Target New ArrivalsGift Ideas for DadClothing, Shoes & AccessoriesHome & DecorKitchen & DiningOutdoor Living & GardenGroceryHousehold EssentialsBabyBeautyPersonal CareSports & OutdoorsHealthWellnessLuggageSchool & Office SuppliesToysElectronicsVideo GamesMovies, Music & BooksParty SuppliesGift IdeasGift CardsPetsUlta Beauty at TargetShop by CommunityTarget OpticalDealsClearanceNew ArrivalsGift Ideas for DadBack to SchoolCollegeTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Neutrogena On-The-Spot Acne Treatment with Benzoyl Peroxide - 0.75oz: Facial Cream, Noncomedogenic, Oil-Free, For Normal to Oily Skin - 2 of 4Neutrogena On-The-Spot Acne Treatment with Benzoyl Peroxide - 0.75oz: Facial Cream, Noncomedogenic, Oil-Free, For Normal to Oily Skin - 3 of 4Neutrogena On-The-Spot Acne Treatment with Benzoyl Peroxide - 0.75oz: Facial Cream, Noncomedogenic, Oil-Free, For Normal to Oily Skin - 4 of 4
Neutrogena On-The-Spot Acne Treatment with Benzoyl Peroxide - 0.75oz: Facial Cream, Noncomedogenic, Oil-Free, For Normal to Oily Skin - 1 of 4

Neutrogena On-The-Spot Acne Treatment with Benzoyl Peroxide - 0.75oz: Facial Cream, Noncomedogenic, Oil-Free, For Normal to Oily Skin

In Stock

Eligible for registries and wish lists

Save 5% every day

With Target Circle™ Card

At a glance

About this item

Highlights

  • Neutrogena On-the-Spot Acne Spot Treatment with 2.5% benzoyl peroxide to target acne breakouts
  • Vanishing cream formula absorbs quickly and dries clear for invisible daily acne treatment
  • Acne-fighting cream goes deep into pores to prevent breakout-causing acne bacteria
  • Clear drying benzoyl peroxide spot treatment helps clear breakouts & helps prevent new acne pimples
  • Lightweight and oil-free formula won’t clog pores or overly dry out acne-prone skin
  • Gentle acne cream can be used up to 3x daily on oily, combination, or blemish-prone skin
  • Effective acne medication that helps treat and reduce pimples from forming
  • Fast-acting pimple treatment prevents blemishes without over drying

Description

Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% benzoyl peroxide is a clinically proven acne spot treatment for face that helps clear breakouts fast without over-drying, stinging, or burning. This gentle vanishing cream formula absorbs quickly, works invisibly, and is designed for acne-prone and dry skin. The lightweight cream penetrates deep into pores to kill acne bacteria that cause pimples and helps prevent new ones from forming. Suitable for daily use, this acne treatment for face can be applied up to three times a day to affected areas. The 0.75 oz tube is perfect for targeted application and on-the-go use. This acne spot treatment cream is formulated to address the needs of those with acne-prone and dry skin, providing a vanishing cream that ab-sorbs quickly and leaves no residue. Neutrogena On-The-Spot Acne Spot Treatment Cream is an essential addition to your personal care products, delivering targeted acne control and supporting your skin care goals.
Scent: Unscented
Health Facts: Dye-Free, Noncomedogenic, Contains Benzoyl Peroxide, Oil-Free, Phthalate-Free
Product Form: Cream
Beauty Purpose: Oil Control, Pore Cleansing, Spot Treatment, Pore Reduction, Skin Texture Improvement
Recommended Skin Type: Oily, Acne-Prone, Normal, Combination
Net weight: .75 Ounces
Features: Dermatologist Recommended
TCIN: 13337868
UPC: 070501017906
Item Number (DPCI): 037-12-0734
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

benzoyl peroxide(2.5%).

Purpose

Acne Medication..

Do not use if you

Do not use if you: have very sensitive skin,are sensitive to benzoyl peroxide.

When using this product

When using this product: avoid unnecessary sun exposure and use sunscreen,avoid contact with the eyes, lips, and mouth,avoid contact with hair and dyed fabrics, which may be bleached by this product,skin irritation may occur, characterized by redness, burinng, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.

Stop use and ask a doctor if

Stop use and ask a doctor if: irritation becoems severe.

Directions

Clean the skin thoroughly before applying this product. Cover the entire affected area with a thin layer one to three times daily. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. If going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.

Other information

Store at 20 degrees C-25 degrees C (68 degrees F-77 degrees F).

Inactive ingredients

water, carbomer homopolymer type b, ethylhexylglycerin, sodium hydroxide, chlorphenesin, disodium edta, laureth-4, hydroxypropyl methylcellulose

Question or comments?

800-582-4048

Ingredients:

active ingredient: water, carbomer homopolymer type b, ethylhexylglycerin, sodium hydroxide, chlorphenesin, disodium edta, laureth-4, hydroxypropyl methylcellulose

Shipping details

Estimated ship dimensions: 1.37 inches length x 3.85 inches width x 4.09 inches height
Estimated ship weight: 0.08 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.
Download the safety data sheet (PDF)
This document lists product hazards, safety info and any potential ill effects on human health. All info has been collected and verified by the manufacturer.

Q: Is this a clear or is it skin tone color cream

submitted by norcali - 2 years ago

  • A: it's white, but goes on and dries clear

    submitted byStella - 9 months ago

  • A: This product goes on clear, and is clinically proven to be so effective that skin starts getting clearer on day 1.

    submitted byKenvue - 2 years ago
    Brand expert

Q: Can you use this product even when your going to be exposed to UV rays? The products I get from my dermatologist I cannot

submitted by Lindsey - 6 years ago

  • A: Hi Lindsey! We recommend using sunscreen when going outdoors while using the Neutrogena On-The-Spot Acne Treatment. We recommend Neutrogena's Oil Free Facial Moisturizer with SPF 35. Hope this helps!

    submitted byTarget Beauty Consulting - 6 years ago
    Brand expert

  • A: Hi Lindsey! If you plan on going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.

    submitted byKenvue - 5 years ago
    Brand expert

Q: Is the cream designed for invisible application?

submitted by AI Shopping Assistant - 3 months ago

  • A: Yes, the vanishing cream formula absorbs quickly and dries clear for invisible daily use.

    submitted byAI Shopping Assistant - 3 months ago
    Ai generated

Q: What is the active ingredient in this acne treatment?

submitted by AI Shopping Assistant - 3 months ago

  • A: The active ingredient in this treatment is 2.5% benzoyl peroxide, which targets acne breakouts.

    submitted byAI Shopping Assistant - 3 months ago
    Ai generated

Q: What skin types is this product suitable for?

submitted by AI Shopping Assistant - 3 months ago

  • A: This product is suitable for oily, acne-prone, normal, and combination skin types.

    submitted byAI Shopping Assistant - 3 months ago
    Ai generated

Q: Can this treatment be used on dry skin?

submitted by AI Shopping Assistant - 3 months ago

  • A: Yes, it is formulated to suit acne-prone and dry skin types without causing irritation.

    submitted byAI Shopping Assistant - 3 months ago
    Ai generated

Q: How often can I apply this acne treatment?

submitted by AI Shopping Assistant - 3 months ago

  • A: You can apply this treatment up to three times daily on affected areas.

    submitted byAI Shopping Assistant - 3 months ago
    Ai generated

Q: Does this help reduce redness and scarring from pimples after they are popped?

submitted by Laurielox - 4 months ago

  • A: Hi, we have not tested the product to see if it will reduce redness and scarring.

    submitted byKenvue - 4 months ago
    Brand expert

Q: What other same brand products could you recommend if your wanting to continue using this brand for your skin care routine? And does this fight under eye black circles? And hollowing eyes?

submitted by Ebbie - 6 months ago

  • A: Hi! The Neutrogena On-The-Spot Treatment for Acne Prone Skin Care it’s not specifically targeted for under-eye concerns like hollowing, bags, or really all types of dark under-eye circles. If you’re already using Neutrogena and want to continue with their skincare line especially to address under-eye dark circles, we recommend the Neutrogena Collagen Bank Reviving Eye Cream.

    submitted byKenvue - 6 months ago
    Brand expert

Q: Is this Pregnancy Safe?

submitted by Anonymous - 1 year ago

  • A: Hello there! Thanks for choosing our product! While our Neutrogena Neutrogena On-The-Spot Acne Spot Treatment for Acne Prone Skin Care is generally considered safe, it's always best to consult with your obstetrician or dermatologist before introducing any new skincare products during pregnancy to ensure they align with your individual health needs.

    submitted byKenvue - 1 year ago
    Brand expert
See all questions (16)

Additional product information and recommendations

Discover more options

Frequently bought together

Guests also viewed

4.1 out of 5 stars with 1459 reviews
effectiveness: 3.53 out of 5
quality: 3.45 out of 5
value: 3.51 out of 5
60% would recommend
82 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
21 May, 2026Verified purchase

(no review title)

Does the Trick for on the Stop flair ups 👍🏿like
Nakise
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
27 April, 2026Verified purchase

Cheap Remedy that Works!

I had red pimples showing up on my neck. Within a week of use, they were all cleared up.
Eric
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
3 out of 5 stars
Thumbs down graphic, would not recommend
22 March, 2026

not good

does not work very well also gives the same irritation as a stronger benzoyl peroxide.
Kevin
effectiveness: 2 out of 5
quality: 4 out of 5
value: 2 out of 5
Did you find this review helpful?
2 out of 5 stars
19 February, 2026
originally posted on influenster.com
Image

Ok

Not the best spot acne treatment in my experience. For more cystic or acne prone skin type it won’t help. For those not prone to acne might help but does take a couple uses to see improvements .
KatrienaC
Did you find this review helpful?
5 out of 5 stars
18 February, 2026
originally posted on influenster.com
Image

Very good

Light scent, great coverage, noticeable results and excellent lasting power, it really performs well and keeps my skin looking clearer all day, I like this product
LeciaC
Did you find this review helpful?
4 out of 5 stars
13 February, 2026
originally posted on influenster.com
Image

This Is GOLDEN

Omg!!! This is GOLDEN! Honestly a great buy for quick acne clear up. I generally don’t have much but definitely made me look as good as new🥹🤏🏾 doesn’t have too much of a strong scent and it feels super light on the skin too!
somickii_9699
1 guest found this review helpful. Did you?
5 out of 5 stars
11 February, 2026
originally posted on influenster.com
Image

Try it now!!

If you are a person who has consistent breakouts this product is for you!! It has easy application, great size for the price and is VERY effective. It cleared up my very acne prone skin within 2-3 days
lilynicoles_756
Did you find this review helpful?
5 out of 5 stars
11 February, 2026
originally posted on influenster.com
Image

Fast and drying. Quick outcome

This acne treatment works as a fast drying solution for that issue you are having. I would say it works on all skin types and is versatile for everyone use
BrianaP
Did you find this review helpful?
4 out of 5 stars
10 February, 2026
originally posted on influenster.com
Image

Helped with acne

I used to use this a long time ago when I had really bad acne, and this was one of the products that helped me get rid of it long-term. I have dry skin, but this did not dry out my skin further.
shreyap70_9093
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
6 February, 2026Verified purchase

AMAZING

I was having random breakouts and I wasn’t sure why so I got this…. It worked SO WELL in less than 24 hours. just after the first application I saw a HUGE difference! This may be a small bottle with a higher price than it should but I will for sure keep buying this!!
Emily
effectiveness: 5 out of 5
quality: 5 out of 5
value: 4 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
5 February, 2026
originally posted on influenster.com
Image

Highly recommend

I have tried so many acne spots treatments, and this one by far is the best. I use it on my blemishes, and it reduces the redness and swelling overnight. It leaves no white residue. I dont have peeling or dryness. Use a moisturizer afterward. Just use a tiny dab. It goes a long way.
StormiB
Did you find this review helpful?
5 out of 5 stars
4 February, 2026
originally posted on influenster.com
Image

Get it

This acne cream is my top go too! The value for the buck on this amazing product is just amazing. It absorbs great and scent is perfect for the fine skin leaving no residue behind.
Anna B
Did you find this review helpful?
4 out of 5 stars
3 February, 2026
originally posted on influenster.com
Image

Works well - non drying

This acne spot treatment works quickly and without drying out your skin. I don’t notice any pilling even when I use it under makeup. It goes on smoothly and does not irritate your skin.
jessicaa36_8246
Did you find this review helpful?
2 out of 5 stars
1 February, 2026
originally posted on influenster.com
Image

Eh

Dried on my skin to where it pilled, my skin was blotchy, just did not work for my cystic acne. The consistency is like a gel. I would only leave on skin for five minutes before having to remove.
meganc724_4576
Did you find this review helpful?
5 out of 5 stars
30 January, 2026
originally posted on influenster.com
Image

Great

This acne spot treatment is so good!! Just apply a small amount and it helps draw everything right out!! I put this on right before bed. It works great
cjsxcountrygirl_7506
Did you find this review helpful?
4 out of 5 stars
28 January, 2026
originally posted on influenster.com
Image

My go to

I have been using this product for a little over a year now, and I stand behind it with everything I have. My skin is super oily and sensitive and dries out very easily. I put this on before I go to bed on any trouble spots and wake up with them 75 to 100% gone. Now I’m sure it would work better if I didn’t touch my face all the time, but it is at least helping.
CrissyD
Did you find this review helpful?
5 out of 5 stars
26 January, 2026
originally posted on influenster.com
Image

Helps spot treat!

I’ve been using this for over a year, this is my third bottle. I have acne prone skin and I spot treat with this. This will dry out acne overnight! I also apply it on top of acne throughout the day to keep it drying and honestly, works way better than pimple patches for me. Doesn’t cause any irritation.
christinal590_1455
Did you find this review helpful?
5 out of 5 stars
24 January, 2026
originally posted on influenster.com
Image

It works quickly

One of the only products I’ve used that works! Used this for years with plenty of success. It works quickly and gets rid of annoying spots that refuse to go away.
ashleighb200_4394
Did you find this review helpful?
5 out of 5 stars
9 January, 2026
originally posted on influenster.com
Image

Works wonders on acne

I love this product! It goes a really long way. You just put a tiny bit of the cream on the acne and it does wonders. The before after photos are just 2 days apart. Works the best on active acne or acne on its early days. It does irritate your skin a bit as it dries the acne so don’t put on too much.
irmakt1_1922
1 guest found this review helpful. Did you?
4 out of 5 stars
8 January, 2026
originally posted on influenster.com
Image

Effective but drying

I find benzoyl peroxide to be a great product for treating acne spots. This product is very drying, so it should be paired with a good moisturizer on top.
maevec30_3097
Did you find this review helpful?

Get top deals, latest trends, and more.

Privacy policy