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Nioxin System 1 Therapy Conditioner - 10.1 fl oz: For All Hair Types, Hair Regrowth, Liquid Form - 2 of 4Nioxin System 1 Therapy Conditioner - 10.1 fl oz: For All Hair Types, Hair Regrowth, Liquid Form - 3 of 4Nioxin System 1 Therapy Conditioner - 10.1 fl oz: For All Hair Types, Hair Regrowth, Liquid Form - 4 of 4
Nioxin System 1 Therapy Conditioner - 10.1 fl oz: For All Hair Types, Hair Regrowth, Liquid Form - 1 of 4

Nioxin System 1 Therapy Conditioner - 10.1 fl oz: For All Hair Types, Hair Regrowth, Liquid Form

$27.00 ($2.67/fluid ounce)

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At a glance

About this item

Highlights

  • Professional hair and scalp conditioner for natural hair with light thinning.
  • Adds thickness and fullness to natural hair with light thinning.
  • Strengthens hair resilience against damage and breakage.

Description

Nioxin Pro Clinical's System Kit 1 is designed for natural, untreated hair with light thinning. Clinically and dermatologically tested, this conditioner is designed to amplify hair texture and strengthen resilience, resulting in thicker, fuller hair.

Formulated with a powerful blend of niacinamide, biotin and caffeine to help nourish the hair root, stimulate hair follicles and strengthen the hair.

Nioxin System 1 Conditioner enhances scalp health by promoting a healthy environment for hair growth. Its lightweight, moisturizing formula contains ingredients that strengthen the hair against damage and breakage, while promoting a healthier scalp.

To use, apply a small amount of conditioner to wet hair after shampooing. Gently massage into the scalp and hair, focusing on areas of concern. Leave on for 1-3 minutes, then rinse thoroughly. For best results, use daily alongside the Nioxin System 1 Scalp + Hair Shampoo and Scalp + Hair Thickening Treatment.
Hair Type: All Hair Types
Product Form: Liquid
Beauty Purpose: Strengthening, Conditioning, Hair Regrowth, Thickening
TCIN: 83878397
UPC: 4064666338705
Item Number (DPCI): 063-00-8616
Origin: Imported
If the item details aren’t accurate or complete, we want to know about it.

Ingredients:

aqua/water/eau, cetyl alcohol, stearamidopropyl dimethylamine, stearyl alcohol, distearyldimonium chloride, mentha arvensis leaf oil, mentha piperita (peppermint) oil, hydroxyethylcellulose, phenoxyethanol, benzyl alcohol, cetearyl alcohol, glyceryl stearate, oleyl alcohol, propylene glycol, methylparaben, peg-2m, propylparaben, polysorbate 60, quaternium-80, edta, citric acid, limonene, camellia sinensis leaf extract, silica, cystine bis-pg-propyl silanetriol, disodium phosphate, niacinamide, panthenol, biotin, lecithin, tocopheryl acetate, citrus paradisi (grapefruit) peel extract, humulus lupulus (hops) flower extract, urtica dioica (nettle) leaf extract, sodium phosphate, bht, acer saccharum (sugar maple) extract, citrus limon (lemon) peel extract, saccharum officinarum/sugar cane extract/extrait de canne a sucre, vaccinium myrtillus leaf extract, faex extract/yeast extract/extrait de levure, citrus aurantium dulcis, (orange) fruit extract, sodium benzoate, potassium sorbate, maltodextrin, blue 1 (ci 42090), ethylparaben, butylparaben.

Shipping details

Estimated ship dimensions: 10 inches length x 3 inches width x 3 inches height
Estimated ship weight: 0.78 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Additional product information and recommendations

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4.3 out of 5 stars with 787 reviews
effectiveness: 5 out of 5
quality: 5 out of 5
value: 4 out of 5
100% would recommend
1 recommendations
5 out of 5 stars
19 June, 2026
originally posted on Nioxin
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Winner

[This review was collected as part of a promotion.] This conditioner, made my hair feel so shiny, strong, yet full of volume. It was easy to dispense the conditioner, and I did not feel like there was buildup, which can happen pretty easily from conditioner. My hair definitely felt stronger and more durable which is what I need.
DD06
Did you find this review helpful?
5 out of 5 stars
17 June, 2026
originally posted on Nioxin
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Love!

[This review was collected as part of a promotion.] A lot goes a long way. It leaves my hair feeling soft but bouncy and not greasy at all. The scent is very mild. Love this conditioner, Just not the price.
BethanyB
Did you find this review helpful?
5 out of 5 stars
16 June, 2026
originally posted on Nioxin
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Texture light

[This review was collected as part of a promotion.] I’ve been using this conditioner after the shampoo from the same line. It’s texture is light, not too thick, and easy to apply. Most conditioners say not to apply them the scalp, but this one is different it’s recommended to apply it from the scalp to the ends. It easily and doesn’t leave any residue or greasy.
BlancaH
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5 out of 5 stars
11 June, 2026
originally posted on Nioxin
Image

Love

[This review was collected as part of a promotion.] I absolutely love this conditioner! It s definitely salon quality! I had my hair stylist use it on me. The smell is wonderful and it made my hair feel like silk. No tangles. She rinsed in cool water. My hair felt great
AstriaM
Did you find this review helpful?
4 out of 5 stars
7 June, 2026
originally posted on Nioxin
Image

A nice mild conditioner

[This review was collected as part of a promotion.] The Nioxin Age Defense Conditioner is a nice mild conditioner. It leaves my hair soft and easy to manage. The conditioner rinses out easily and doesn’t leave any residue. The scent is a nice almost minty one, not overwhelming. I received this product free in exchange for my honest review.
BethanyS
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1 out of 5 stars
3 June, 2026
originally posted on Nioxin
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Has DRYING Isopropyl Alcohol

I found this conditioner to be quite ineffective. My hair is super dry and frizzy after using it. I don't know how I missed the listing of Isopropyl Alcohol in the ingredient listing, but I am attributing the lackluster results I get with this conditioner to that VERY ingredient. My hair is better WITHOUT this conditioner.
Jeff
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3 out of 5 stars
24 May, 2026
originally posted on Nioxin
Image

It’s okay

[This review was collected as part of a promotion.] I am not a fan of the scent, and this is not the most moisturizing or efficient hair product but it helped make my hair a little softer. Not sure about the age defense part as I still see new white hairs coming in. Overall a normal conditioner, nothing special.
AndressaK
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3 out of 5 stars
18 May, 2026
originally posted on Nioxin
Image

Nothing special

[This review was collected as part of a promotion.] It’s okay I like the light clean scent and it deranges my hair and isn’t too heavy. But I don’t think it’s a must have. Really just basic so I have nothing really to say
MakinnaS
Did you find this review helpful?
5 out of 5 stars
14 May, 2026
originally posted on Nioxin
Image

The best conditioner I’ve used and had great resul

[This review was collected as part of a promotion.] The Nioxin Age Defense Conditioner is one of my favorite products from Nioxin’s new line. I have had great hair growth results from using this conditioner. My hat was breaking off all this time and I haven’t noticed any breakage lately. My hair isn’t tangled all the time and I do not have to bush it as often. My hair lays flat straight no flyaways and my hair looks healthy. This conditioner has truly hydrated my hair and helped change the texture of my hair for the better. The smell of this conditioner is absolutely amazing. If they sold the smell as a fragrance, I would definitely buy it in a heartbeat. This conditioner smells clean and fresh almost like a high-end luxury brand smell. I smell my hair all day long after I wash it because I love the smell of this product that much. If you have not tried this product, I highly recommend you do.
AmandaBellaG
Did you find this review helpful?
5 out of 5 stars
13 May, 2026
originally posted on Nioxin
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Sleek frizz free hair

[This review was collected as part of a promotion.] I received this product complementary exchange for my honest review. I really enjoyed trying the Nioxin age defense conditioner. I enjoyed the scent and how it left my hair looking sleek and frizz free. The packaging is nice but fairly standard. Overall I would recommend
CandiceS
Did you find this review helpful?
4 out of 5 stars
8 May, 2026
originally posted on Nioxin
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Good

[This review was collected as part of a promotion.] I like that the came in a set. Made my hair feel very nice. No frizz. Hair felt soft and was not tangled. Rinses out nicely. Not oily. Not overly thick.
DanielleM
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5 out of 5 stars
7 May, 2026
originally posted on Nioxin
Image

Love the softness

[This review was collected as part of a promotion.] This conditioner does a great job at leaving your hair feeling healthy and soft. It’s a nice consistency. It also helps with shine. Combined with the shampoo it’s a great system.
CrystalZ
Did you find this review helpful?
5 out of 5 stars
7 May, 2026
originally posted on Nioxin
Image

I love this

[This review was collected as part of a promotion.] I love this conditioner. Normal conditioners i would not use on my scalp, as it would weigh down my hair and leave an oily residue. This one is super light, but moisturizing enough for my dry ends.
ManJ
Did you find this review helpful?
5 out of 5 stars
5 May, 2026
originally posted on Nioxin
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Conditioner

[This review was collected as part of a promotion.] This is a pretty decent lightweight conditioner that worked well with my other curl products (for reference, I have 2A/2B waves). It was easy to apply and rinses off easily. Good clean scent.
TiffanyC
Did you find this review helpful?
3 out of 5 stars
5 May, 2026
originally posted on Nioxin
Image

Gets the job done

[This review was collected as part of a promotion.] I was skeptical about the instructions when I read to add conditioner on my entire hair because I thought it would get oily. I was wrong. It left my hair smooth and shinny. It was very easy to detangle and my hair smelled amazing.
EmilyR
Did you find this review helpful?
5 out of 5 stars
4 May, 2026
originally posted on Nioxin
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Age defense

[This review was collected as part of a promotion.] This stuff is great. A little bit goes a long way. The consistency is nice and helps derange my hair while in the shower. It makes my hair feel very moisturized.
JessicaG
Did you find this review helpful?
4 out of 5 stars
2 May, 2026
originally posted on Nioxin
Image

Soft hair

[This review was collected as part of a promotion.] This conditioner helped moisturize my hair and smells pleasant. I feel like it did help with my frizz. It leaves my hair soft, shiny and healthy.
AutumnB
Did you find this review helpful?
4 out of 5 stars
2 May, 2026
originally posted on Nioxin
Image

Great conditioner!

[This review was collected as part of a promotion.] Since using this system my grays have came back so much slower! I was skeptical at first but I am truly blown away. I also noticed you don’t need a ton of product which helped it last! I am really blown away by nioxin and plan to keep using the system in the future! Also I love the color of the packaging gives it a sleek look!
FayW
Did you find this review helpful?
4 out of 5 stars
2 May, 2026
originally posted on Nioxin
Image

Nice but takes a lot of product

[This review was collected as part of a promotion.] Works well but takes a lot of product to detangle my hair after shampooing. I’m going through the conditioner compared to the shampoo quicker than usual. My hair looks good, but I probably won’t rebuy.
MeganS
Did you find this review helpful?
5 out of 5 stars
30 April, 2026
originally posted on Nioxin
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Love it

[This review was collected as part of a promotion.] This conditioner has been heavenly for my dull, limp hair. After a few uses, my hair is shiny, bouncy and hydrated. My scalp feels really clean. I find a small amount goes a long way, and penetrates well into hair follicles! Easy to rinse and doesn’t leave hair feeling greasy.
NecheY
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