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Comprehensive Analysis of Parasite Biology : From Metabolism to Drug Discovery (Hardcover)

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About this item

Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.
Number of Pages: 548
Genre: Medical
Series Title: Drug Discovery in Infectious Diseases
Format: Hardcover
Publisher: John Wiley & Sons Inc
Language: English
Street Date: October 10, 2016
TCIN: 51738299
UPC: 9783527339044
Item Number (DPCI): 248-30-5860
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