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Reactive Species Detection in Biology : From Fluorescence to Electron Paramagnetic Resonance
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Reactive oxygen species have been implicated in the pathogenesis of various diseases and therefore their detection and identification in biological systems is of extreme importance.Reactive Species Detection in Biology presents theories, chemistries, methodologies, and various applications for the detection of reactive species in biological systems, bothin-vitro and in-vivo. Techniques covered include fluorescence, high performance chromatography, mass spectrometry, immunochemistry, and electron paramagnetic resonance spectroscopy. Probe design and development are also reviewed in order to advance new approaches in radical detection either through synthesis, computations, or experimental applications.
- Reviews all current advances in radical detection
- Emphasizes chemical structures and reaction schemes fundamental to radical detection and identification
- Describes the uses, advantages, and disadvantages of various probe designs
- Examines new approaches to radical probe development