Differin Adapalene Gel 0.1% Acne Treatment - 15g

Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 1 of 4Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 2 of 4Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 3 of 4Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 4 of 4
Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 1 of 4
$14.99When purchased online

About this item

At a glance

No Synthetic Fragrance
No Synthetic Fragrance
HSA/FSA Eligible
HSA/FSA Eligible
Oily Skin
Oily Skin
Dermatologist Tested
Dermatologist Tested
Combination Skin
Combination Skin
Acne-Prone Skin
Acne-Prone Skin

Highlights

  • Clear and prevent acne with an Rx-strength retinoid
  • Fights the main causes of acne by regulating skin cell turnover & reducing inflammation deep in the skin to clear and prevent pimples, blackheads and clogged pores
  • Differin Gel can reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998, Galderma Laboratories)
  • Effectively treats acne to restore your skin's natural tone & texture
  • The retinoid in Differin heals current acne and stops new acne from forming

Specifications

Scent: Unscented

Health Facts: Dye-Free, Contains Retinoids, Phthalate-Free, Aluminum-Free, No Fragrance Added

Product Form: Gel

Beauty Purpose: Spot Treatment

Recommended Skin Type: Oily, Acne-Prone, Combination

Net weight: 15 Grams

Features: Dermatologist Recommended, Dermatologist Tested

TCIN: 51346324
UPC: 302994920303
Item Number (DPCI): 037-12-0197
Origin: Assem USA w/foreign/dom. parts
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.

Description

Unlike other acne treatments you can buy in stores, Differin contains the first OTC Rx-strength acne-fighting retinoid. Retinoids play a crucial role in the treatment of acne by regulating skin cell turnover & reducing inflammation deep in the skin to clear & prevent pimples. What makes the retinoid in Differin (Adapalene) so cool is that, unlike other topical prescription retinoids, Differin is gentler on your skin, while still effective — and you don’t have to do things like completely avoid sunlight forever!

Then apply a thin layer of Differin Gel once every day all over your face — even when you’re not breaking out. Differin Gel might take a few weeks to start to work, and during this time, you could experience some dryness and irritation while your skin gets ready for gorgeous. The retinoid in Differin Gel may take a few weeks to work, and it may seem like it’s getting a little worse before it gets better. But, like your old track coach used to say, “You just gotta push through it!”

When used every single day, Differin Gel can reduce up to 87% of acne in just 12 weeks. That’s about the time it would take to leisurely binge-watch your favorite old TV series.

No Synthetic Fragrance
A product that either makes an on-pack statement indicating that it does not contain synthetic fragrance, or carries an unqualified on-pack statement "no fragrance".
HSA/FSA Eligible
Restrictions apply; contact your insurance provider about plan allowances and requirements
Oily Skin
Recommended for Oily Skin.
Dermatologist Tested
Dermatologist tested product.
Combination Skin
Recommended for Combination Skin.
Acne-Prone Skin
Recommended for Acne-Prone Skin.
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If the item details above aren’t accurate or complete, we want to know about it.

Active ingredients

adapalene (retinoid)* 0.1%

Purpose

Acne treatment

Uses

Use For the treatment of acne

Directions

Directions Adults and children 12 years of age and older: use once daily clean the skin gently and pat dry before applying the product cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. do not use more than one time a day. Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age: ask a doctor

Other information

Other information store at room temperature 68°-77°F protect from freezing

Inactive ingredients

carbomer 940, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide. may contain hydrochloric acid to adjust ph.

Shipping details

Estimated ship dimensions: 6.4 inches length x 2.7 inches width x 1.93 inches height
Estimated ship weight: 0.08 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Q: Can this be mixed with niacinamide or benzoyl peroxide?

submitted by - 2 years ago
  • A: While tretinoin is unstable and cannot be used with benzoyl peroxide, adapalene is stable and can be used with benzoyl peroxide. A combination medication is actually available by prescription (Epiduo). While they can be combined, sometimes benzoyl peroxide is too irritating when used with Differin. Because benzoyl peroxide can bleach pillowcases, some people apply Differin at night and benzoyl peroxide in the mornings. Benzoyl peroxide is available in different strengths, so ask your physician or start with one of the lower concentrations to reduce the chances of irritation.

    submitted byAnonymous - 2 years ago
  • A: I was told by my dermatologist that benzoyl peroxide and retinoids basically cancel each other out.

    submitted byIlovetarget - 2 years ago
  • A: Hi @tropical. Thanks for your question. Generally we do not recommend mixing Differin Gel with other active ingredients, however we would recommend checking in with your dermatologist who can provide guidance for your unique skin! Hope this helps. Thanks

    submitted byGalderma Team Member - 2 years ago
    Brand expert

Q: I currently use a salicylic acid cleanser, benzoyl peroxide gel (5%), and a moisturizer day and night for light/moderate acne. How do I add this to my current routine?

submitted by tmg - 5 years ago
  • A: According to the manufacturer of this drug they do not recommend that you use any type of other active ingredients that contain AHA or BHA or Glycolic acids while using Differn Gel. In my opinion, I would let your skin acclimate to Differn for at least 2-3 months and maybe do a few test patches with your favorite products before jumping in full throttle. I can sympathize with you, I just started Differn 2 weeks ago and I hated to give up my favorite gylcolic acid toner and BHA serum, but so far I am seeing far superior results with Differn alone on my stubborn blackheads that have pestered me since my teens and I’m in my mid 40’s. My complexion is also improving in tone and texture as well. Hope this helps!

    submitted byBeachbride322 - 4 years ago
  • A: I agree with the other responses, and I'd like to add that if you're currently using AHA or BHA or benzyl peroxide products currently, give your skin a break for about a week before using any retinoid product such as Differin. And I would also not recommend using any other chemical or physical exfoliant products while you use a retinoid if you have sensitive skin, otherwise you run the risk of burning your skin or really irritating it and causing redness.

    submitted byavkayes - 3 years ago
  • A: Hi, tmg. Differin Gel is more than just a spot treatment so we recommend applying this product daily to stop new acne from forming.To limit skin irritation or flakiness, try switching to hydrating cleansers every other day to keep skin moisturized during treatment. Hope this helps!

    submitted byTarget Beauty Concierge - 5 years ago
    Brand expert

Q: Would this work as a spot treatment?

submitted by bb1342 - 2 years ago
  • A: Actually, retinoids are not to be used as spot treatments. They take time to work and are most effective when consistently used over periods of time. More appropriate spot treatments would be benzoyl peroxide or salicylic acid.

    submitted byAnonymous - 2 years ago
  • A: Hi bb1342! This is a fantastic spot treatment. Hope this helps!

    submitted byTarget Beauty Concierge - 2 years ago
    Brand expert

Q: is this good for normal to dry sensitive skin?

submitted by Briana - 3 years ago
  • A: Differin OTC is the lowest concentration available, and Differin is considered to be the gentlest retinoid. A cream version is available by prescription that some people find more suitable for dry skin. You could also try layering Differin with a gentle moisturizer, whether under or over the Differin. It may be a matter of trial and error.

    submitted byAnonymous - 2 years ago
  • A: Hi Briana! This Acne Treatment works well with all skin types, including dry, sensitive skin types! Adapalene is a gentle acne treatment. Hope this is helpful!

    submitted byTarget Beauty Concierge - 3 years ago
    Brand expert

Q: What comes in the container because I think something is missing out of it?

submitted by Keya - 4 years ago
  • A: the box is weird, it looks likes something is missing because of all the extra space inside, but its just the bottle, its not missing anything...

    submitted bygoodkine - 2 years ago
  • A: Hi Keya! This will contain a 15mg tube of the Different Acne Treatment Gel. Hope this helps!

    submitted byTarget Beauty Concierge - 4 years ago
    Brand expert

Q: Does this help teens also or only adults

submitted by I need help acne - 5 years ago
  • A: Hi there. Differin Gel has been approved for anyone 12 years and older with mild to moderate acne. If you have severe acne, we recommend speaking with your doctor before using. Hope this helps!

    submitted byTarget Beauty Concierge - 5 years ago
    Brand expert
  • A: I would certainly give this a go before going to see a dermatologist for your teen. Chances are it will help improve the acne, and if it doesn't, you're only out $14 and your teen's skin will have ready had time to acclimate to using prescription strength retioniods. Retin A/ Tretinoin is much stronger and the side effects are brutal in the beginning, some people give up because of the peeling and irritation.

    submitted byBeachbride322 - 4 years ago

Q: Although I have an occasional pimple, acne is not a main concern of mine. I have dark spots from sun damage... will this product help if I apply vitamin C serum over it?

submitted by artful - 5 years ago
  • A: I'm in my mid 40’s and have the same issues with my skin as you but add a million blackheads to it and so far, I am loving the results! Just after two weeks my blackheads and whiteheads are disappearing rapidly, sunspots are fading, and the all over improvement of texture is unbelievable! I will continue using for at least 6 more months before I make a decision on whether or not it is effective on deeper wrinkles, as these medications take time to see full results. But so far, I am blown away!

    submitted byBeachbride322 - 4 years ago
  • A: Hi, Artful. This product is a prescription strength acne medication that specifically targets pimples, blackheads, and whiteheads. Since your main concern is dark spots, we recommend opting for a serum that contains retinol, which will improve skin texture and fade dark spots over time. Hope this helps!

    submitted byTarget Beauty Concierge - 5 years ago
    Brand expert

Q: Does this also help with black spots on your face due from acne?

submitted by Lala - 6 years ago
  • A: If you're speaking of blackheads, yes! I have had very stubborn blackheads that completely cover my nose, chin and a some scattered throughout my cheeks. I also have whiteheads that nothing else works on. This is a miracle product on blackheads! Only 2.5 weeks since initial application and I can see a visible difference. They are finally giving way little by little and are waaay less visible!

    submitted byBeachbride322 - 4 years ago
  • A: Yes, the active ingredient in Differin also targets dark spots and scars left behind from acne (post-inflammatory hyperpigmentation).

    submitted byskingenie - 6 years ago

Q: Can anyone tell me if this is vegan? Thank you.

submitted by JudyBeauty - 2 months ago
  • A: Hello Judy, the Differin Adapalene Gel 0.1% Acne Treatment is considered vegan but is dye-Free, contains Retinoids, Phthalate-Free, Aluminum-Free, and has no fragrance added. For all your future beauty questions, get real-time answers using the “Chat with a Virtual Beauty Consultant” button, found on every product page :)

    submitted byTarget Beauty Consulting - 2 months ago
    Brand expert

Q: can Organic Jojoba Oil balancing face oil for oil skin types be used as a moisturizer when using the Differin Adapalene Gel 0.1% acne treatment 15g?

submitted by DJ - 1 year ago
  • A: Hello DJ! If you have oily skin, try using it every other day or mix it in with your favorite Differin moisturizer to avoid overdrying.

    submitted byTarget Beauty Consulting - 1 year ago
    Brand expert
4.7 out of 5 stars with 2875 reviews
90% would recommend
250 recommendations
Treats Spots: 4.82 out of 5
Improves Skin Texture: 4.74 out of 5
Accurate Scent: 4.78 out of 5

Not the Vibe for Hormonal Acne

2 out of 5 stars
Would not recommend
cbrown - 2 days ago, Verified purchaser
I have hormonal and cystic acne (shoutout PCOS), and this didn’t help my skin at all. I had heard it was a good option and to try it before using prescription-grade products, but this didn’t help or hurt my existing acne.
Accurate Scent: 5 out of 5
Treats Spots: 2 out of 5
Improves Skin Texture: 2 out of 5
1 guest found this review helpful. Did you?

Amazing stuff

5 out of 5 stars
Would recommend
Valerie - 6 days ago, Verified purchaser
A pea sized amount every night changed my skincare routine completely. My fungal acne on my forehead is gone, my pores are smaller, I don't get pimples anymore (this is after consistent use, your skin will break out and purge the first few weeks you use this stuff), and my skin is so much more radiant. I'm so glad I trusted the process and pulled through the purging/dry skin phase of it!!! So worth it!!!
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
Improves Skin Texture: 5 out of 5
Did you find this review helpful?

Absolutely amazing

5 out of 5 stars
Would recommend
Reviewsfordays - 17 days ago, Verified purchaser
Holy grail acne product especially for the price! It took a little while for it to start working but once it did it definitely lessened new acne and past acne.
1 guest found this review helpful. Did you?

Helping with my postpartum acne

4 out of 5 stars
Would recommend
AML - 22 days ago, Verified purchaser
Some slight stinging at first. I recommend starting with use once a week and increasing as your skin adjusts. Love that I have this product for my postpartum acne!
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
Improves Skin Texture: 4 out of 5
1 guest found this review helpful. Did you?

i love this product

5 out of 5 stars
nermeen16 - 1 month ago
originally posted on influenster.com
so i hopped onto the skin cracking trend from tiktok because i was seeing amazing results and nothing was working to maintain my stress breakout. i’ve been using this product on day 2: retinol for three weeks now and all i can say is i’m speechless. i didn’t expect this stuff to work so well. i usually see results just over night which is crazy! will definitely stick to this routine for the rest of me life.
6 guests found this review helpful. Did you?

Good

4 out of 5 stars
Would recommend
Review - 1 month ago, Verified purchaser
For the price it’s been okay. I applied small amounts on the blemished skin. Not clear yet but it’s controlled. It takes time but not bad for the price (on sale)
Treats Spots: 4 out of 5
Accurate Scent: 4 out of 5
Improves Skin Texture: 4 out of 5
Did you find this review helpful?

Like it!

5 out of 5 stars
Would recommend
Shiny94 - 2 months ago, Verified purchaser
This product has been working really well on my skin. It's gentle enough to use everyday. I have seen big improvements on skin especially the blackheads. I will definitely be purchasing again.
4 guests found this review helpful. Did you?

Amazing product

5 out of 5 stars
Makayla - 2 months ago, Verified purchaser
This is the ONLY product that has cleared my acne completely
6 guests found this review helpful. Did you?

Acne

5 out of 5 stars
Would recommend
Diana - 2 months ago
This product did the magic on my skins and clear my acne and blemishes area of my skin it’s very soft and it’s really good product to buy it
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
Improves Skin Texture: 5 out of 5
4 guests found this review helpful. Did you?

Wish I found this 20 years ago

5 out of 5 stars
Would recommend
Happy Shopper - 2 months ago, Verified purchaser
I think it does what it says it will. Fixes all of the above.
5 guests found this review helpful. Did you?

A little goes a

4 out of 5 stars
nicoleh481 - 2 months ago
originally posted on influenster.com
A little goes a long way. Make sure you take recovery days for your skin because this stuff is powerful and as effective of a retinoid as its pricier counterparts. I wish I started using this stuff sooner. The texture is a little stickier than other retinoids but I don't mind it. It dries well and doesn't pill under moisturizer. Great product!
1 guest found this review helpful. Did you?

Works Great!

5 out of 5 stars
Would recommend
AutumnDee - 2 months ago, Verified purchaser
I’ve been using this product for the past 2 weeks and the difference in my skin is night and day. My pimples are almost fully gone and I have no more protruding bumps! I use this along with the Differin dark spot correcting serum and the results have been fantastic! It’s become apart of my nightly skin care routine!
Accurate Scent: 3 out of 5
Treats Spots: 5 out of 5
Improves Skin Texture: 5 out of 5
4 guests found this review helpful. Did you?

Works but requires PATIENCE

5 out of 5 stars
Would recommend
Bees - 2 months ago, Verified purchaser
This works but you have to be patient. It takes at least a few weeks, it took several for me, and you need to put it on your whole face, not just where you have a breakout. I’m on week 10, I normally break out horribly before my period, but last month I only had one pimple. This also helped clear a couple really deep stubborn blackheads. I’ve used retin-a before, which works faster but also made me super peel-y and dry. This works a lot slower but is much gentler on your skin. Combining it with niacinamide and vitamin c products has finally made a difference with old acne scars and texture too, though maybe not quite as much as I had hoped. I might need to see an esthetician for more dramatic results with that. But my breakouts are pretty much totally under control now. Just give it time to work and do it’s thing and you’ll be pleasantly surprised.
Treats Spots: 5 out of 5
Accurate Scent: 5 out of 5
Improves Skin Texture: 4 out of 5
8 guests found this review helpful. Did you?

It's a miracle!

5 out of 5 stars
Avda - 2 months ago
originally posted on differin.com
Been using the gel 5 months. Suffered from adult painful cystic acne. After 1 month of nightly use 50% improvement, after 2 month 75% improvement, after 3 months 100% clear skin. I now use it every other night because it has also made the texture of my skin smooth as a baby's behind & the pores on my nose & face are a lot smaller. If I feel even one cyst starting I go back to every night application until it is gone. If you suffer from acne make the 3 month commitment to try it & don't give up!
15 guests found this review helpful. Did you?

Works great

5 out of 5 stars
Would recommend
Hina - 2 months ago, Verified purchaser
This stuff is effective for my oily skin and this really helps clear up my pimples & tiny bumps and it has now become a daily part of my sensitive skin routine. Definitely worth buying
Treats Spots: 5 out of 5
4 guests found this review helpful. Did you?

One of the best over the counter

4 out of 5 stars
laurenm623 - 2 months ago
originally posted on influenster.com
This is one of the best over the counter treatments. I have hormonal acne and this helped. It does dry out your skin so make sure you moisturize it.
4 guests found this review helpful. Did you?

Good

4 out of 5 stars
avag74 - 3 months ago
originally posted on influenster.com
Just started using this and on the first day I already notice a change to my acne. I’m hoping to use this more and I’m looking forward to clearing my skin up
2 guests found this review helpful. Did you?

Game changer

5 out of 5 stars
sommerr4 - 3 months ago
originally posted on influenster.com
This helped cleared my complexion within two months! I am super happy with the results it gave me, & this is going to become a staple in my skincare routine from now on. Give this a try!
7 guests found this review helpful. Did you?

I feel like my

5 out of 5 stars
sarahchungmalmstrom - 3 months ago
originally posted on influenster.com
I feel like my skin is improved the morning after using it the previous night. I use a pea sized amount about twice a week, and I love that it helps with anti aging as well as my minor acne that pop up now and again. One tube lasts a long time and it spreads well also.
8 guests found this review helpful. Did you?

holy grail acne product

5 out of 5 stars
Would recommend
candacel97 - 3 months ago, Verified purchaser
I never write reviews but this stuff is amazing! i was using tretinoin and my skin was just getting worse, but after using differin two nights in a row i now have almost clear skin. (one or two left that are still under the skin) get it!!!
Improves Skin Texture: 5 out of 5
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
11 guests found this review helpful. Did you?

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