Pharmacokinetics and Metabolism in Drug Design - by Erica Helmer (Hardcover)
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About this item
Highlights
- Pharmacokinetics (PK) determines the outcome of substances which are administered in the human body and involves drug absorption, distribution, metabolism, and excretion (ADME) processes.
- Author(s): Erica Helmer
- 244 Pages
- Medical, Pharmacology
Description
About the Book
Pharmacokinetics (PK) determines the outcome of substances which are administered in the human body and involves drug absorption, distribution, metabolism, and excretion (ADME) processes. Drug absorption is the movement of drug in the bloodstream from its site of administration. It depends on multiple factors, including the formulation and chemical properties of a drug, drug-food interactions and route of administration. Drug distribution is essential for determining drug efficacy and drug toxicity. Drug metabolism is the chemical alteration of the drug by the body. Genetics, age and drug interactions are some factors that affect drug metabolism. In clinical use, an enzyme named cytochrome P450 (CYP450) is responsible for the biotransformation or metabolism of all drugs. It is essential to comprehend the basic mechanisms governing the pharmacokinetics of a drug for designing personalized course of therapy for patients. This book provides comprehensive insights into the role of pharmacokinetics and metabolism in drug design. It is appropriate for students seeking detailed information in this area of study as well as for experts.Book Synopsis
Pharmacokinetics (PK) determines the outcome of substances which are administered in the human body and involves drug absorption, distribution, metabolism, and excretion (ADME) processes. Drug absorption is the movement of drug in the bloodstream from its site of administration. It depends on multiple factors, including the formulation and chemical properties of a drug, drug-food interactions and route of administration. Drug distribution is essential for determining drug efficacy and drug toxicity. Drug metabolism is the chemical alteration of the drug by the body. Genetics, age and drug interactions are some factors that affect drug metabolism. In clinical use, an enzyme named cytochrome P450 (CYP450) is responsible for the biotransformation or metabolism of all drugs. It is essential to comprehend the basic mechanisms governing the pharmacokinetics of a drug for designing personalized course of therapy for patients. This book provides comprehensive insights into the role of pharmacokinetics and metabolism in drug design. It is appropriate for students seeking detailed information in this area of study as well as for experts.Dimensions (Overall): 11.0 Inches (H) x 8.5 Inches (W) x .63 Inches (D)
Weight: 1.9 Pounds
Suggested Age: 22 Years and Up
Number of Pages: 244
Genre: Medical
Sub-Genre: Pharmacology
Publisher: American Medical Publishers
Format: Hardcover
Author: Erica Helmer
Language: English
Street Date: September 26, 2023
TCIN: 1004855673
UPC: 9798887403755
Item Number (DPCI): 247-03-2910
Origin: Made in the USA or Imported
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Shipping details
Estimated ship dimensions: 0.63 inches length x 8.5 inches width x 11 inches height
Estimated ship weight: 1.9 pounds
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