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Polyamines in Fungi : Their Distribution, Metabolism, and Role in Cell Differentiation and Morphogenesis

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This book describes the contribution and potential use of fungi as models for the study of polyamines, in comparison to other organisms, examining the individual function of each polyamine; why they have high levels of regulation, including transport and back conversion; the role of spermine; and the basic mechanisms of function in all the roles they have in cells, including differentiation. It addresses the chemistry and cellular localization of polyamines; mechanisms of biosynthesis, their interconversion, and degradation in fungi, in comparison with animal and plant cells; polyamine distribution in the fungal kingdom as compared to other eukaryotic organisms; regulatory mechanisms of polyamine metabolism at the transcriptional, translational, and posttranslational levels in fungi and other organisms; general functions of polyamines, their possible modes of action, and their role in cell differentiation and morphogenesis in fungi and other organisms; and polyamine metabolism as a target for disease. Annotation ©2016 Ringgold, Inc., Portland, OR (

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