About this item
This textbook introduces genetics and genomics and treats transmission genetics, molecular genetics, and evolutionary genetics as integrated subjects. It emphasizes genetics as an experimental approach and a field pertaining to genetic transmission, function, and mutation. It organizes chapters into sections on an overview of genes and genetic analysis, then transmission genetics, the organization and replication of DNA, gene expression and regulation, and evolutionary genetics. Revised and updated, this edition has been reorganized and has new sections on gene localization by association analysis, misconceptions about heritability, mobile DNA, Illumina sequencing, the Luria-Delbruck experiment, functional genomics, the use of RNAi for gene expression knockdown, Wolbachia transmission in arthropod species, molecular signals of selection, regulatory RNAs in development, and other topics; expanded coverage of RNA-seq, simple-sequence repeat variation for genotyping, the cis-trans test, the role of non-coding RNAs in regulation, whole-exome sequencing, cancer genomics, and ancient DNA analysis; rewritten boxes on classic papers; new boxes on recent research and developments in the field, such as the use of CRISPR-Cas9 for gene repair in muscular dystrophy; and new and revised illustrations. Included is access to an ebook and other online resources. Annotation ©2018 Ringgold, Inc., Portland, OR (protoview.com)
Number of Pages: 829
Publisher: Jones & Bartlett Learning
Author: Ph.D. Daniel L. Hartl & Ph.D. Bruce J. Cochrane
Street Date: November 30, 2017
Item Number (DPCI): 248-50-4766
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