Innovations in Antiviral Development and the Detection of Virus Infection - (NATO Asi Series) (Hardcover)

Book Synopsis

Studies of Reovirus Pathogenesis Reveal Potential Sites for Antiviral Intervention.- Drugs as Molecular Tools.- Genetically Engineered Bacteria to Identify and Produce Antiviral Agents.- Antiviral Agents from Novel Marine and Terrestrial Sources.- Virus Receptors: The Achilles' Heel of Human Rhinoviruses.- Therapeutic Strategies Employing CD4, The HIV Receptor.- Molecular Characterization of HIV-2 (ROD) Protease following PCR Cloning from Virus Infected H9 Cells.- A Novel, Non-Nucleoside Inhibitor of HIV-1 Reverse Transcriptase (Review).- Catalytic Antisense RNA (Ribozymes): Their Potential and Use as Anti-HIV-1 Therapeutic Agents.- Therapies for Hepatitis B Virus: Current Status and Future Possiblities.- A Preliminary Report of a Controlled Study of Thymosin Alpha-1 in the Woodchuck Model of Hepadnavirus Infection.- Delta Virus as a Vector for the Delivery of Biologically Active RNAs: Possibly a Ribozyme Specific for Chronic Hepatitis B Virus Infection.- Inhibition of Herpes Simplex Virus Ribonucleotide Reductase by Synthetic Nonapeptides: A Potential Antiviral Therapy.- Antiviral Effects of Herpes Simplex Virus Specific Anti-Sense Nucleic Acids.- Heterogeneity of a Herpes Simplex Virus Clinical Isolate Exhibiting Resistance to Acyclovir and Foscarnet.- Cellular Metabolism and Enzymatic Phosphorylation of 9-(2-Phosphonylmethoxyethyl) Guanine (PMEG), a Potential Antiviral Agent.- Effect of Herpes Simplex Virus Type 1 Infection on Cytokine Gene Expression in Activated Murine Peritoneal Macrophages.- Procedure for Evaluation of Neutralizing Antibody to Cytomegalovirus in Commercial Intravenous Gamma Globulin Preparations.- Improved Detection of Antibodies to Hepatitis C Virus Using a Second Generation ELISA.- Emerging Trends in the Rapid Detection of Viruses.- DNA Probes for Viral Diagnosis.- Contributors.