Most office file boxes are built to hold letter-size paper and letter hanging folders; several models also accommodate legal-size files. Always check the product specifications to confirm which sizes a particular box supports.

Common portability features include built-in or cut-out handles, contoured or comfort-grip handles, and lightweight constructions. Many designs are described as easy to carry and stackable for transport and storage.

Many file boxes have a single main compartment, while others add internal organization such as in‑lid compartments, internal pockets, and specialty inserts. Examples noted in listings include passport mesh bags, card slots, USB/U-disk pockets, outer pockets, and dedicated main pockets for documents.

File boxes are made from a range of materials including polyester, various plastics (like polypropylene and clear plastic), steel or other metals, woven or fabric constructions, paper and cardboard, and—in some fire-resistant models—silicone-coated fiberglass.

Closures range from zippered, double-layer designs (some with combination locks) to hinged or flip-top lids. Many boxes use snap or tight-fit latches that can accept a small padlock or zip tie, while some models are open-top for quick access.

Styles include crate-style mesh boxes with built-in rails for hanging folders, clear plastic open-top organizers, hinged or flip-top lidded boxes, woven or linen-wrapped lidded cubes, and collapsible fabric-style organizers.