Sponsored
Timeless Skin Care Matrixyl Synthe'6 Serum
$25.99
In Stock
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At a glance
Sponsored
About this item
Highlights
- Restores firmness to the skin
- Stimulates collagen & elastin production
- Increases skin elasticity
- Diminishes pronounced fine lines & wrinkles
- Promotes optimal skin hydration levels
- Paraben & Sulfate Free
- Fragrance and Dye Free
- Made in the USA
- Cruelty Free - Leaping Bunny Certified
- More actives, less chemicals
Description
The Restorer - Help turn back time on the visible signs of aging with Matrixyl®️ synthe’6®️. With six critical skin-building essentials, this powerful polypeptide targets pronounced wrinkles and expression lines by stimulating collagen production. Along with the ultra-hydrating properties of Hyaluronic Acid, it helps tired, damaged skin, and treats pronounced wrinkles and sun damaged skin. Lifts and plumps to reveal firmer, younger-looking skin. Beneficial for skin on the neck and décolleté.
How it works: Timeless Skin Care's Matrixyl S6 contains a 2% concentration of Matrixyl®️ Synthe’6®️, a powerful polypeptide that promotes collagen production. This polypeptide stimulates six major constituents of the skin matrix and dermal-epidermal junction (collagen I, II, IV, fibronectin, hyaluronic acid, and lamin 5). Combined with Hyaluronic Acid for powerful hydration, this serum helps reverse the visible signs of aging and smooths out deep wrinkles and fine lines.
Recommended for: All skin types, especially dry and mature skin
Targets: Visible signs of aging, Wrinkles
Application: Use 2-3 drops onto clean skin and smooth with your fingertips. Wait until the product has fully absorbed into the skin before the next step in your routine.
Frequency: Use daily, PM use recommended for best results as skin cells are in a restorative mode while asleep.
How it works: Timeless Skin Care's Matrixyl S6 contains a 2% concentration of Matrixyl®️ Synthe’6®️, a powerful polypeptide that promotes collagen production. This polypeptide stimulates six major constituents of the skin matrix and dermal-epidermal junction (collagen I, II, IV, fibronectin, hyaluronic acid, and lamin 5). Combined with Hyaluronic Acid for powerful hydration, this serum helps reverse the visible signs of aging and smooths out deep wrinkles and fine lines.
Recommended for: All skin types, especially dry and mature skin
Targets: Visible signs of aging, Wrinkles
Application: Use 2-3 drops onto clean skin and smooth with your fingertips. Wait until the product has fully absorbed into the skin before the next step in your routine.
Frequency: Use daily, PM use recommended for best results as skin cells are in a restorative mode while asleep.
Scent: Unscented
Health Facts: Contains Hyaluronic Acid
Product Form: Serum
Sustainability Claims: Not Tested on Animals
Beauty Purpose: Wrinkle Reduction, Fine Line Reduction, Damage Repair, Firming, Hydrating
Recommended Skin Type: Mature, Dry
Net weight: 1 fl oz (US)
TCIN: 80184081
UPC: 858588004787
Item Number (DPCI): 037-12-7340
Origin: Made in the USA
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.
Ingredients:
water, matrixyl synthe'6, aloe, glycerin, hyaluronic acid, benzylalcohol dha.' '
Shipping details
Estimated ship dimensions: 4.3 inches length x 1.9 inches width x 1.8 inches height
Estimated ship weight: 0.166 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
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Guests are saying
This product has garnered positive feedback for its hydrating and anti-aging properties, making it a staple in many guests' skincare routines. Users appreciate its lightweight texture, quick absorption, and noticeable improvements in skin texture and appearance. Many guests have reported significant reductions in fine lines and wrinkles, making it a favorite among those seeking effective skincare solutions. Its compatibility with other products enhances its effectiveness, contributing to a youthful glow.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.9 out of 5 stars with 1661 reviews
effectiveness: 4.38 out of 5
quality: 4.87 out of 5
value: 4.8 out of 5
84% would recommend
13 recommendations
5 out of 5 stars
14 October, 2025
originally posted on https://www.timelessha.com/
Perfect serum
This product has been a staple in my face routine for two years now. It's super hydrating and soaks right into my skin, plumping it up. I think it's particularly helpful for those of us with oily combo skin that can't handle a heavy moisturizer/serum. I use this morning at night underneath my regular face moisturizer.
5 out of 5 stars
8 October, 2025
originally posted on https://www.timelessha.com/
Good peptides
Easy to use peptides
4 out of 5 stars
7 October, 2025
originally posted on https://www.timelessha.com/
Very nice!
I really like the softness after applying this product and letting it dry and applying my night moisturizer my skin is very soft! I haven't been using it long enough to see how it works for fine lines around my eyes and upper lip yet but I am enjoying how long the smoothness lasts.
5 out of 5 stars
Thumbs up graphic, would recommend
23 September, 2025Verified purchase
Great skincare product!
The timeless skin care line is an amazing, high quality, line of products that provides great results and makes my skin feel amazing. I use this in conjunction with the Vitamin C+E Ferulic Acid Cerum and the Q10 Serum. Incredibly happy with the results. A very simple, non-fussy routine.
5 out of 5 stars
Thumbs up graphic, would recommend
21 September, 2025Verified purchase
The best.
Perfect hydration, I put this on after toner and I just got a professional facial — she said I had some of the best skin she’d ever seen! Highly recommend. A bottle will last you ~3 months at least.
5 out of 5 stars
20 September, 2025
originally posted on https://www.timelessha.com/
Love it
Fantastic. Use it since 10 years.
5 out of 5 stars
17 September, 2025
originally posted on https://www.timelessha.com/
Love it
Price and quality are unbeatable - my new holy grail!
5 out of 5 stars
13 September, 2025
originally posted on https://www.timelessha.com/
Fabulous!
So good!
5 out of 5 stars
8 September, 2025
originally posted on https://www.timelessha.com/
The most hydrating serum
I use it twice a day and my skin feels so plumped and hydrated. At night I put one drop on my dry lips followed by a ceramide lip balm and rise my lips are soft.
5 out of 5 stars
3 September, 2025
originally posted on https://www.timelessha.com/
Very happy
With use, I noticed a reduction in fine lines and wrinkles, improved hydration, and skin elasticity
5 out of 5 stars
2 September, 2025
originally posted on https://www.timelessha.com/
Beautiful serum
Goes on smoothly and efficiently, not greasy or tacky. Plays well with moisturizer on top. Been using for 5 years,, my skin hasn't looked better!
5 out of 5 stars
29 August, 2025
originally posted on https://www.timelessha.com/
Nice lightweight peptide
Nice lightweight peptide
5 out of 5 stars
17 August, 2025
originally posted on https://www.timelessha.com/
Great serum
Love this product seems to be doing great job with my skin. Very happy will continue to purchase.
5 out of 5 stars
15 August, 2025
originally posted on https://www.timelessha.com/
Matrixyl Synthe's6 serum
Very good product. Only been using this product for 1 week. It is doing great things for my skin. Will order again.
5 out of 5 stars
2 August, 2025
originally posted on https://www.timelessha.com/
Matrixyl to the rescue!
Love how it makes my face feel. I use it at night.
5 out of 5 stars
31 July, 2025
originally posted on https://www.timelessha.com/
Such a smooth application
Very excited for this serum, the ingredients are excellent. It's probably too soon to tell results but first impression is that it's a great size bottle for the price and the serum absorbs quickly. Can't wait to see how it improves my skin. Derm recommended it to extend the life of my botox
5 out of 5 stars
29 July, 2025
originally posted on https://www.timelessha.com/
light weight and effective
I have not used a serum before, but this one is great. it is light weight, keeps my skin feeling moist, never dry. It goes on after my vitamin C but before my sunscreen. Makeup goes on over all and stays on..I would highly recommend
5 out of 5 stars
26 July, 2025
originally posted on https://www.timelessha.com/
Supple, youthful skin
This product is astounding! I'm 62 and never had skin products before . Just simple cheap moisturizers over the years . Matrixyl makes my skin appear smooth, supple and youthful again! Really game changer! Excellent product
5 out of 5 stars
26 July, 2025
originally posted on https://www.timelessha.com/
Love
This a long with the vitamin c serum gives my skin a nice glow in the morning. Skin in looking really healthy again.
5 out of 5 stars
23 July, 2025
originally posted on https://www.timelessha.com/
Clearwater skin at age 79
Hello everyone! I am 79, and please take a look at the clarity of my skin. I use nothing else but Tilekess products daily. Been using TIMELESS PRODUCTS for years. I use it on my face, arms and legs. Décembre 2024, I had surgery for Basel cell carcinome. It left a scar on my forehead, but not for long. This product has fades it.