One bottle of 24 Excedrin Migraine Caplets for Migraine Headache Relief
Migraine medicine that delivers effective migraine headache pain relief
Provides migraine relief, including migraine headache pain, sensitivity to light and sound, nausea
With acetaminophen and aspirin as pain relievers, and caffeine to enhance their analgesic effect
Delivers a powerful triple action formula with two pain fighters and an amplifier
HSA and FSA eligible item. Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details.
Description
Excedrin Migraine Caplets for Migraine Headache Relief work fast to combat migraine headache pain, making Excedrin Migraine the #1 neurologist recommended OTC treatment for migraines.* Available in convenient caplet form, this powerful migraine medicine delivers a specialized triple action formula containing two pain fighters and an amplifier. These Excedrin caplets combine aspirin and acetaminophen with caffeine to provide migraine relief, including migraine headache pain, sensitivity to light and sound, and nausea. For some, this migraine headache medicine starts relieving migraine pain in 30 minutes.
*Among OTC medicine for migraines IQVIA, Inc., 2018
Suggested Age: 12 Years and Up
Active Ingredient Strength Value: 250 Milligrams
Product Warning: Keep out of reach of children
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 24
TCIN: 80042645
UPC: 300672039248
Item Number (DPCI): 094-01-0043
Origin: Made in the USA and Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.
Allergy Alert: Aspirin may cause a severe allergic reaction which may include:
Allergy Alert: Aspirin may cause a severe allergic reaction which may include:: hives,facial swelling,asthma (wheezing),shock
Liver Warning: This product contains acetaminophen. Severe liver damage may occur if you take
Liver Warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 2 caplets in 24 hours, which is the maximum daily amount,with other drugs containing acetaminophen,3 or more alcoholic drinks every day while using this product
Stomach Bleeding Warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you
Stomach Bleeding Warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you: are age 60 or older,have had stomach ulcers or bleeding problems,take a blood thinning (anticoagulant) or steroid drug,take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others),have 3 or more alcoholic drinks every day while using this product,take more or for a longer time than directed
Do not use
Do not use : if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer,with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist
Ask a doctor before use if
Ask a doctor before use if: you have never had migraines diagnosed by a health professional,you have a headache that is different from your usual migraines,you have the worst headache of your life,you have fever and stiff neck,you have headaches beginning after or caused by head injury, exertion, coughing or bending,you experienced your first headache after the age of 50,you have daily headaches,you have a migraine so severe as to require bed rest,you have liver disease,stomach bleeding warning applies to you,you have a history of stomach problems, such as heartburn,you have high blood pressure, heart disease, liver cirrhosis, or kidney disease,you are taking a diuretic,you have asthma,you have problems or serious side effects from taking pain relievers or fever reducers,you have vomiting with your migraine headache
Ask a doctor or pharmacist before use if you are
Ask a doctor or pharmacist before use if you are: taking a prescription drug for:,diabetes,gout,arthritis,under a doctor's care for any serious condition,taking any other drug,taking any other product that contains aspirin, acetaminophen, or any other pain reliever/fever reducer
Stop use and ask a doctor if
Stop use and ask a doctor if : an allergic reaction occurs. Seek medical help right away,you experience any of the following signs of stomach bleeding: feel faint; vomit blood; have bloody or black stools; have stomach pain that does not get better,your migraine is not relieved or worsens after first dose,new or unexpected symptoms occur,ringing in the ears or loss of hearing occurs
Directions
Directions: Do not use more than directed.
Adults
Take 2 caplets with a glass of water. If symptoms persist or worsen, ask your doctor. Do not take more than 2 caplets in 24 hours, unless directed by a doctor.
Under 18 Years of Age
Ask a doctor.
Other information
Other Information: Store at controlled room temperature 20 degrees - 25 degrees C (68 degrees - 77 degrees F). Close cap tightly after use. Read all product information before using. Keep this box for important information.
Estimated ship dimensions: 2.99 inches length x 1.92 inches width x 1.81 inches height
Estimated ship weight: 0.08 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
A: Excedrin Migraine Caplets can be used till the last date of the month mentioned in the expiry date printed on the product pack. The quality of the product can only be guaranteed up to the expiry date when the product is stored in its original packaging and both used and stored according to the instructions on the product labeling.
Excedrin Migraine is a highly effective over-the-counter solution for migraine relief, praised for its fast-acting formula that combines acetaminophen, aspirin, and caffeine. Many guests report significant relief within 20 to 30 minutes of taking the caplets, making it a reliable choice for those who experience frequent migraines. The product is easy to swallow and portable, ensuring that guests can keep it on hand for when they need it most. Overall, it stands out as a trusted option for managing migraine symptoms effectively.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.7
4.7 out of 5 stars
5082 star ratings
4.7 out of 5 stars with 5082 reviews
quality
4.8 out of 5
quality: 4.83 out of 5
value
4.8 out of 5
value: 4.79 out of 5
96% would recommend
25 recommendations
5 out of 5 stars
13 August, 2026Verified purchase
(no review title)
Necessary for migraines
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommendWould recommend
9 August, 2026
(no review title)
This stuff works amazingly for my migraines!
quality
5.0 out of 5
quality: 5 out of 5
value
5.0 out of 5
value: 5 out of 5
Did you find this review helpful?
1 out of 5 stars
Thumbs down graphic, would not recommendWould not recommend
6 August, 2026Verified purchase
damaged and opened
item arrived opened and damaged
Audrey S
quality
1.0 out of 5
quality: 1 out of 5
value
1.0 out of 5
value: 1 out of 5
Did you find this review helpful?
5 out of 5 stars
4 June, 2026
originally posted on influenster.com
Best for Migraine Relief
Excedrin Migraine is my go to and never disappoints. I have experienced migraines since I was a kid, and this product has always consistently helped. It’s a powerful pain reliever from a trusted brand.
MeganC
Did you find this review helpful?
5 out of 5 stars
11 May, 2026
originally posted on influenster.com
Fast, Reliable Migraine Relief
I get migraines every so often, and Excedrine Migraine capsules are honestly one of the only over the counter meds that actually help me. When I feel one coming on, I take it right away, and I usually start feeling relief within 20-30 minutes. It's definitely something I keep on hand for migraine days.
AngelaB
1 guest found this review helpful. Did you?
5 out of 5 stars
21 April, 2026
originally posted on influenster.com
Works every time
My go to for migraine relief. Works every time, super quickly. I’ve tried other migraine products out there and nothing compares to this. Never go anywhere without this!
BrandiS
1 guest found this review helpful. Did you?
4 out of 5 stars
29 March, 2026
originally posted on influenster.com
Usually works
It usually works on my migraines. Be careful with overdosing. It's easy because migraines doesn't want to leave you that easy, right. Only medications working better I found is by doctors order.
MonikaH
1 guest found this review helpful. Did you?
5 out of 5 stars
25 March, 2026
originally posted on influenster.com
Fast relief
I’ve tried a lot of over-the-counter headache medicines, and Excedrin Migraine is honestly one of the most effective ones I’ve used for real migraine relief. It’s especially helpful when you take it early-right when you feel a migraine starting.
AnnaN
1 guest found this review helpful. Did you?
5 out of 5 stars
15 March, 2026
originally posted on influenster.com
Fast migraine relief
I cannot say enough good things about excedrin migraine. When a migraine hits, it can completely derail my day-but this product has been a game changer. The relief is incredibly fast and reliable.
KalynC
1 guest found this review helpful. Did you?
5 out of 5 stars
13 March, 2026
originally posted on influenster.com
Works well to relieve migraine pain
It starts to take effect relatively quickly and helps reduce both the headache and the sensitivity to light that usually accompanies migraines. The tablets are easy to take and the bottle is practical to carry. It is always good to follow the directions, but in my experience it has been a very effective option when a strong migraine appears.
LuisJ
1 guest found this review helpful. Did you?
5 out of 5 stars
7 March, 2026
originally posted on influenster.com
Recommended
Excedrin is perfect for migraine days 8 deal with heavy headeacge almost daily and this medicine save my day as soon as i take them is a must have will recomendes
DinaR
Did you find this review helpful?
5 out of 5 stars
6 March, 2026
originally posted on influenster.com
Fast-acting relief that knocks out migraine pain a
I recently tried Excedrin Migraine during one of my worst migraine attacks, and I was pleasantly surprised by how effective it was. I followed the recommended dosage of two caplets with a glass of water, and within about 30 minutes I started to feel the pounding in my head ease up. By the one-hour mark, the pain was almost completely gone, and I was able to go about my day without feeling groggy or out of it. The packaging is practical and easy to open, which is a relief when you’re already dealing with a migraine. The bright red label makes it easy to spot in the medicine cabinet. I also liked that the bottle clearly lists the ingredients—acetaminophen, aspirin, and caffeine—so I knew exactly what I was taking. Overall, my experience with Excedrin Migraine was very positive. It worked quickly, the instructions were clear, and it gave me real relief when I needed it most. I’ll definitely keep it on hand for future migraine flare-ups.
VahidaB
1 guest found this review helpful. Did you?
5 out of 5 stars
28 February, 2026
originally posted on Excederin
I pills favorite!!!
[This review was collected as part of a promotion.] Is an efective doctor is recommended over the counter migraine treatment with a proven safety profile. In clinical studies patients with moderate to severe migraines experienced effective relief with just one dose. Excedrin Migraine contains therapeutically active acetaminofén, aspirin, and caffeinne. Very portable package is very dark and easy Open.
LigiaVictoriaR
Did you find this review helpful?
5 out of 5 stars
23 February, 2026
originally posted on influenster.com
FAST RELIEF
I have dealt with migraines since a young age & excedrin is my go to. Its affordable & fast working with ingredients that are focused on fast relief.
TishaS
Did you find this review helpful?
5 out of 5 stars
21 February, 2026
originally posted on influenster.com
Good
This is the only medicine that works for my migraines . They are easy to swallow and work fast . You get plenty in the bottle for a reasonable price .
KirkD
Did you find this review helpful?
4 out of 5 stars
16 February, 2026
originally posted on influenster.com
My go to when a migraine tries me
This is one of the few pills that quickly gets me back on my feet when a migraine hits. It starts to work pretty quickly and I can feel it take that sharp throbbing feeling down to something that I can actually function through. I like that I don’t have to wait hours wondering if it’s going to help, it just does. It’s strong so I only take it when I need to and when I do, it’s a lifesaver. If you want to be able to stop migraines in its tracks, I recommend excedrin migraine.
TrishW
Did you find this review helpful?
5 out of 5 stars
16 February, 2026
originally posted on influenster.com
Excedrin Migraine Works!
I’ve used this product for quite a while now. It really minimizes my migraines. I can count on it to help when I really need it. It has a long storage time do I don’t worry about it going out of date. It’s a good value when the rest of your day counts on it.
KathleenK
Did you find this review helpful?
5 out of 5 stars
15 February, 2026
originally posted on Excederin
The go to for migraine relief
[This review was collected as part of a promotion.] This is my go to for migraine relief, just take a couple with enough water and wait for a little bit. Always reliable, I always trust it. No side effects at least for me
JoseR
Did you find this review helpful?
5 out of 5 stars
11 February, 2026
originally posted on influenster.com
Effective relief
Effective migraine medicine. As soon as I feel the pressure start Excedrin gives me the relief I need. I always keep some in hand. The packaging always stands out so it’s easy to find in stores.
jessicar2173_6995
Did you find this review helpful?
5 out of 5 stars
10 February, 2026
originally posted on Excederin
Works great on migraine
[This review was collected as part of a promotion.] This is a great medicine for migraine sufferers. This has helped me a lot. I take it at onset of my migraine and it helps makes the day manageable. This is a very reliable product.