in Tissue and Serum of Patients with Breast Cancer.- IMx BCM: A Novel Monoclonal Based System for the Detection of Breast Cancer Associated Mucin.- A Novel Serum Assay Using Recombinant Breast Epithelial Mucin Antigen.- Session IV.- RadioimmunoguidedTM Surgery in Breast Cancer.- Immuno-Pharmacologic Purging of Breast Cancer from Bone Marrow.- Imaging, Pharmacokinetics, Dosimetry and Antitumor Effects of Radiolabeled Anti-Breast Cancer Antibodies in Mouse and Man.- Radioimmunotherapy with I-131 Chimeric L-6 in Advanced Breast Cancer.- Contributors.