Labeling varies by product: some items are marked for users 12 years and older, one mouth rinse lists use from 2 years and up, and certain topical options are labeled for adults 18 years and older.

Several topical treatments include numbing agents such as benzocaine and cooling ingredients like menthol to provide temporary relief from pain and itching. Some formulas also describe disinfecting or cleansing properties for the affected area.

Advanced hydrocolloid patches (invisible cold sore bandages) are described: they maintain skin moisture, shield the sore from irritants, adhere for hours, and can be worn discreetly with makeup.