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Telomerase Revolution : The Enzyme That Holds the Key to Human Aging...and Will Soon Lead to Longer,

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Science is on the cusp of a revolutionary breakthrough. We now understand more about agingand how to prevent and reverse itthan ever before.In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extensioneven age reversalhas moved from science fiction to real possibility.Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. InThe Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging.Twenty years ago, there was still considerable debate of the nature of human aging, with a variety of competing theories in play. But scientific consensus is forming around the telomere theory of aging. The essence of this theory is that human aging is the result of cellular aging. Every time a cell reproduces, its telomeres (the tips of the chromosomes) shorten. With every shortening of the telomeres, the cell’s ability to repair its molecules decreases. It ages. Human aging is the result of the aging of the body’s trillions of cells.But some of our cells don’t age. Sex cells and stem cells can reproduce indefinitely, without aging, because they create telomerase. Telomerase re-lengthens the telomeres, keeping these cells young.The Telomerase Revolution describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to dramatically extend life spans and even reverse human aging. Telomerase-based treatments are already available, and have shown early promise, but much more potent treatments will become available over the next decade.The Telomerase Revolution is the definitive work on the latest science on human aging, covering both the theory and the clinical implications. It takes the reader to the forefront of the upcoming revolution in human medicine.
Science is on the cusp of a revolutionary breakthrough. We now understand more about agingand how to prevent and reverse itthan ever before.

In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extensioneven age reversalhas moved from science fiction to real possibility.

Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. InThe Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging.

On first examination, aging appears inevitable and straight-forward. Everything, after all, from mountains and galaxies, to plants and animals, ages, doesn?t it? Not exactly. With deeper consideration, aging turns out to be complex, and surprising questions emerge:

Is aging something that happens within our cells or in the organism as a whole?
Why do some cells age every time they reproduce, while others can reproduce indefinitely, without signs of aging?
How close are we to being able to dramatically extend life-spans and cure age-related diseases such as Alzheimer?s, dementia, and strokes?

Instead of the common idea that we accumulate damage, therefore we age,? the reality is the opposite: our cells age and so we begin to accumulate damage. The latest research shows so-called ageless? cells contain telomerase?an enzyme that maintains telomeres and adds back segments lost during replication. Essentially, it is the telomere that controls how well our cells repair themselves over time.

The Telomerase Revolution explains simply how we came to understand the ways aging and age-related diseases work, what we can do about them now, what we will be able to do to cure and prevent these diseasesand why we are now on the brink of a revolution in human medicine.
Number of Pages: 223
Genre: Science, Medical
Sub-Genre: Aging
Format: Hardcover
Publisher: Perseus Distribution Services
Author: Michael Fossel
Language: English
Street Date: October 6, 2015
TCIN: 46761190
UPC: 9781941631690
Item Number (DPCI): 247-51-6844
$21.20
MSRPReg: $24.95 Save $3.75 (15% off)

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