$14.99 when purchased online
Target Online store #3991
About this item
Highlights
- TARGETS FACE AND BODY ACNE: Clear and prevent acne with the first FDA-approved prescription strength over-the-counter acne retinoid.
- OTC ACNE RETINOID: Differin Gel contains adapalene, the most effective skin acne retinoid treatment you can get without a prescription for consistently clearer skin.
- DERMATOLOGIST-RECOMMENDED: Doctors have prescribed adapalene gel to over 40 million people globally for more than 20 years.
- RESTORES TONE AND SKIN TEXTURE: Helps restore skin's natural tone and texture as a result of reduced acne.
- HOW TO USE: Apply once daily as part of a morning or evening skin care routine. After cleansing, apply a pea-sized amount all over the face. Follow with a moisturizer to decrease dryness or irritation and continue to use even when you're not breaking out.
- GREAT SIZED TRAVEL TOILETRIES: This product is under 3.4 fl oz, making it easy to take with you on your next vacation or trip.
Description
Differin Gel Acne Face and Body Treatment contains adapalene, an Rx-strength acne-fighting retinoid that helps clear breakouts where they start (works deep into pores in 5 minutes), helps prevents new acne from forming, and as a result, can restore skin's overall tone and texture. Adapalene is the first over-the-counter active ingredient for acne in more than 30 years. It clears acne with the power of an Rx without the prescription, prevents breakouts, blackheads, whiteheads, blemishes and clogged pores, and can be used to effectively treat acne. When used as directed, you could start to see results in as little as 1 week, and when used every single day, Differin Gel can help reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998, Galderma Laboratories).
Scent: Unscented
Trial/Mini/Travel Size: Yes
Health Facts: Phthalate-Free, No Fragrance Added, Aluminum-Free, Dye-Free, Contains Retinoids
Product Warning: Keep out of reach of children
Product Form: Gel
Disposability: Do not flush
Package Quantity: 1
Beauty Purpose: Combination, Spot Treatment, Skin Tone Improvement, Skin Texture Improvement, Damage Repair, Acne-Prone
Recommended Skin Type: Combination, Normal, Dry, Mature, Acne-Prone, Oily, Sensitive
Net weight: 15 Grams
Features: Dermatologist Tested, Skin Toning Agent, Dermatologist Recommended, Nongreasy
TCIN: 51346324
UPC: 302994920303
Item Number (DPCI): 037-12-0197
Origin: Assem USA w/foreign/dom. parts
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details above aren’t accurate or complete, we want to know about it.
Active ingredients
adapalene 0.1% (retinoid)* *read consumer information leaflet 0.1%
Purpose
Acne treatmentUses
Use For the treatment of acneDirections
Directions Adults and children 12 years of age and older: use once daily clean the skin gently and pat dry before applying the product cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. do not use more than one time a day. Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age: ask a doctorOther information
Other information store at room temperature 68°-77°F protect from freezingInactive ingredients
inactive ingredients carbomer 940, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide. may contain hydrochloric acid to adjust ph.
Shipping details
Estimated ship dimensions: 6.5 inches length x 2.625 inches width x 1.625 inches height
Estimated ship weight: 0.06 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
This product is featured in a recent Target Finds story
Best Acne Treatments Collection
About the collection
Create a skin-care regimen for acne-prone skin and find your best cleanser with our Best Acne Treatments Collection. This assortment contains everything you need to treat acne-prone skin and prevent breakouts, including deep-pore cleansing nose strips, face masks and benzoyl-peroxide acne medication. It also features the best face wash for acne, such as oil-free acne cleanser, facial scrub and cleansing balm, which work to dissolve makeup, dirt and oil without stripping moisture from your skin
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Summary of reviews
This product has received mixed reviews for its effectiveness in treating acne. Many guests have found it to be a game-changer for their skin, significantly reducing acne and improving skin texture. However, some guests with sensitive skin experienced irritation and chemical burns. Consistency and proper usage are key to achieving the best results.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.5 out of 5 stars with 2186 reviews
effectiveness: 4.33 out of 5
value: 4.24 out of 5
quality: 4.37 out of 5
84% would recommend
593 recommendations
Great for ingrown hairs
5 out of 5 stars
Thumbs up graphic, would recommend
CheriW - 11 days ago, Verified purchaser
The only product I've found to help with ingrown hairs.
Acne treatment
5 out of 5 stars
Thumbs up graphic, would recommend
SC - 12 days ago, Verified purchaser
My daughter loves this product. Works great for her.
Realistically Recommend
4 out of 5 stars
Thumbs up graphic, would recommend
HannahBM - 15 days ago, Verified purchaser
This product has improved my skin and I get more compliments on it now. I get some hormonal acne around my period which this makes no promises to prevent or treat. I was expecting a bit of a more radical change, but overall I like the product and it lasts a long time. I will be purchasing it again and view it as a critical part of my skincare routine now. I started using it the day I got it at the end of October 2024 and it is now January 2025, and I still have a good amount left. I have used a pea sized amount everyday and never had issues with dry skin, however, my eye patches that I used to like to use for self care (which contain retinol), I can no longer use because the skin is more sensitive. I would highly recommend if you are new to this type of product to both work your way up in frequency and hydrate your skin properly to avoid over drying and peeling. I have found that my eyes in general are more sensitive and have had to switch my sunscreen because of that even though I avoid the eye area when applying this product. I use a peptide serum with hyaluronic acid, snail mucin, vanicream, differin, then vanicream again (sandwich method) and a light oil on top. It’s not a “holy grail,” but no product is, but it is an effective and affordable synthetic retinol product. Below are pictures with a cc cream and one with no make up after my nightly skincare routine after about 6-7 weeks of use.
Works great if you cant get your hands on tretinoin
5 out of 5 stars
Thumbs up graphic, would recommend
Sufiya - 17 days ago, Verified purchaser
I really like Differin! I was using prescription tretinoin for 2 years but I had to stop due to insurance issues. I switched to using Differin and there was a bit of residual purging for a couple weeks during the transition but after that I think the daily use has been working to control my acne.
nightmare product
1 out of 5 stars
Thumbs down graphic, would not recommend
kaylux - 22 days ago
DO NOT USE with sensitive skin. I don’t even have sensitive skin and this made me purge for months. I used a tiny amount every 3 days mixed with moisturizer and the purge never ended from oct-may. Ruined my skin.
Highly effective for wrinkles and acne.
4 out of 5 stars
edc20_2831 - 1 month ago
originally posted on influenster.com
![](https://contentorigin.bazaarvoice.com/influenster/default/influenster.png)
Been using this for about a decade now, and it’s long been a staple in my skincare regimen. Highly effective against wrinkles and most kinds of acne. It’s lightweight, nonocclusive, and scentless, so it’s barely noticeable once rubbed in. It might be a bit pricey but goes a long way, so definitely worth it. The only downside side is that it is well known to cause skin dryness and sun sensitivity, so it’s best for nighttime use.
Goodbye acne breakouts!
5 out of 5 stars
oliviac269_3866 - 1 month ago
originally posted on influenster.com
![](https://contentorigin.bazaarvoice.com/influenster/default/influenster.png)
My dermatologist recommended Differing to help clear up acne & prevent breakouts, and I’d say this product has worked better than all others! It’s a lightweight gel that doesn’t irritate my sensitive skin, and within a day of applying it to a breakout area, my acne is dried up. It CAN make my skin a little dry, but I’ll take that if it means clear skin!
Its a no.. causes acne instead of cleaing away roughness and whiteheads.
1 out of 5 stars
Thumbs down graphic, would not recommend
aroemomma - 2 months ago, Verified purchaser
Not for sensitive skin. It dosnt burn but it does make my skin very dry and has caused me to get quite a few pimples. I used this to help with my white heads and texture. Just made me break out like a teenager.
Differin does works amazing.
5 out of 5 stars
jenalynq_799254 - 2 months ago
originally posted on influenster.com
![](https://contentorigin.bazaarvoice.com/influenster/default/influenster.png)
I have cystic acne and this helped me a lot! A little goes a long way. The product isn’t thick at all. Moisturize after using to avoid purging. Now my acne only lasts for 3 days. I’m so happy! It’s worth every penny.
I even have sensitive skin and it works for me
5 out of 5 stars
Herandhem40 - 2 months ago
originally posted on differin.com
I used to have horrible skin, and everything that I tried would never do anything except for make it worse. I would even go get facials trying to make my skin better. Then I found Differin. It has worked miracles on my skin.
Works well alone but better with adapelene
5 out of 5 stars
Thumbs up graphic, would recommend
CJDavis - 2 months ago
My skin is sensitive and I get acne from everything including monthly hormonal changes, food allergies and my work environment, etc. Lonnng sigh lol. I have used Kojie Acid Soap off & on for years and it worked but lately it seems to not be as effective especially on the allergies acne. I saw this and took a chance because of the price and I can find it anywhere in the country. I started using the adapelene gel at night. It was great but, it doesn’t work well on spot treatments so I added this one (benzoyl peroxide) in the daytime and that’s when I saw the biggest improvements in my acne and dark spots. I do still wash day and night with Kojie Acid. I only use my face cream in the daytime. I also started back dermaplaning once a month.
Finally, something that worked
5 out of 5 stars
HMathis - 3 months ago
originally posted on differin.com
This product was a Godsend for me. I am in my mid 20s and have not struggled with acne since I was in my early teens, but all of a sudden my skin started breaking out horribly with no apparent cause. I religiously used products containing salicylic acid & benzyl peroxide for months with no improvement whatsoever. My skin just got extremely dry and more red and irritated. I decided to switch things up and stumbled upon this product online. My skin started significantly clearing up after only about a week of use. Yes, I did go through retinization, and my face got very dry/red/flaky at first, but I quickly adjusted and have been using it every night since. I have been clear of breakouts for around 6 months aside from the very occasional 1 or 2 blemishes that still pop up here or there. My only complaint is that my skin is now extremely sensitive to the sun, and often feels like it's sunburnt when outside, even if the sun is not shining directly on it - and yes I am an avid sunscreen user. This sensation has lessened a bit over time, and isn't severe enough to make me stop using the product. I will always swear by it.
Use this and nothing else
5 out of 5 stars
Nor 22 - 3 months ago
originally posted on differin.com
Differin changed my life ! Best product for break out and acne
9 day difference
5 out of 5 stars
Thumbs up graphic, would recommend
Erickalynn - 3 months ago, Verified purchaser
Love how quickly you see results. My pores are smaller, and my face is clearing up.
Wait a little more
2 out of 5 stars
a - 3 months ago
So far I’ve been on it for exactly a month, my skin is dry. Very dry and new acne keeps showing up. My skin is really red now and pretty sensitive. I think I might take a break for a week and see how it goes. So far it’s not helping and it’s been making my acne worse than it was.
Ruined my Skin
1 out of 5 stars
Thumbs down graphic, would not recommend
Dani - 3 months ago
I have sensitive skin and this was recommended to me for my acne. I used it as directed for three weeks and it ruined my skin. At first it was fine but by week two my entire skin burned severely. Just splashing room temperature water on my face stings extremely bad now. Even my eye lids somehow became inflamed and the skin began to flake though I wasn’t applying the gel anywhere near them. I discontinued using the product and now I’m having to undergo a painful recovery process.
This saved my face
5 out of 5 stars
zonamakeup - 3 months ago
originally posted on influenster.com
![](https://contentorigin.bazaarvoice.com/influenster/default/influenster.png)
I can’t thank this product enough. When covid started and had to wear mask 12 hours a day on summer, my face suffered terrible breakouts and nothing solved but this. I rebought it again this summer because of some hormonal issues and my face is way better. I am sure I will buy it again next year
It really works!
4 out of 5 stars
maysono - 3 months ago
originally posted on influenster.com
![](https://contentorigin.bazaarvoice.com/influenster/default/influenster.png)
Wonderful product. Has helped clear up acne after using it for a few months. I like the pump bottle. It is easy to apply and you don’t need much! My skin was a little dry and sensitive at first, but now it’s working great for me! I use it after washing my face, underneath a good moisturizer.
Good for reg acne and pores, not as good with hormonal acne
3 out of 5 stars
Thumbs down graphic, would not recommend
Dr - 3 months ago, Verified purchaser
It's okay, it definitely helps me with blackheads but it barely helps with everything else. With combination skin, it dried me out a lot. I wouldn't recommend applying it everywhere, mostly for spot treatments, but it didn't work well with hormonal acne.
Differin ruined my eyelids.
1 out of 5 stars
Differin eye reaction - 4 months ago
originally posted on differin.com
I accidentally rubbed the smallest amount on my eye lid, and now the skin around my eyes is so sensitive. It’s been WEEKS and I can’t wear eyeshadow or eyeliner without it burning. I stopped the treatment over a month ago when I woke up with severely puffy, red eyes. I thought it was pink eye, it was so bad. I stopped use of the gel, applied hydrocortisone, and it got a little better. I finally started wearing a little bit of makeup, and my eyes are so swollen all over again. I hope this goes away, I had zero issues before I used this God forsaken gel.