While Ugo Ripamonti is listed as the editor of this volume, he is the author or co-author of all the papers collected here. The book summarizes his years of research into the role of the three mammalian transforming growth factor-beta protein isoforms in bone formation. Most research in the field has been with bone morphogenetic proteins. Rimpamonti's research was largely done with non-human primates. It looks at regeneration of craniofacial tissue, heterotopic tissue induction, periodontal tissue regeneration, and synergistic induction of bone formation. A concluding chapter looks at the possible future clinical role of the TGF-beta isoform in human studies. The book is well illustrated with black and white and color plates. Annotation ©2016 Ringgold, Inc., Portland, OR (protoview.com)
The effects of the bone morphogenetic protein family (BMP) of growth factors on bone formation are well documented, but the TGF-beta isoforms are much less studied and have the potential to shed light on the apparent redundancy of bone induction signalling. This edited book sums up the editor's 15 years of research into the osteogenic activity of the TGF-beta growth factor family, particularly in primates. The book awakens skeletal reconstructionists, tissue engineers, and molecular and cellular biologists to the profound and important bone inductive activity of the hTGF-ß3 isoform.
Number of Pages: 197
Sub-Genre: Life Sciences / Biology / Molecular Biology, Life Sciences / Cytology
Publisher: Taylor & Francis
Street Date: October 2, 2015
Item Number (DPCI): 247-50-8068