Differin Adapalene Gel 0.1% Acne Treatment - 45g

Differin Adapalene Gel 0.1% Acne Treatment - 45g - image 1 of 4Differin Adapalene Gel 0.1% Acne Treatment - 45g - image 2 of 4Differin Adapalene Gel 0.1% Acne Treatment - 45g - image 3 of 4Differin Adapalene Gel 0.1% Acne Treatment - 45g - image 4 of 4
Differin Adapalene Gel 0.1% Acne Treatment - 45g - image 1 of 4
$33.49When purchased online

About this item

At a glance

HSA/FSA Eligible
HSA/FSA Eligible
Dermatologist Tested
Dermatologist Tested
Combination Skin
Combination Skin
Normal Skin
Normal Skin
Acne-Prone Skin
Acne-Prone Skin

Highlights

  • Once daily topical retinoid
  • First new, FDA-approved active ingredient to the OTC acne category in over 30 years
  • In clinical studies, Differin Gel provided nearly a 60% average reduction in acne lesions after 12 weeks which will continue to improve with further use
  • Clears redness and inflammation caused by acne
  • Prevents pimples, blackheads, whiteheads and clogged pores
  • Restores skin tone and texture by clearing acne
  • Oil free, fragrance free

Specifications

Scent: Unscented

Health Facts: Contains Retinoids

Product Form: Gel

Beauty Purpose: Spot Treatment

Recommended Skin Type: Normal, Acne-Prone, Combination

Net weight: 45 Grams

Features: Dermatologist Recommended, Dermatologist Tested

TCIN: 51346360
UPC: 302994920457
Item Number (DPCI): 037-12-0287
Origin: Assem USA w/foreign/dom. parts
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.

Description

Differin Gel is the FIRST and ONLY FDA-approved full prescription strength retinoid acne treatment now available without a prescription. Until now, 99% of all OTC acne medications in the US used only two different types of active ingredients. Differin Gel contains adapalene, a multi-benefit dermatologist recommended retinoid that clears and prevents acne which helps restore your skin's natural tone and texture. It is the newest active ingredient in OTC acne in over 30 years. Now you can clear your acne with the power of Rx.Directions:A 45 g tube of Differin can be used once a day, every day, up to a 90 day supply. A 15g tube of Differin can be used once a day, every day, up to a 30 day supply. 1. CLEANSE: Wash your face with a gentle, non-drying cleanser like Differin Balancing Cleanser.2. TREAT: Differin Gel is not used in the same way as a spot treatment. In order to get the best results,spread a thin layer over your face, once a day, every day. 3. MOISTURIZE: To help maintain healthy skin, use a moisturizer like Differin Balancing Moisturizer after each application. Use of a moisturizer may help decrease dryness and other signs of irritation..Ingredients:Active ingredient: Adapalene 0.1% (retinoid)Inactive ingredient: carbomer 940, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide. May contain hydrochloric acid to adjust pH.
HSA/FSA Eligible
Restrictions apply; contact your insurance provider about plan allowances and requirements
Dermatologist Tested
Dermatologist tested product.
Combination Skin
Recommended for Combination Skin.
Normal Skin
Recommended for Normal Skin.
Acne-Prone Skin
Recommended for Acne-Prone Skin.
If the item details above aren’t accurate or complete, we want to know about it.

Active ingredients

adapalene 0.1%

Purpose

Acne treatment

Uses

For the treatment of acne

Directions

Adults and children 12 years of age and older: use once daily clean the skin gently and pat dry before applying the product cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. do not use more than one time a day. Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age: ask a doctor

Other information

store at room temperature 680-77°F protect from freezing

Inactive ingredients

carbomer 940, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide. may contain hydrochloric acid to adjust ph.

Shipping details

Estimated ship dimensions: 1.54 inches length x 2.92 inches width x 7.25 inches height
Estimated ship weight: 0.15 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Q: Did it come with a seal on the top?

submitted by Kimberly B - 2 years ago
  • A: Hi Kimberly B! There is no seal on this product. Hope this helps.

    submitted byTarget Beauty Consulting - 1 year ago
    Brand expert
  • A: Hi Kimberly B - Differin Gel is packaged in the box, so the tube is not sealed. Hope this helps!

    submitted byGalderma Team Member - 1 year ago
    Brand expert

Q: What’s the different in the differen gel acne treatment ($29) vs the different gel acne ($12)?

submitted by Madison - 2 years ago
  • A: Hi Madison! The difference here is just the size of the product. The one closer to the $12 range is 15g whereas the larger one is 45g. Hope this helps!

    submitted byTarget Beauty Concierge - 2 years ago
    Brand expert
  • A: Container size only...

    submitted byLaura - 2 years ago

Q: Can I use this along with my Olay retinol 24 night cream?

submitted by Lezuk - 3 years ago
  • A: Hello Lezuk! Yes, you can. Hope this helps. - Virtual beauty concierge

    submitted byTarget Beauty Concierge - 3 years ago
    Brand expert
  • A: Hi there! I would suggest adding the Differin Adapalene Gel to your morning routine a few days a week to avoid over drying your skin. Don't forget to use sun protection also. Hope this helps!

    submitted byTarget Beauty Concierge - 3 years ago
    Brand expert

Q: Is this also Age Defense cream? What is Retinol strength?

submitted by Michele - 6 years ago
  • A: My dermatologist recommended Differin gel instead of wasting money on anti-aging creams and expensive skincare products.

    submitted byJat1012 - 2 years ago
  • A: Using this for anti-aging would be sort of an off label use. It's generally prescribed for acne. That being said it IS a retinoid and therefor can help reduce fine lines and wrinkles and can also smooth the appearance of skin overall. It helps even tone and smooth skin, it's an exfoliant. I used it "back in the day" for acne when it was prescription only and it didn't just clear the acne it made my skin better overall. It was a miracle for me. My skin went from acne and scaring everywhere to looking like perfect, clear, evenly toned skin with not a blemish or scar in sight. That was on young teenage skin. I'm now using it for my older skin but it's too early to tell if I will experience the miracle I did back then. Forewarned, this can and most likely will make your skin look worse before it looks better. Best thing is to stick with it and use it every single day and only use a very very thin layer.

    submitted byBeth - 6 years ago

Q: Do this product helps to clear acne scars? in how many days or months we can see the change?

submitted by Maharjan - 5 months ago
  • A: Patience is! Differin Gel treats acne deep in the pores and prevents new acne from forming, which restores skin’s texture and tone. Some people see results in as little as 2 weeks, though it may take up to 12 weeks for others. The longer you use Differin Gel, the better results you’ll see.

    submitted byGalderma Team Member - 5 months ago
    Brand expert

Q: Hi I am just 19 years old. I have bumpy forehead. I also have some acne and acne scars on my forehead and cheek bones. Can i use this product? Or can you plz suggest me the best one?

submitted by Maharjan - 5 months ago
  • A: Great question! For starters, Differin Gel contains the only OTC acne-fighting retinoid, adapalene. It’s the latest ingredient to shake up the acne aisle in more than 30 years. Differin Gel regulates skin cell turnover to prevent clogged pores, and acts as an anti-inflammatory agent to reduce acne, redness, and swelling. For acne scars, we would also recommend our new Resurfacing Scar Gel. It minimizes the appearance of post-acne scars — a top concern for adult acne sufferers — while visibly improving the appearance of rough, textured skin. Hope this helps!

    submitted byGalderma Team Member - 5 months ago
    Brand expert

Q: Is this product is authentic?

submitted by Iqra - 2 years ago
  • A: Hi Iqra! The Differin Adapalene Gel is authentic, hope this helps :)

    submitted byTarget Beauty Consulting - 1 year ago
    Brand expert

Q: my son use it once a day, it cleared most of his face but his nose has lot of pimples, what should he do?

submitted by mom3 - 2 years ago
  • A: Hi mom3! He may want to try combining this treatment with this daily face wash: Differin Daily Deep Cleanser with Benzoyl Peroxide. It can be used daily and really helps clear out pores. Hope this helps!

    submitted byTarget Beauty Concierge - 2 years ago
    Brand expert

Q: Is this safe to use while breastfeeding?

submitted by Anonymous - 2 years ago
  • A: It is not recommended to use this product while pregnant or breastfeeding. As always, ask your pharmacist or physician.

    submitted byAnonymous - 2 years ago

Q: Can you use this along with the dark spot corrector or just one?

submitted by - 2 years ago
  • A: Hi Karla! We recommend using Differin Adapalene Gel Acne Treatment to clear up your existing acne first. Then, the Differin Dark Spot Correcting Serum to heal any marks or scars. Hope this helps!

    submitted byTarget Beauty Concierge - 2 years ago
    Brand expert
4.7 out of 5 stars with 2499 reviews
90% would recommend
170 recommendations
Improves Skin Texture: 4.17 out of 5
Smoothens Skin: 4.06 out of 5
Treats Spots: 4.06 out of 5
Reduces Acne: 4.18 out of 5
Accurate Scent: 4.56 out of 5

Made my skin worse

1 out of 5 stars
Would not recommend
Kes - 1 month ago, Verified purchaser
Gave me cystic acne for a full 12 weeks until I finally quit using it.
Improves Skin Texture: 1 out of 5
Reduces Acne: 1 out of 5
Smoothens Skin: 1 out of 5
Accurate Scent: 5 out of 5
Treats Spots: 1 out of 5
Did you find this review helpful?

i love this product

5 out of 5 stars
nermeen16 - 2 months ago
originally posted on influenster.com
so i hopped onto the skin cracking trend from tiktok because i was seeing amazing results and nothing was working to maintain my stress breakout. i’ve been using this product on day 2: retinol for three weeks now and all i can say is i’m speechless. i didn’t expect this stuff to work so well. i usually see results just over night which is crazy! will definitely stick to this routine for the rest of me life.
7 guests found this review helpful. Did you?

Bye bye pimples

4 out of 5 stars
Would recommend
Bee - 2 months ago, Verified purchaser
Gets the job done. Dries face a little but with some lotion it's ok.
Accurate Scent: 3 out of 5
Smoothens Skin: 3 out of 5
Reduces Acne: 5 out of 5
Treats Spots: 3 out of 5
Improves Skin Texture: 4 out of 5
Did you find this review helpful?

The best!

5 out of 5 stars
Would recommend
SB - 2 months ago, Verified purchaser
This is one of the best OTC acne medications ever. I used it when I was younger when it was prescription only. It’s so good. It makes my skin look clearer and smoother. I recommend it to everyone!
Smoothens Skin: 5 out of 5
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
Reduces Acne: 5 out of 5
Improves Skin Texture: 5 out of 5
Did you find this review helpful?

Works!

5 out of 5 stars
Would recommend
Alinsa - 2 months ago, Verified purchaser
I never write reviews but I have extremely bad cystic acne and hormonal acne. Milk or cheese makes it a nightmare and sometimes I just can’t say no. But this is my holy grail! If you’re unsure about using this- don’t you need it! Just please don’t use with anything with alcohol or other chemicals and moisturizer and exfoliate. This is a lifetime commitment to this honestly but it’s worth it. I honestly wish they didn’t increase the price so much because it’s already expensive for a small amount and I’m on a budget but this is like a lifetime necessity for me.
Treats Spots: 5 out of 5
Accurate Scent: 5 out of 5
Reduces Acne: 5 out of 5
Improves Skin Texture: 5 out of 5
Smoothens Skin: 5 out of 5
1 guest found this review helpful. Did you?

A little goes a

4 out of 5 stars
nicoleh481 - 2 months ago
originally posted on influenster.com
A little goes a long way. Make sure you take recovery days for your skin because this stuff is powerful and as effective of a retinoid as its pricier counterparts. I wish I started using this stuff sooner. The texture is a little stickier than other retinoids but I don't mind it. It dries well and doesn't pill under moisturizer. Great product!
1 guest found this review helpful. Did you?

Good OTC acne med

5 out of 5 stars
Would recommend
Petey - 2 months ago, Verified purchaser
Cleared up my daughters acne
1 guest found this review helpful. Did you?

It's a miracle!

5 out of 5 stars
Avda - 2 months ago
originally posted on differin.com
Been using the gel 5 months. Suffered from adult painful cystic acne. After 1 month of nightly use 50% improvement, after 2 month 75% improvement, after 3 months 100% clear skin. I now use it every other night because it has also made the texture of my skin smooth as a baby's behind & the pores on my nose & face are a lot smaller. If I feel even one cyst starting I go back to every night application until it is gone. If you suffer from acne make the 3 month commitment to try it & don't give up!
16 guests found this review helpful. Did you?

One of the best over the counter

4 out of 5 stars
laurenm623 - 3 months ago
originally posted on influenster.com
This is one of the best over the counter treatments. I have hormonal acne and this helped. It does dry out your skin so make sure you moisturize it.
4 guests found this review helpful. Did you?

My go to

5 out of 5 stars
Nicole - 3 months ago, Verified purchaser
My holy grail. It can be very drying so make sure to keep your skin hydrated. Works wonders for acne!
2 guests found this review helpful. Did you?

Good

4 out of 5 stars
avag74 - 3 months ago
originally posted on influenster.com
Just started using this and on the first day I already notice a change to my acne. I’m hoping to use this more and I’m looking forward to clearing my skin up
3 guests found this review helpful. Did you?

Game changer

5 out of 5 stars
sommerr4 - 3 months ago
originally posted on influenster.com
This helped cleared my complexion within two months! I am super happy with the results it gave me, & this is going to become a staple in my skincare routine from now on. Give this a try!
7 guests found this review helpful. Did you?

Miracle

5 out of 5 stars
Would recommend
Sasha - 3 months ago
omg this helped me with my hormonal acne i am so relieved i could cry!
Treats Spots: 5 out of 5
Reduces Acne: 5 out of 5
Smoothens Skin: 5 out of 5
Improves Skin Texture: 5 out of 5
Accurate Scent: 5 out of 5
4 guests found this review helpful. Did you?

I feel like my

5 out of 5 stars
sarahchungmalmstrom - 3 months ago
originally posted on influenster.com
I feel like my skin is improved the morning after using it the previous night. I use a pea sized amount about twice a week, and I love that it helps with anti aging as well as my minor acne that pop up now and again. One tube lasts a long time and it spreads well also.
8 guests found this review helpful. Did you?

Differin Combo

5 out of 5 stars
vickyg46 - 3 months ago
originally posted on influenster.com
I use the Differin daily refreshing cleanser and then apply my Differin gel. I use a light moisturizer and this combo keeps breakouts minimal. I used to have to buy a membership to an expensive brand and I’m so thankful for Differins price and availability.
7 guests found this review helpful. Did you?

The best for stubborn acne

5 out of 5 stars
ashtonk2 - 4 months ago
originally posted on influenster.com
I love this product. It can be harsh. Definitely not for sensitive skin. Beats acne the best, even back acne. I highly recommend for anyone with recurring acne. Any Differin product rocks
9 guests found this review helpful. Did you?

Love

5 out of 5 stars
brandim105 - 4 months ago
originally posted on influenster.com
This differin gel is nothing short of Amazing when it comes to clearing acne. I have very sensitive oily skin and tend to get hormonal acne with occasional cystic acne. When I feel a pimple coming on I put some of the gel on it before bed and by morning it is already going away. This gel has saved me from actually getting a “pimple pimple” in over a year since I stumbled upon it. It has also helped my teenagers tame their breakouts. Fragrance free. Would repurchase
8 guests found this review helpful. Did you?

Good stuff

5 out of 5 stars
- 4 months ago
originally posted on influenster.com
Our family swears by Differin. Once our oldest saw a dermatologist to get his acne under control with lots of medications, we were able to use this instead. My daughter is now going through pop up acne and loves how quickly it works.
3 guests found this review helpful. Did you?

I love this product

5 out of 5 stars
yens5 - 4 months ago
originally posted on influenster.com
I have been using this product, this is the 2nd tube that I’m using now. I used the lot of stuff, they’re all expensive stuff but they didn’t help me with the acne. But DIFFERENT does help me a lot. My skin got a lot better now. I’m glad that I found it, I wish that I found it sooner.
2 guests found this review helpful. Did you?

love love

5 out of 5 stars
dizzyi - 4 months ago
originally posted on influenster.com
i use this once a day and only in the morning, i use it after i wash my face and put on my moisturizer. i love this product, but sometimes it gets sticky and doesnt dry out like it usually does.
2 guests found this review helpful. Did you?

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