The goal is to be the first player to discard all your cards. You match cards from your hand to cards in the center by number; matching both number and color yields a bonus. When you have two cards left you must shout "DOS."
DOS allows players to discard to either of two discard piles (and in some plays to both). Players can also match two cards from their hand to a single center card to create larger, more dynamic plays.
Player counts vary across listings and include: 1–6 players, 2–4 players, 2–6 players, 2–10 players, and 4–6 players.
Suggested ages in the listings include 7 years and up, 8 years and up, and 14 years and up.
DOS is described as fast-paced, easy to learn, and family-friendly—well suited for game nights. Reviewers emphasize its accessibility and straightforward gameplay for families.
Some listings note a color-blind accessible deck that adds graphic symbols or icons on each card to help identify colors.