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Differin 10% Benzoyl Peroxide Acne Spot Treatment
$7.86 reg $10.49
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About this item
Highlights
- MAXIMUM STRENGTH 10% BENZOYL PEROXIDE: One 1 oz tube of Differin Acne Spot Treatment with 10% benzoyl peroxide as the strongest over-the-counter (OTC) concentration to visibly reduce acne size and redness after 1 use.
- FAST BLEMISH SPOT TREATMENT: Penetrates deep into pores and works to immediately kill acne-causing bacteria
- FOUR-IN-ONE ACNE TREATMENT FOR FACE: Acne solution that treats imperfections, prevents acne, targets acne-causing bacteria, and improves skin texture
- FORMULATED WITH GLYCERIN: While benzoyl peroxide starts clearing acne blemishes, glycerin helps to minimize dryness
- ACNE SPOT TREATMENT: Acne treatment for face and body use, developed for acne-prone skin
Description
Differin 10% Benzoyl Peroxide Spot Treatment is an acne treatment for face and body use, developed for acne-prone skin. This four-in-one solution treats acne, prevents acne, kills acne-causing bacteria, and improves skin texture. Formulated with 10% benzoyl peroxide, the strongest OTC concentration without a prescription, and glycerin to minimize dryness, it immediately targets acne-causing bacteria and effectively prevents imperfections. This multi-action pimple cream clears and treats acne, whiteheads, blackheads, and clogged pores, visibly reducing size and redness after first use. Use as part of your skincare routine to treat and clear acne and other imperfections. After cleaning with a facial cleanser, apply on dry skin directly on affected areas. Follow up with a moisturizer and SPF in the morning and night cream at night. Reapply as needed. Dry skin may occur while using this product, so start with one application daily and gradually increase it if needed.Key Ingredient:Benzoyl Peroxide
Scent: Unscented
Health Facts: Hypoallergenic
Product Form: Gel
Disposability: Do not flush
Primary Active Ingredient: Benzoyl Peroxide
Package Quantity: 1
Beauty Purpose: Anti-Acne
Recommended Skin Type: Acne-Prone
Net weight: 1 fl oz (US)
Features: Non-Comedogenic, Safe to Use On Sensitive Skin, Dermatologist Tested, Lightweight, Dermatologist Recommended
TCIN: 91370206
UPC: 302994611003
Item Number (DPCI): 037-12-4525
Origin: Assem USA w/foreign/dom. parts
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.
Active ingredients
benzoyl peroxide' '10.0%
Purpose
Acne treatmentUses
Use For the treatment of acneDirections
Directions Sensitivity Test for a New User. Apply product sparingly to one or two small affected areas during the first 3 days. If no discomfort occurs, follow the directions stated below, clean the skin thoroughly before applying this product, cover the entire affected area with a thin layer one to three times daily, because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor, if bothersome dryness or peeling occurs, reduce application to once a day or every other day, if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctorInactive ingredients
inactive ingredients acrylates copolymer, carbomer, diethylhexyl sodium sulfosuccinate, disodium edta, glycerin, poloxamer 182, propylene glycol, silica, sodium hydroxide, water' '
Shipping details
Estimated ship dimensions: 1.84 inches length x 2.71 inches width x 6.48 inches height
Estimated ship weight: 0.12 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
Q: Do I have to wash this off after a certain of using it?
submitted by Angel - 19 days ago
A: Hey Angel, Great question! We recommend to wash your face 2x a day and apply the Differin 10% Benzoyl Peroxide Acne Spot Treatment on dry skin, directly on the affected areas. For real-time answers to all your beauty questions, use the “Chat with a Virtual Beauty Consultant” button on any beauty product page. https://www.target.com/c/beauty/-/N-55r1x
submitted byTarget Beauty Consulting - 18 days agoBrand expert
Q: How should the treatment be applied?
submitted by AI Shopping Assistant - 2 months ago
A: Apply on dry skin directly on affected areas after cleansing. Follow with moisturizer and SPF in the morning, night cream at night.
submitted byAI Shopping Assistant - 2 months agoAi generated
Q: What is the primary active ingredient in this treatment?
submitted by AI Shopping Assistant - 2 months ago
A: The primary active ingredient is benzoyl peroxide at a 10% concentration.
submitted byAI Shopping Assistant - 2 months agoAi generated
Q: Does this treatment help with blackheads?
submitted by AI Shopping Assistant - 2 months ago
A: Yes, it clears and treats acne, whiteheads, blackheads, and clogged pores.
submitted byAI Shopping Assistant - 2 months agoAi generated
Q: Can this product be used on the body?
submitted by AI Shopping Assistant - 2 months ago
A: Yes, it is developed for both face and body use.
submitted byAI Shopping Assistant - 2 months agoAi generated
Q: What skin types is this product recommended for?
submitted by AI Shopping Assistant - 2 months ago
A: This product is recommended for acne-prone skin and is safe for sensitive skin.
submitted byAI Shopping Assistant - 2 months agoAi generated
Q: Can I use on entire face? I have a lot of pop up pretty much all over and don’t want to get it if it only is for small areas.
submitted by Its alright - 5 months ago
A: Great question! It should be applied directly to individual blemishes rather than all over the face. While some people may use it on a wider area, it's generally not recommended for full-face application due to the potential for excessive dryness and irritation. For real-time answers to all your beauty questions, use the “Chat with a Virtual Beauty Consultant” button on any beauty product page.
submitted byTarget Beauty Consulting - 5 months agoBrand expert
Q: is this spot treatment safe to use while nursing?
submitted by saddeypassey - 1 year ago
A: Hey, Women who are pregnant or breastfeeding should check with their physician before using any new skincare products. For all your future beauty questions, get real-time answers using the “Chat with a Virtual Beauty Consultant” button, found on every product page.
submitted byTarget Beauty Consulting - 1 year agoBrand expert
Q: Will this help the most for people who have HS?
submitted by Betty wu - 1 year ago
A: Hi @username! Our Maximum Strength Acne Foaming Cleanser with 10% Benzoyl Peroxide cleanses the skin with a dual action formula that starts working immediately to help eliminate 99.99% of acne causing bacteria in 15 seconds! Benzoyl peroxide is an acne-fighting ingredient that prevents the buildup of bacteria that causes acne deep in the pores. It’s recommended more often by derms than salicylic acid and sulfur. However, we recommend reaching out to your dermatologist to find products that work for your specific skin type and needs. We hope this helps!
submitted byGalderma Team Member - 1 year agoBrand expert
Differin Acne Complete Collection
About the collection
Treat current breakouts and prevent future acne with a regimen of Differin cleansers, moisturizers, treatments and patches. Explore the Differin portfolio with solutions ranging from powerful Rx strength ingredients to target acne all the way to ingredients designed to soothe, nourish and restore acne-prone skin. Differin offers a variety of products for face and body that are science backed, dermatologist recommended, and clinically tested to support every stop on your acne journey.
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Guests are saying
The Differin 10 BPO Spot Treatment is a highly effective solution for acne, praised for its quick results and gentle formula. Guests appreciate its lightweight texture, minimal scent, and practical packaging, making it easy to incorporate into any skincare routine. While some users noted that it can be drying, many found it to be a game changer in managing breakouts, with noticeable improvements often seen within days of use. This product is ideal for those seeking a reliable spot treatment for stubborn acne.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.5 out of 5 stars with 322 reviews
effectiveness: 3.67 out of 5
quality: 3.91 out of 5
value: 4.18 out of 5
64% would recommend
14 recommendations
5 out of 5 stars
24 November, 2025
originally posted on influenster.com
Reduced spots so quick!
[This review was collected as part of a promotion.] Okay so I was super skeptical about this at first because I’ve tried literally everything for my random pimples and nothing really works. But wow, this stuff is actually magic. I put it on a stubborn spot at night and literally by the next morning it was way smaller and way less red. The texture is a little thick but it doesn’t feel gross or sticky, and it dries down nicely so I can put my moisturizer over it without any weird feeling. I’ve been using it for a couple of weeks now and my breakout spots don’t last nearly as long, which is honestly life changing. This is officially my go to “emergency zit zapper” and I tell anyone with annoying pimples to give it a try because it actually works.
5 out of 5 stars
Thumbs up graphic, would recommend
4 November, 2025Verified purchase
Works Great!!
Holy Cow this stuff works! I have been having a hard time getting rid of acne and nothing was seem to get rid of it. I did some research and found this stuff and thought I would give it a try! Day one I noticed a difference, day I went to put more on before bed and could barely see my acne. I am very pleased and will be using/buying again!! It does leave some white residue like past reviews say, but comes off very easily with a baby wipe. Only thing I didn't like, was that in came in a big box for a small tube, waste of space and packaging, but my only complaint
5 out of 5 stars
28 October, 2025
originally posted on differin.com
Finally an Acne Product that is AMAZING!!
People Differen is the ULTIMATE Acne treatment a reasonably cheap product that works EFFICIENTLY and QUICKLY!! I had an Acne problem a blind pimple near my temple that wouldn't go away! From Day 2 of Differen it got rid of swelling pain redness!! Try this product! 5 Stars!!
4 out of 5 stars
25 October, 2025
originally posted on influenster.com
Great!!
[This review was collected as part of a promotion.] This was actually such a good product, unfortunately I downloaded the app again just recently so I don’t have the product anymore to take a picture of. Overall I loved it, packaging was good and it worked super well!
4 out of 5 stars
20 October, 2025Verified purchase
(no review title)
This spot treatment worked so good for my skin. I have been breaking out and this has been a life saver. Didn’t have any reactions or issues but for first time use definitely go slow
5 out of 5 stars
Thumbs up graphic, would recommend
14 October, 2025Verified purchase
rid of allergic rash on my face
this cream got rid of my allergic reaction rash on my face! I wish it had a thinner consistency so I felt better about layering hydrating serums on top, but it’s not a dealbreaker. def repurchasing for a lifetime
5 out of 5 stars
12 October, 2025
originally posted on influenster.com
Great for acne
[This review was collected as part of a promotion.] This was very effective in improving my acne. It was safe for my sensitive skin. No scent. It seems to be a good value for the money. Minimalistic packaging.
5 out of 5 stars
Thumbs up graphic, would recommend
8 September, 2025Verified purchase
Amazing!!
This has helped with my acne espeically for random flare ups. I apply it at night and in the morning it is diminished.
3 out of 5 stars
5 August, 2025
originally posted on influenster.com
Not worth it
[This review was collected as part of a promotion.] I have stubborn acne and was excited to try this product. It did not help that much. It mostly just dried out my skin and left hard to get rid of acne spots.
3 out of 5 stars
15 June, 2025
originally posted on influenster.com
Indifferent
[This review was collected as part of a promotion.] The product added dryness to the area it was applied on reducing the redness and bump of zits on my face but it did not completely remove a breakout. I think I’d stick with elf zit patches over this.
5 out of 5 stars
28 May, 2025
originally posted on influenster.com
It works!
[This review was collected as part of a promotion.] Did a great job with smaller blemishes, didn’t irritate my skin, and a little bit goes a long way! Simple easy to read instructions on packaging. And you get a good amount of product for the price. Didn’t notice too much of a smell, and it didn’t bother my sensitive nose.
5 out of 5 stars
Thumbs up graphic, would recommend
17 April, 2025Verified purchase
Works great!
I love this, it works like magic to remove blemishes. It is drying and my skin does react to it sometimes, so just a fair warning if you have sensitive skin like me that this product is strong.
1 out of 5 stars
Thumbs down graphic, would not recommend
13 March, 2025Verified purchase
did not work, gave me a rash
I have sensitive skin and this said it would be fine on sensitive skin. it made me break out in a rash and i also did not notice any difference. Maybe i am allergic to one of the ingredients, im not sure. Will be returning
1 out of 5 stars
Thumbs down graphic, would not recommend
27 February, 2025Verified purchase
Did not work
Didn't notice anything different while using this at all. Actual waste of my money.
5 out of 5 stars
19 February, 2025
originally posted on influenster.com
Pimples Be Gone!!!
[This review was collected as part of a promotion.] This cream did help resolve some of my acne from the face. It doesn’t really feel like you have put anything on because the substance is just so lightweight, which I really liked!!! The packaging was really cute to as shown in the picture above. If I were to buy it, I would purchase this item!!
5 out of 5 stars
30 January, 2025
originally posted on influenster.com
Works but pump is tricky
[This review was collected as part of a promotion.] However the pump is tricky. Invariably if you try to just pump a fresh bottle, one side won’t come out. You need to cover the holes with a finger and then give several small pumps. This will prime the pump and always resolves the issue for me, although on occasion I’ve had to repeat the process. Then before each use, tap the top of the bottle (with cap on!) against your palm a few times. I really wish they would somehow just fix this, as everyone seems to have the same issue and it’s been going on for years. But the product is well worth the cost and hassle of getting the pump going. Note, if you have sensitive skin like mine, you may not be able to use it every night. I use it every other night and my skin is able to tolerate it pretty well.
5 out of 5 stars
30 January, 2025
originally posted on influenster.com
Even better
[This review was collected as part of a promotion.] Best Benzoyl peroxide treatment ! It’s my first time trying a leave on treatment of bp. I’ve used the cleanser before. And I can say this is even more effective than the cleanser (which I already like)
5 out of 5 stars
30 January, 2025
originally posted on influenster.com
Nice Spot Treatment
[This review was collected as part of a promotion.] This is really an effective cream, I had an event to attend but I had the most stubborn product that was truly annoying but this came.in handy. I could see results as fast as 2-3 depending on how severe it was. The texture is simple and he has no particular scent it gets the job done
4 out of 5 stars
30 January, 2025
originally posted on influenster.com
Great product!
[This review was collected as part of a promotion.] I was recently sent the Differin 10% BPO Spot Treatment by Influenster and I really liked this product! It was very effective and I noticed my skin was a lot smoother and radiant. Nice texture with no scent. Overall I would definitely recommend.
5 out of 5 stars
30 January, 2025
originally posted on influenster.com
Works great!
[This review was collected as part of a promotion.] This spot treatment is effective and very easy to use! Benzoyl Peroxide helps to kill acne-causing bacteria and also has anti-inflammatory properties. It helps to reduce the size of pimples overnight and also minimizes redness. I recommend applying a small amount in a thin layer in order to avoid irritation or over drying. The packaging is small but you only need a pea-sized amount. The scent: it has a minimal scent, which is not overpowering. Highly recommend!