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Study of the Peptide-peptide & Peptide-protein Interactions and Their Applications in Cell Imaging and

Study of the Peptide-peptide & Peptide-protein Interactions and Their Applications in Cell Imaging and - image 1 of 1

About this item

This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.” This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.

Genre: Science, Technology
Series Title: Springer Theses
Format: Hardcover
Publisher: Springer Verlag
Author: Jianpeng Wang
Language: English
Street Date: October 28, 2016
TCIN: 51554063
UPC: 9783662533970
Item Number (DPCI): 248-24-0285
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