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Recent advances in genomics technology has dramatically reduced the cost of genome sequencing. Huge amounts of data is generated by next generation sequencing (NGS) technologies, posing substantial data analysis problems for many life scientists. There is a huge gap in this field for a book that gives practical guidance on these complex methods. This book does just that. It provides practical NGS data analysis techniques for an applied audience with guidance on software and algorithms. It includes lots of examples using real data to illustrate all the techniques. These features and more make it quite possibley the first pratical book on NGS data analysis with practical application.