Yes. Some wheel-style pizza cutters are made to be ambidextrous, with removable wheels and ergonomic handles that work comfortably in either hand. When shopping, check the product details or images for removable wheels, ambidextrous or reversible handles, and descriptions that mention left/right-handed use.
Common options include handheld wheel cutters, large rocker (rocker-style) blades, dough roller dockers for prepping dough, and multifunction tools that combine a wheel with spatula or serving features (often described as 4-in-1 slicer/serving tools).
Blades and main construction are commonly stainless steel. Handles and nonblade components are often plastic or polypropylene and may feature ergonomic or soft-touch finishes for comfort.
Removable wheels or blades make cleaning easier and many are dishwasher-safe when detached. They also allow safer storage: some models include snap-on blade covers or hanging loops to protect the blade and prevent accidents.