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Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency

Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency - 2 of 4Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency - 3 of 4Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency - 4 of 4
Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency - 1 of 4
$56.48 when purchased online
Target Online store #3991

About this item

Highlights

  • Depend Night Defense Adult Incontinence Underwear for Men, extra-large (44–54" waist), 48 count; Depend’s packaging and product may vary
  • Overnight Absorbency: Night Defense features a super absorbent core which absorbs 25x its weight* and turns liquid into gel, locking wetness in place for all-night comfort (*weight of super absorbent material)
  • Overnight Protection: Our men’s bladder leakage underwear delivers up to 12 hours overnight protection for heavy bladder leaks
  • 2x Drier Than Before: Depend’s improved liner wicks wetness away from your skin to help keep you dry
  • Odor Control: Our overnight underwear for bladder leaks helps neutralize and lock in odors by turning liquid into gel
  • Comfort: Depend Night Defense is unlike bulky adult diapers and features a discreet fit with soft, smooth fabric
  • Secure Fit: Depend Night Defense has a high-performance waistband to help keep your underwear securely in place
  • Depend adult incontinence underwear for men are HSA/FSA-eligible in the US

Description

Sleep through the night with Depend Night Defense Adult Incontinence Underwear for Men with Overnight Absorbency, providing up to 12 hours of protection. Available in a classic grey color, this disposable underwear is unlike bulky adult diapers and is ideal for bladder incontinence for nighttime use. Our bladder leak underwear features a super absorbent core that absorbs 25x its weight* and turns liquid into gel, helping neutralize odors and locking wetness in place. Depend’s liner is 2x drier than before and helps keep you dry all night by wicking wetness away from your skin. Depend bladder leakage underwear for men provides a discreet fit, soft and smooth fabric, and a high-performance waistband that helps keep underwear securely in place and helps you sleep worry-free. Depend Night Defense incontinence underwear for men is available in three sizes: size small/medium (26–34" waist), size large (35–43" waist) and size extra-large (44–54" waist). Packaging may vary from images shown. Some more good news: This product is HSA/FSA-eligible in the U.S. (*weight of super absorbent material)
Health Facts: No Fragrance Added
Disposability: Do not flush
Absorbency: Overnight
Package Quantity: 48
Number of units per package: 48
Minimum Waist Size: 44 Inches
Maximum Waist Size: 54 Inches
Features: Leak Protection, Nighttime Use, Disposable
TCIN: 87937521
UPC: 036000551624
Item Number (DPCI): 245-01-2185
Origin: Assem In USA w/ foreign parts
If the item details above aren’t accurate or complete, we want to know about it.

Allergens & Warnings:

WARNING: TO AVOID DANGER OF SUFFOCATION, KEEP THIS PLASTIC BAG AWAY FROM BABIES AND CHILDREN. DO NOT USE THIS BAG IN CRIBS, BEDS, CARRIAGES OR PLAY PENS. LIKE MOST ARTICLES OF CLOTHING, UNDERWEAR CAN BURN IF EXPOSED TO FLAME OR OTHER SOURCE OF IGNITION.

Shipping details

Estimated ship dimensions: 12 inches length x 18.25 inches width x 9.625 inches height
Estimated ship weight: 7.8 pounds
We regret that this item cannot be shipped to PO Boxes.
This item cannot be shipped to the following locations: American Samoa (see also separate entry under AS), Guam (see also separate entry under GU), Northern Mariana Islands, Puerto Rico (see also separate entry under PR), United States Minor Outlying Islands, Virgin Islands, U.S., APO/FPO

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Q: Can these be worn all day

submitted by Nana - 3 years ago
  • A: Hi Nana, our Night Defense Underwear provides protection from bladder leaks for up to 12 hours. We hope this helps!

    submitted byDependExpert - 3 years ago
    Brand expert
  • A: yes it can . it obsorbs a lot of urine.

    submitted bydiaper boy - 2 years ago

Q: Has the absorpency formula for the Night Defense Depense been changed recently? My husband has had, within the past 2 months, multiple leaking issues with this product.

submitted by Caretaker Wife - 25 days ago
  • A: We're sorry to hear about your husband's recent experience with our Depend Night Defense Underwear. We'd like the opportunity to learn more to see how we can help. Please give us a call at 1-877-413-3736 (Monday–Friday from 8am-5pm CST). We hope to hear from you soon.

    submitted byDependExpert - 24 days ago
    Brand expert

Q: Will the diaper contain bowel incontinence

submitted by Tony - 6 months ago
  • A: Hi Tony. Our Depend® products are designed and tested for urinary incontinence, not bowel incontinence. Thank you for reaching out, and we hope this helps!

    submitted byDependExpert - 6 months ago
    Brand expert

Q: What is the proper way to put on night defense depends

submitted by Max - 7 months ago
  • A: Hi Max! Depend Night Defense is designed to look and feel like underwear. They do not have tape fasteners, so you can easily slip them on.

    submitted byDependExpert - 7 months ago
    Brand expert

Q: i want to order 7 of these diapers plus CaDCADE DISHWASHING DETERGENT

submitted by MARGARET - 3 years ago
  • A: Hi MARGARET, please reach out to Target directly for the best assistance at 1 (800) 440-0680. Thank you.

    submitted byDependExpert - 3 years ago
    Brand expert

Q: what size depends for 38" waist

submitted by OZ - 3 years ago
  • A: Thank you for your question. Our Depend Night Defense in size large is for pant sizes 35-43. We hope this helps!

    submitted byDependExpert - 3 years ago
    Brand expert

Q: what is the waist size for S/M?

submitted by JCLAYTON - 4 years ago
  • A: Thanks for your question. The waist measurements for our S/M underwear is 31-37in. We hope this helps.

    submitted byDependExpert - 4 years ago
    Brand expert

Depend Incontinence Essentials for Men Collection

Depend Incontinence Essentials for Men Collection

About the collection
Depend Incontinence Essentials for Men
Depend is helping people get back to what matters most. Feel confident with Depend Fit-Flex—protective, disposable underwear for everyday bladder incontinence. Manage bladder leaks big and small with maximum-absorbency pads, Depend Guards, and light-absorbency pads, Depend Shields. Say goodbye to bulky adult diapers and say hello to Depend Real Fit, Depend men's softest, smoothest underwear. Plus, rest easy with Depend Night Defense, bladder leakage underwear that offers overnight absorbency. Explore our collection for more!

View Depend Incontinence Essentials for Men Collection collection

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Related Categories

4.5 out of 5 stars with 848 reviews
comfort: 4.39 out of 5
effectiveness: 4.16 out of 5
quality: 4.29 out of 5
value: 4.14 out of 5
80% would recommend
61 recommendations

Cant they make them WHITE or a LIGHTER color??

3 out of 5 stars
Thumbs down graphic, would not recommend
Elon - 5 days ago, Verified purchaser
These Depends are too dark in color when a patient or any individual for that matter, is wearing light colored clothes. What happened to white ones?? My patient insisted on beige-white shorts but you can see the gray Depends thru the shorts. I could not find white ones that were PULL-UPS. So what's the problem with the dark colors. It's very troubling when someone makes fun of seeing his Depends.
comfort: 4 out of 5
effectiveness: 3 out of 5
quality: 4 out of 5
value: 4 out of 5
Did you find this review helpful?

Stops leaks!

5 out of 5 stars
gregoryl16_4015 - 16 days ago
originally posted on influenster.com
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[This review was collected as part of a promotion.] It does what it needs to prevent overnight leaks. Doesn’t leave an odor and is very absorbent. Fits comfortably as well. Feels safe wearing these at night.
Did you find this review helpful?

Good one when you need

4 out of 5 stars
duyn15_9786 - 16 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] I’ve been using Depend products, specifically the Fit-Flex Incontinence Underwear for Men, for a few months, and they’ve been a game-changer. The fit is snug yet comfortable, with elastic bands that hug the body without feeling restrictive. They’re discreet under clothing, which gives me confidence during daily activities. The absorbency is impressive—handling moderate leaks effectively with Dryshield Technology, keeping me dry and odor-free all day. I also appreciate the variety of sizes; the size chart was spot-on for my measurements (32-inch waist, size S/M). The material feels soft, not bulky like some competitors, and they’re easy to slip on and off. However, I’ve noticed occasional bunching in the crotch area after extended wear, which can be slightly uncomfortable. Overall, Depend offers reliable protection and peace of mind, making them a solid choice for managing incontinence. I’d recommend them to anyone seeking comfort and discretion.
Did you find this review helpful?

Good product

5 out of 5 stars
tramn58_215 - 19 days ago
originally posted on influenster.com
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[This review was collected as part of a promotion.] Used it for my nephew and it worked well for him. No leaking and good absorbency. He really likes it and said that it was more comfortable than products that he has been using.
Did you find this review helpful?

Great durable underwear.

5 out of 5 stars
santiagoc53_8475 - 19 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] These are so comfortable, durable & absorbent. No odor escapes them whatsoever. I work in the crafts & had no problems. Overall a really good product.
Did you find this review helpful?

Night defense for elderly

5 out of 5 stars
sweetk2_1251 - 19 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] I'm quite impressed by the ability to absorb liquid with no leak and almost no odor in the morning. Size perfect snug, no irritation or leaves mark, and very comfortable.
Did you find this review helpful?

Works great when you have that worry!

5 out of 5 stars
chancew5_1997 - 20 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] Worked great when the time came to put them on. The fit and finish on them is second to none and they made it through the night with no concerns of leaking or foul odor…would buy again!
Did you find this review helpful?

Looks big, but fits great and eases worries.

4 out of 5 stars
travisp21_9651 - 20 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] My first thought was that these look big and bulky. But once you put them on they are comfortable. The leak protection is great, you don’t have to worry about little leaks because the absorbency is top quality with the dryshield and the odorblock gives that extra sense of relief. If you have small leaks in the middle of the night, I recommend this product.
Did you find this review helpful?

Good pack

5 out of 5 stars
saifulh_3552 - 21 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] Great pack. There is coverage in the front and back so there is no leakage. Not too thick so that it’s uncomfortable either. Good and comfortable fit if you know your size
Did you find this review helpful?

Great look and feel

5 out of 5 stars
dank45_1247 - 21 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] These feel great and have a nice soft outer fabric. Very comfortable and they look nice too. Excellent on leak protection and look like underwear.
Did you find this review helpful?

Comfortable and effective

5 out of 5 stars
stevens144_2966 - 22 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] Works as expected! I was told it provides leak protection overnight and is quite comfortable. Would recommend. Sizing on the package is accurate
Did you find this review helpful?

Very dependable.

5 out of 5 stars
davidg88_6971 - 22 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] I received the Depend reusable men’s large underwear free of charge in exchange for my honest review. I used this reusable underwear when I got sick from stomach bug and was not able to hold myself. The underwear, were very comfortable, odor free, they perfectly fit and the absorbency is amazing, very comfortable and durable. I really like this reusable underwear. Thanks to my wife again for always thinking ahead of time and always carries this kind of staff to be prepared for any situation. Thank you @influenster and @depend
Did you find this review helpful?

Damp, Not Dependable

3 out of 5 stars
an257_1806 - 22 days ago
originally posted on influenster.com
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[This review was collected as part of a promotion.] Depend Night Defense Underwear for Men falls short when it comes to reliable overnight protection. The back absorbent zone is too short, so sleeping on your back often leads to leaks. With no internal leak guards, heavier flow can wick through to clothing and bedding, leaving you damp by morning. I consistently woke up soggy, and urine seeped through into my pants.
1 reply from Depend Customer Service team - 21 days ago
We're sorry to hear about your recent experience. We'd like the opportunity to learn more, and to see how we can help. Please give us a call at 1-877-413-3736 (Monday–Friday from 8am-5pm CST). We hope to hear from you soon.
Did you find this review helpful?

Overnight piece of mind

5 out of 5 stars
jerryh12_2436 - 22 days ago
originally posted on influenster.com
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[This review was collected as part of a promotion.] Received men’s Depends free to trial. Very good fit. Easy to slide on and off. Very absorbent and no leaking. Comfortable to wear and keeps you dry overnight. If you have any bladder issues, even occasionally, great product to have.
Did you find this review helpful?

Great for the money

5 out of 5 stars
ohitsme99_4476 - 23 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] Has very good leak protection guards as well as very comfortable and it fits well. Great order control. Also the absorbency was the perfect type for me. I will definitely be buying. I like how they feel like underwear very discreet as well.
Did you find this review helpful?

The fit of the underwear

5 out of 5 stars
timothym65_8369 - 24 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] Fits perfectly and feels great like actually underwear and no leaks in the underwear. The odor control is no smell. The absorbency feels great.
Did you find this review helpful?

Great underwear

5 out of 5 stars
al154_460 - 26 days ago
originally posted on influenster.com
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[This review was collected as part of a promotion.] Very good for use at night when accidents happen. Felt comfortable and provided defense against leaks and smells. It fit well as well and didn’t slip.
Did you find this review helpful?

Great protection all night!!!!

5 out of 5 stars
marcust26_2108 - 26 days ago
originally posted on influenster.com
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[This review was collected as part of a promotion.] The Night Defense Depends are comfortable and provide great protection. They are very absorbent and control odors perfectly. I love how they fit without causing any problems.
Did you find this review helpful?

Comfortable, Highly Absorbent, and Versatile

5 out of 5 stars
ryank70_2985 - 26 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] In my book, disposable underwear need to be comfortable, highly absorbent and flexible enough to move with the body during activity. I was sent this product complimentary by Influenster in exchange for only an honest and unbiased review. After testing them out over a few weeks, I’ve found that this variety checks all the boxes. It can hold a huge amount of liquid without leaking or flowing over the sides. They are easy to pull on and off, and the elastic is stretchy enough to accommodate a few extra pounds, or to prevent them from falling down if they are a bit large. Just a note, you can also cut or easily tear apart the sides to remove them without pulling them down over your feet.
Did you find this review helpful?

Comfortability

5 out of 5 stars
donh17_440 - 26 days ago
originally posted on influenster.com
Image
[This review was collected as part of a promotion.] This product is unbelievably comfortable and the fit is perfect. I haven’t had any issues regarding leaking because of the great absorbency. I’ve yet to find any odor issues. I am extremely pleased with this product.
Did you find this review helpful?

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