$11.96 when purchased online
Target Online store #3991
About this item
Highlights
- Soothing Lotion-Infused Tissue: Helps moisturize skin and reduce nose soreness.
- Mega Cube Format: Extra tissues per box mean fewer restocks needed.
- Gentle & Strong: 2-ply strength built to handle frequent use without irritation.
- Perfect for Cold & Allergy Season: Essential for relief during sniffles and sneezes.
- Double Pack Convenience: Two boxes to keep comfort handy in multiple rooms.
Description
Puffs Plus Lotion Facial Tissues, 2 Mega Cube Boxes, 72 Tissues Per Box, provide soothing relief for sore, irritated noses. Infused with a touch of lotion and enriched with aloe and vitamin E, these 2-ply tissues help protect your skin while offering strength and absorbency. Perfect during colds, flu, or allergy flare-ups, Puffs Plus Lotion is America’s #1 lotion tissue—trusted by families to be soft where it matters most.
Sheets Per Roll: 144
Product Warning: Keep out of reach of children
Disposability: Do not flush
Container Shape: Square
Package Quantity: 2
TCIN: 1003152700
UPC: 037000626169
Origin: made in the USA
The above item details were provided by the Target Plus™ Partner. Target does not represent or warrant that this information is accurate or complete. On occasion, manufacturers may modify their items and update their labels.
We recommend that you do not rely solely on the information presented. If you have a specific question about this item, you may consult the item's label, contact the manufacturer directly or call Target Guest Services at 1-800-591-3869.
If the item details above aren’t accurate or complete, we want to know about it.
Shipping details
Estimated ship dimensions: 9.21 inches length x 5.08 inches width x 4.84 inches height
Estimated ship weight: 0.76 pounds
item ships from third party seller: Hey Pharma
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
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4.2 out of 5 stars with 4407 reviews
Great product. Bring back the travel size.
5 out of 5 stars
ImzadiDragonfly - 14 days ago
originally posted on puffs.com
I love Puffs. I prefer the Puffs Plus Lotion. But I wish Puffs still made the travel size.
Best tissues!
5 out of 5 stars
carolynnd1_4503 - 15 days ago
originally posted on influenster.com

These are the only tissues we use in our house! They are so soft on your nose. I love that you can buy different sized boxes for this product depending on your needs
My savior!!!
5 out of 5 stars
1Monkey - 28 days ago
originally posted on puffs.com
I had a sneeze attack and went for the puff plus I just purchased. I could not get through the plastic! By they time I did and several sneezes later... PUFF PLUS held up to the job and save the day!
Great tissues
5 out of 5 stars
raelynacamero_7972 - 29 days ago
originally posted on influenster.com

These are definitely my go to for allergy season! No scent, great durability so they don’t rip easily and pretty great price for your money so I definitely recommend if you’re thinking about tissues!
Scratchy and so disappointing
1 out of 5 stars
Shelltheresnose - 1 month ago
originally posted on puffs.com
These have changed and are now scratchy and painful when you have a sore nose! I couldn’t believe it, I bought these because I had a cold and my nose was getting so sore. They felt like sandpaper on my poor, red nose. I’ll never buy them again. They are not how they used to be!
1 reply from Customer Care team - 1 month ago
We're sorry to hear this, and want to assure you that we test to ensure Puffs provide the comfort you need, and are safe to use as directed. If you haven't already, we recommend to stop using the product. We'd like to learn more about your experience to help, as well as share this with our Safety Team. When you have a chance, please get in touch with us at (800) 777-8337.
Soft yet durable
5 out of 5 stars
pamc78_2131 - 1 month ago
originally posted on influenster.com

Durable tissue but still soft on your nose and face. No irritation for sensitive skin. Absorbs great. No weird scent. Leaves your nose feeling clean and not raw like some brands. Could be a bit cheaper for the amount in the box but willing to pay the price for the quality.
Not what it used to be!
1 out of 5 stars
Redwest - 1 month ago
originally posted on puffs.com
We have been buying Puff's Plus Lotion 4 pack cubes for a lot of years. For the last few months every box is bad. They are thinner, they shed, they don't have the lotion like they used to and for some reason they tear every time you try to get one out of the box. We are very seriously just considering buying the cheaper ones. Puff's Plus Lotion is no longer worth the extra cost.
1 reply from Customer Care team - 1 month ago
We aim to impress you with the consistent thickness, strength, and softness, of Puffs Plus, and we assure you this is not the quality we expect. Our pals in Quality Assurance work overtime to try and deliver a perfect tissue every time, so we're very sorry for your disappointment. So that we can learn more about your product and do our best to make things right, please call us at 1-800-777-8337, M-F, 9 AM - 6 PM EST.
Love this product but inconsistent
4 out of 5 stars
Roberto444 - 2 months ago
originally posted on puffs.com
I love puffs plus lotion tissues. They do a great job keeping my nose from drying out. Unfortunately I think I may have gotten a bad batch this time around. Every ten or so tissues there is a tissue with no lotion! Very rough. I just throw the unmoisturized tissues away. I want to see you do better Puffs and I really mean that.
Full of lint
4 out of 5 stars
LizB - 2 months ago
originally posted on puffs.com
I've been buying these tissues for years. This is the first time I have run into this problem. I grabbed a tissue lint went all over me. It happened several times.
Used for years
5 out of 5 stars
Booger - 2 months ago
originally posted on puffs.com
I’ve been using these tissues for many years. I think this is the first time I found a booger on one!
The perfect softness
5 out of 5 stars
rachaeld04_1512 - 2 months ago
originally posted on influenster.com

Puffs Plus Lotion tissues are a total game-changer when you’re dealing with a cold or allergies. They’re super soft and have just the right amount of lotion to keep your nose from getting red and irritated, even after constant use. Unlike regular tissues that can feel rough, these are gentle and hold up really well without falling apart. They also have a nice, clean feel that makes you actually want to reach for one. Honestly, they’re a must-have around the house, especially during sniffle season!
What happened??
1 out of 5 stars
Christy27 - 3 months ago
originally posted on puffs.com
These used to be my go-to, despite the higher cost. I have allergies and my nose got raw with anything else. This latest batch has a whole different texture, nubby rather than smooth. And there’s no trace of lotion. They’re downright painful to use. I bought three boxes; what am I supposed to do?
1 reply from Customer Care team - 2 months ago
We're very sorry you had this experience, Christy. We check the quality of our products many times during the manufacturing process, because your safety and comfort are so important to us at Puffs. We're disappointed our Puffs didn't measure up, and we'd like to speak with you about it. If you could please reach out to us at your earliest convenience, we'd like to collect further details from you about your experience. You can reach us Monday through Friday, 9:00am - 6:00pm EST, at 1-800-777-8337. Thank you, and we look forward to hearing from you. -The Puffs Team
Where are the pocket-size Puffs?
5 out of 5 stars
JoBa - 3 months ago
originally posted on puffs.com
As a severe allergy sufferer, I love Puffs with lotion. However, I am disappointed that I can no longer get Puffs in the pocket-size packages. These packages are more discrete in professional/public situations than the boxes.
Production issues
3 out of 5 stars
Hope45416 - 3 months ago
originally posted on puffs.com
I dont know why, but lately every box we get has tissues that are torn and tissues that have a bunch of linty stuff that gets all over the place. Maybe consider better quality control people.
1 reply from Customer Care team - 3 months ago
We have strict quality controls in place to ensure our best reaches you, and we're sorry to hear that your latest boxes have been arriving in this condition. The softness of facial tissues is directly related to the amount of lint. The softer the paper, the more lint there may be. However, an excess of lint can build up on the manufacturing line. To fit this, we regularly shut down our manufacturing lines to remove excess lint that could drop onto products to make your you receive our best. We'd really like to see how we can help, and make this right. Please call us at 1-800-777-8337 Monday-Friday 9am-6pm EST.
Puffs Plus Lotion is Perfect!
5 out of 5 stars
elizabeths1067_4486 - 3 months ago
originally posted on influenster.com

Puffs Plus Lotion is my favorite tissue and the ONLY one that I will purchase. I normally opt for store brands to save money when possible, but I will spend top dollar for Puffs Plus Lotion every single time! When I am sick, blowing my nose constantly, Puffs never makes my nose red, dry, and sore like other brands. I keep Puffs close by when I am sick. Just getting over a bad cold now, and with Puffs, my nose is moisturized and comforted. There is no scent to the tissues and they come out one at a time. Thanks, Puffs!
You destroyed your product
1 out of 5 stars
Mstormy - 3 months ago
originally posted on puffs.com
I can't believe what you did to puffs there is no lotion you got cheap so don't advertise it with lotion cuz there is nothing these were my favorite tissues and you destroyed them
1 reply from Customer Care team - 3 months ago
Please know that we want you to enjoy using Puffs every time you sneeze, sniffle or blow your nose. We have many quality checks in place to make sure that your Puffs are soft and with the lotion you love when you need it, and we're sorry if your recent purchase doesn't measure up to your standards. We'll be sure to share your experience with our Quality Team and thank you for bringing this to our attention.
Gentle on all noses
5 out of 5 stars
corif6_5694 - 3 months ago
originally posted on influenster.com

Soft tissue that doesn’t leave nose red and irritated after constant wiping or blowing. The tissues come out one at a time and don’t clump up. Affordable price too!
Good but expensive
4 out of 5 stars
srishtij14_3450 - 3 months ago
originally posted on influenster.com

I find it a little expensive. However, I will think the tissues are pretty soft! It feels super soft on the skin. They are scentless. Packaging is friendly as well.
PLEASE bring back the To Go Packs!
5 out of 5 stars
SteveE - 4 months ago
originally posted on puffs.com
I have used Puffs Plus Lotion To Go Packs for many years. I bought them in the 96 bulk package. I am so disappointed to see that they have been discontinued. There is no product as good on the market today. Please bring them back!!!
1 out of 3 tested (6 total) boxes is SCENTED
1 out of 5 stars
Micky78 - 4 months ago
originally posted on puffs.com
I’ve used these tissues for years to avoid raw noses when sick. But a recent box had a strong fabric softener scent. I have allergy-induced asthma and am sensitive to smells, so this is bad for my health. It’s disappointing that this slipped through quality control.
1 reply from Customer Care team - 4 months ago
Thanks for your valuable feedback, which we'll share with our Quality Assurance and Safety Teams. Consumer safety is our number one priority when making our tissues, so we'd certainly recommend discontinuing any further use of the scented tissues you found. Please call us at (800) 777-8337, and we'll be happy to help make this up to you!