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Naproxen Tablets - 80ct - up&up™ - 2 of 4Naproxen Tablets - 80ct - up&up™ - 3 of 4Naproxen Tablets - 80ct - up&up™ - 4 of 4
Naproxen Tablets - 80ct - up&up™ - 1 of 4

Naproxen Tablets - 80ct - up&up™

$7.89 ($0.10/count) reg $9.29
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At a glance

About this item

Highlights

  • Packaging may vary. Same trusted quality
  • ACTIVE INGREDIENTS: This product contains naproxen sodium 220 mg, a pain reliever NSAID (nonsteroidal anti-inflammatory drug), and diphenhydramine hydrochloride 25 mg, a nighttime sleep-aid. Compare to the active ingredients of Aleve pm.
  • NIGHTTIME PAIN RELIEF: All Night Pain Relief PM provides up to 12 hours of pain relief.
  • FALL ASLEEP: All Night Pain Relief helps to relieve occasional sleeplessness associated with minor aches and pains. Helps you to fall asleep and stay asleep.
  • FALL ASLEEP: All Night Pain Relief helps to relieve occasional sleeplessness associated with minor aches and pains. Helps you to fall asleep and stay asleep.
  • GLUTEN FREE: This product is free of gluten.

Description

Compare to the active ingredients of Aleve pm. The aches and pains of the day can follow you into nighttime and prevent a good night’s rest. Get the rest you need tonight for a better tomorrow with a sleep aid and long-lasting pain relief medication. All Night Pain Relief PM caplets (capsule-shaped tablets) are a sleep aid plus 12-hour pain reliever that help with occasional sleeplessness associated with minor aches and pains. Take this nighttime sleep aid and pain reliever when you need help falling asleep and staying asleep. The active ingredients are naproxen sodium 220 mg, a pain reliever, and diphenhydramine hydrochloride 25 mg, a nighttime sleep-aid. This product does not contain gluten.


We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Suggested Age: 12 Years and Up
Active Ingredient Strength Value: 25 Milligrams
Product Warning: Keep out of reach of children, consult a doctor if you have stomach problems, do not use if you have ulcers, consult a doctor if you have glaucoma, consult a doctor if you are pregnant or nursing, consult a doctor if you have kidney disease
Product Form: Tablet
Primary Active Ingredient: Diphenhydramine
Package Quantity: 80
TCIN: 84689885
UPC: 370030014989
Item Number (DPCI): 094-01-2484
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

diphenhydramine hydrochloride' '25.0mg naproxen sodium (naproxen 200 mg) (nsaid)* *nonsteroidal anti-inflammatory drug' '220.0mg

Purpose

Nighttime sleep-aid Pain reliever

Uses

Uses for relief of occasional sleeplessness when associated with minor aches and pains, helps you fall asleep and stay asleep

Directions

Directions do not take more than directed, drink a full glass of water with each dose, adults and children 12 years and over: take 2 caplets at bedtime, do not take more than 2 caplets in 24 hours, if taken with food, this product may take longer to work

Other information

Other information read all warnings and directions before use. Keep outer carton. 1each caplet contains: sodium 21 mg, store at 20-25℃ (68-77℉), avoid high humidity and excessive heat above 40℃ (104℉)

Inactive ingredients

croscarmellose sodium, fd&c blue #1 aluminum lake, fd&c blue #2 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, silicon dioxide, talc, titanium dioxide

Shipping details

Estimated ship dimensions: 2.13 inches length x 2.32 inches width x 4.39 inches height
Estimated ship weight: 0.15 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: What is the active ingredient in these tablets?

submitted by AI Shopping Assistant - 2 months ago

  • A: The active ingredients are naproxen sodium 220 mg and diphenhydramine hydrochloride 25 mg.

    submitted byAI Shopping Assistant - 2 months ago
    Ai generated

Q: Can this product help with falling asleep?

submitted by AI Shopping Assistant - 2 months ago

  • A: Yes, it aids in falling asleep and staying asleep by relieving discomfort.

    submitted byAI Shopping Assistant - 2 months ago
    Ai generated

Q: How long does the pain relief last?

submitted by AI Shopping Assistant - 2 months ago

  • A: The All Night Pain Relief PM provides up to 12 hours of pain relief.

    submitted byAI Shopping Assistant - 2 months ago
    Ai generated

Q: Is this product suitable for those with gluten intolerance?

submitted by AI Shopping Assistant - 2 months ago

  • A: Yes, this product is gluten-free and suitable for those with gluten intolerance.

    submitted byAI Shopping Assistant - 2 months ago
    Ai generated

Q: What type of pain does this product help relieve?

submitted by AI Shopping Assistant - 2 months ago

  • A: It helps relieve minor aches and pains associated with occasional sleeplessness.

    submitted byAI Shopping Assistant - 2 months ago
    Ai generated
See all questions (5)

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Beware Of Non disclosure

Target changed the manufacfurer of these naproxen tablets without disclosing to the consumer.! (See the numbers on the pills) It is the same dosage and should still be effective as it is only a change in manufacturer. It is concerning because a consumer could be allergic or unable to take certain pills for whatever reason. Some manufacturers are not safe or effective for some people. Disclosure is vital when selling medication of any kind. Target if your going to be a medication brand Do Better in consumer safety ir dint do it at all!
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5 March, 2026Verified purchase

Some were expired

Ordered 7 boxes just to get free shipping. However, 2 of the 7 boxes were expired🥺
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Up & Up Naproxen PM Tablets

Excellent. Good pain relief & sleep aid. The Up & Up brand of Naproxen PM works just as good as the big name brands and at a much lower price.
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Great value

Great value! Same as named brands for a lot less!
stephspov
quality: 5 out of 5
value: 5 out of 5
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5 out of 5 stars
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Sleepytime and pain relief in one!

Great value, great product. Works as advertised and at a fraction of the cost of name brand. Helped relieve my body aches and get me to sleep!
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