Cytogenetic Laboratory Management - by Susan Mahler Zneimer (Paperback)

About the Book

"This title will provide cytogenetic, FISH and microarray laboratory standard operating procedures (SOP's) and information on how to effectively write SOP's; validation plans and summaries; chemical, safety, quality control and quality assurance programs; and plans for effective use of reagents, instruments and equipment"--

Book Synopsis

Cytogenetic Laboratory Management

Cytogenetic Laboratory Management

Chromosomal, FISH and Microarray-Based Best Practices and Procedures

Cytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures is a practical guide that describes how to develop and implement best practice processes and procedures in the genetic laboratory setting. The text first describes good laboratory practices, including quality management, design control of tests, and FDA guidelines for laboratory-developed tests, and preclinical validation study designs. The second focus of the book is on best practices for staffing and training, including cost of testing, staffing requirements, process improvement using Six Sigma techniques, training and competency guidelines, and complete training programs for cytogenetic and molecular genetic technologists. The third part of the text provides stepwise standard operating procedures for chromosomal, FISH and microarray-based tests, including preanalytic, analytic, and postanalytic steps in testing, which are divided into categories by specimen type and test type.

All three sections of the book include example worksheets, procedures, and other illustrative examples that can be downloaded from the Wiley website to be used directly without having to develop prototypes in your laboratory.

Providing a wealth of information on both laboratory management and molecular and cytogenetic testing, Cytogenetic Laboratory Management will be an essential tool for laboratorians worldwide in the field of laboratory testing and genetic testing in particular.

This book gives the essentials of:

• Developing and implementing good quality management programs in laboratories
• Understanding design control of tests and preclinical validation studies and reports
• FDA guidelines for laboratory-developed tests
• Use of reagents, instruments, and equipment
• Cost of testing assessment and process improvement using Six Sigma methodology
• Staffing training and competency objectives
• Complete training programs for molecular and cytogenetic technologists
• Standard operating procedures for all components of chromosomal analysis, FISH, and microarray testing of different specimen types

This volume is a companion to Cytogenetic Abnormalities: Chromosomal, FISH and Microarray-Based Clinical Reporting. The combined volumes give an expansive approach to performing, reporting, and interpreting cytogenetic laboratory testing and the necessary management practices, staff and testing requirements.

From the Back Cover

Cytogenetic Laboratory Management

Chromosomal, FISH and Microarray-Based Best Practices and Procedures

Cytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures is a practical guide that describes how to develop and implement best practice processes and procedures in the genetic laboratory setting. The text first describes good laboratory practices, including quality management, design control of tests, and FDA guidelines for laboratory-developed tests, and preclinical validation study designs. The second focus of the book is on best practices for staffing and training, including cost of testing, staffing requirements, process improvement using Six Sigma techniques, training and competency guidelines, and complete training programs for cytogenetic and molecular genetic technologists. The third part of the text provides stepwise standard operating procedures for chromosomal, FISH and microarray-based tests, including preanalytic, analytic, and postanalytic steps in testing, which are divided into categories by specimen type and test type.

All three sections of the book include example worksheets, procedures, and other illustrative examples that can be downloaded from the Wiley website to be used directly without having to develop prototypes in your laboratory.

Providing a wealth of information on both laboratory management and molecular and cytogenetic testing, Cytogenetic Laboratory Management will be an essential tool for laboratorians worldwide in the field of laboratory testing and genetic testing in particular.

This book gives the essentials of:

• Developing and implementing good quality management programs in laboratories
• Understanding design control of tests and preclinical validation studies and reports
• FDA guidelines for laboratory-developed tests
• Use of reagents, instruments, and equipment
• Cost of testing assessment and process improvement using Six Sigma methodology
• Staffing training and competency objectives
• Complete training programs for molecular and cytogenetic technologists
• Standard operating procedures for all components of chromosomal analysis, FISH, and microarray testing of different specimen types

This volume is a companion to Cytogenetic Abnormalities: Chromosomal, FISH and Microarray-Based Clinical Reporting. The combined volumes give an expansive approach to performing, reporting, and interpreting cytogenetic laboratory testing and the necessary management practices, staff and testing requirements.

Review Quotes

"From beginning to end, this book provides relevant concepts, procedures and strategies that give the reader a complete overview of good laboratory practices. In addition to providing an excellent guide for setting up a new clinical lab, Zneimer's book should be considered as a useful guide for any laboratory because it provides a wealth of practical information that can be used on a daily basis. All of the spreadsheets, guides, examples and templates in the book are useful bonus features and represent a valuable legacy of the author's extensive experience." (Phenotype June 2017)

About the Author

SUSAN MAHLER ZNEIMER, Ph.D., FACMGG, is a clinical cytogeneticist, is the scientific director and CEO of MOSYS Consulting, and an adjunct professor at Moorpark College in Moorpark, California, USA.