Steroid-free options focus on topical anesthetics, cooling agents, and skin protectants. Examples listed include pramoxine (1%), menthol (0.5%), combinations of pramoxine with menthol, and calamine-based skin-protectant formulations — all of which reduce itch by numbing the skin, producing a cooling sensation, or protecting and drying irritated areas.

Common over-the-counter package sizes shown include 1 ounce, 2 ounces, 4 ounces, 6 fl oz (US), and 7.5 fl oz (US). Not every product listing includes size information.

Formulations intended for oozing or weeping rashes typically include drying and skin-protectant ingredients. Examples noted are calamine lotion and products containing zinc acetate or other protectants that help dry the area and form a protective layer over the skin.

Many products specify use for adults and children aged 2 years and older; some expressly advise against use in children under 2 and recommend consulting a doctor. Common warnings include keeping products out of reach of children and cautions about eye irritation or consulting a healthcare provider if pregnant or nursing.

Where directions are provided, application is typically up to three to four times daily to affected areas. Several product descriptions do not specify frequency in the available details.

Common soothing or moisturizing ingredients listed include aloe, plant-derived squalane, jojoba oil, and in some formulas witch hazel extract. A few products also mention vitamins C and E among their moisturizing ingredients.

Some listings claim itch relief in as little as five minutes or within ten minutes. One listing notes relief can last up to about 10 hours when used as directed. Not every product specifies onset time or duration.