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Comprehensive Medicinal Chemistry (Hardcover)
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The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include for example drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification/validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery and the role of regulatory agencies in drug discovery. This new edition will provide a contemporary and forward looking critical analysis and summary of recent developments, emerging trends and recently identified new areas where medicinal chemistry impacts the topic.
- Comprehensively reviews the strategies, technologies, principles and applications of modern medicinal chemistry
- Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets
- Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs