Autoimmune Disorders - by Abdulla Watad & Nicola Luigi Bragazzi & Yehuda Shoenfeld (Hardcover)

About the Book

"Autoimmune disease occurs when an immune response attacks our own tissues. Like all adaptive immune responses, it is focused on specific antigens by T-cell receptors and B-cell receptors. In contrast to infection, the antigens that these cells recognise are processed from proteins within the target organ and this drives a chronic inflammatory process that disrupts the normal function of the tissue. In human diseases the trigger for this process cannot usually be determined. There is evidence that autoimmunity can follow infection, but that more than one infection can initiate disease. Other environmental factors are also relevant but are not well defined"--

Book Synopsis

Autoimmune Disorders

Comprehensive resource on the science of autoimmune disorders, covering causes, treatment, prevention, and the latest research in the field

Autoimmune Disorders is an authoritative reference on the science of autoimmune disorders, covering their causes, including infections, vaccine adjuvants, environmental stimuli, and silicone implants, the latest research on the genetics, epigenetics, and immunology of autoimmunity, predictive markers, therapeutic approaches for treatment and prevention, and suggestions for future research directions.

This book explores the intricate connections between adjuvants and autoimmune responses, focusing on the emergence of the Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA syndrome), as well as autoimmune connections in areas such as chronic fatigue syndrome, autoantibodies targeting the autonomic system, and small fiber neuropathy. The authors emphasize the profound impact of vaccines on public health, underscoring that their benefits far outweigh potential side effects and exploring the historical context of adjuvants in vaccine development. From tattoos to environmental factors, each chapter adds a unique thread to the tapestry of adjuvants, autoimmune responses, and their interactions.

Sample topics covered in Autoimmune Disorders include:

• Food additives and dental implants as a trigger of autoimmunity and increased risk of ASIA syndrome as a result of the chemical and social factors
• Sustained immune activation in ASIA syndrome as a bridge to lymphomagenesis and how immune checkpoints, metals, and bisphenol connect to autoimmunity
• Postural Orthostatic Tachycardia syndrome (POTS), Sick Building syndrome, and Gulf War syndrome (GWS) as parts of ASIA syndrome
• Sarcoidosis and Sjögren's syndrome as a proof of concept of hyperstimulation syndrome

Autoimmune Disorders is an essential reference on the subject for academics, specialized postgraduate students, and practicing professionals seeking to improve integrated research strategies and foster a deeper understanding of the complex relationship between immunology, public health, and individual well-being.

From the Back Cover

Comprehensive resource on the science of autoimmune disorders, covering causes, treatment, prevention, and the latest research in the field

Autoimmune Disorders is an authoritative reference on the science of autoimmune disorders, covering their causes, including infections, vaccine adjuvants, environmental stimuli, and silicone implants, the latest research on the genetics, epigenetics, and immunology of autoimmunity, predictive markers, therapeutic approaches for treatment and prevention, and suggestions for future research directions.

This book explores the intricate connections between adjuvants and autoimmune responses, focusing on the emergence of the Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA syndrome), as well as autoimmune connections in areas such as chronic fatigue syndrome, autoantibodies targeting the autonomic system, and small fiber neuropathy. The authors emphasize the profound impact of vaccines on public health, underscoring that their benefits far outweigh potential side effects and exploring the historical context of adjuvants in vaccine development. From tattoos to environmental factors, each chapter adds a unique thread to the tapestry of adjuvants, autoimmune responses, and their interactions.

Sample topics covered in Autoimmune Disorders include:

• Food additives and dental implants as a trigger of autoimmunity and increased risk of ASIA syndrome as a result of the chemical and social factors
• Sustained immune activation in ASIA syndrome as a bridge to lymphomagenesis and how immune checkpoints, metals, and bisphenol connect to autoimmunity
• Postural Orthostatic Tachycardia syndrome (POTS), Sick Building syndrome, and Gulf War syndrome (GWS) as parts of ASIA syndrome
• Sarcoidosis and Sjögren's syndrome as a proof of concept of hyperstimulation syndrome

Autoimmune Disorders is an essential reference on the subject for academics, specialized postgraduate students, and practicing professionals seeking to improve integrated research strategies and foster a deeper understanding of the complex relationship between immunology, public health, and individual well-being.

About the Author

Abdulla Watad is a specialist in Internal Medicine and Rheumatology at the Sheba Medical Center affiliated with the Tel Aviv University in Israel and a visiting researcher in rheumatology at Leeds University, UK.

Nicola Luigi Bragazzi, MD, PhD, is a specialist in public health, biophysics, and immunology, and is included in the ISI/Clarivate 2023 list of Highly Cited Researchers, as one of the 1% of the world's top influential researchers and scientists.

Yehuda Shoenfeld is a leader in the field of autoimmunity and founder and head of the Zabludowicz Center for Autoimmune Diseases in the Sheba Medical Center. He is affiliated with the Reichman University, Herzliya, Israel. His h-index is over 130 and he is an author of over 2000 scientific articles and many textbooks in autoimmunity.