They are available as topical creams and gels, oral liquids and chewables, standard tablets, and caplets.
Labeling varies by product: some list use from 0–36 months, many children's acetaminophen products are labeled for 2 years and up (with dosing guidance for ages 2–11), and several oral or systemic options are labeled for 12 years and older.
Topical formulations advertise instant or rapid numbing. Some children's oral liquids report pain (and fever) reduction in as little as 15 minutes.
Duration varies by product: an NSAID option lists up to 12 hours per dose. Topical numbing gels often provide short‑term relief for many users (sometimes around an hour), though some users report longer-lasting effects in certain cases.
Children's acetaminophen liquids and chewables commonly advise repeating doses every 4 hours and warn not to exceed five doses in 24 hours. A topical toothache cream notes application to the affected area up to four times daily.
Listed strengths include 20% benzocaine for topical products; children's liquid acetaminophen at 160 mg per 5 mL (with some items showing 100 mg in certain details); 500 mg acetaminophen tablets; and 220 mg naproxen sodium caplets.
