The Physiology and Pathophysiology of Muscle - by Gilbert Combs (Hardcover)

About the Book

Muscle physiology involves the mechanisms of muscle function, including contraction and relaxation. Skeletal muscles are composed of fibers containing actin and myosin filaments, which slide past each other to produce movement in response to neural stimulation. This process, as described by the sliding filament theory, is powered by ATP and regulated by calcium ions. Muscle performance is influenced by factors like fiber type, energy supply, and neural input. Pathophysiology of muscle comprise disorders that impair muscle function. Conditions like muscular dystrophies, myopathies, and inflammatory diseases disrupt normal muscle structure and function, leading to weakness, fatigue, and atrophy. Neuromuscular diseases, such as Amyotrophic Lateral Sclerosis (ALS), affect the nerves that control muscles, resulting in progressive muscle degeneration. Understanding these physiological and pathological mechanisms is crucial for developing treatments and interventions to maintain muscle health and function. This book elucidates the concepts and innovative models around prospective developments with respect to muscle physiology and pathophysiology. Most of the topics introduced in this book cover novel findings in the field of muscle movement. The extensive content of this book provides the readers with a thorough understanding of the subject.

Book Synopsis

Muscle physiology involves the mechanisms of muscle function, including contraction and relaxation. Skeletal muscles are composed of fibers containing actin and myosin filaments, which slide past each other to produce movement in response to neural stimulation. This process, as described by the sliding filament theory, is powered by ATP and regulated by calcium ions. Muscle performance is influenced by factors like fiber type, energy supply, and neural input. Pathophysiology of muscle comprise disorders that impair muscle function. Conditions like muscular dystrophies, myopathies, and inflammatory diseases disrupt normal muscle structure and function, leading to weakness, fatigue, and atrophy. Neuromuscular diseases, such as Amyotrophic Lateral Sclerosis (ALS), affect the nerves that control muscles, resulting in progressive muscle degeneration. Understanding these physiological and pathological mechanisms is crucial for developing treatments and interventions to maintain muscle health and function. This book elucidates the concepts and innovative models around prospective developments with respect to muscle physiology and pathophysiology. Most of the topics introduced in this book cover novel findings in the field of muscle movement. The extensive content of this book provides the readers with a thorough understanding of the subject.