Sponsored
Excedrin Migraine Pain Reliever Caplets - Acetaminophen/Aspirin (NSAID)
$12.99 ($0.13/count)
In Stock
Eligible for registries and wish lists
At a glance
Sponsored
About this item
Highlights
- One bottle of 100 Excedrin Migraine Caplets for Migraine Headache Relief
- Excedrin Migraine works in 3 ways to relieve migraines fast
- Provides migraine relief, including migraine headache pain, sensitivity to light and sound, nausea
- With acetaminophen and aspirin as pain relievers, and caffeine to enhance their analgesic effect
- Delivers a powerful triple action formula with two pain relievers and an amplifier
- HSA and FSA eligible product
Description
Excedrin Migraine Caplets for Migraine Headache Relief provide migraine relief fast, making Excedrin Migraine the #1 neurologist recommended OTC treatment for migraines.* Excedrin works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect. Available in convenient caplet form, this powerful migraine medicine delivers a specialized triple action formula containing two pain relievers and an amplifier. These Excedrin caplets combine aspirin and acetaminophen with caffeine to provide migraine relief, including migraine headache pain, sensitivity to light and sound, and nausea. For some, this migraine headache medicine starts relieving migraine pain in 30 minutes. Get migraine relief fast with Excedrin, the headache expert.
*Among OTC medicine for migraines IQVIA, Inc., 2018
*Among OTC medicine for migraines IQVIA, Inc., 2018
Suggested Age: 12 Years and Up
Health Facts: Contains Aspirin, Contains Acetaminophen
Active Ingredient Strength Value: 250 Milligrams
Product Warning: Keep out of reach of children
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 100
Net weight: 3.46 Ounces
TCIN: 11009981
UPC: 300672039835
Item Number (DPCI): 094-01-0235
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.
Active ingredients
acetaminophen(250mg), aspirin (nsaid)(250mg), caffeine(65mg).
Purpose
Pain Reliever, Pain Reliever, Pain Reliever Aid..Allergy alert: Aspirin may cause a severe allergic skin reaction which may include:
Allergy alert: Aspirin may cause a severe allergic skin reaction which may include:: hives,facial swelling,asthma (wheezing),shock.Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 2 caplets in 24 hours, which is the maximum daily amount,with other drugs containing acetaminophen,3 or more alcoholic drinks every day while using this product.Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you
Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you: are age 60 or older,have had stomach ulcers or bleeding problems,take a blood thinning (anticoagulant) or steroid drug,take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others),have 3 or more alcoholic drinks every day while using this product,take more of for a longer time than directed.Do not use
Do not use: if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer,with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.Ask a doctor before use if
Ask a doctor before use if: you have never had migraines diagnosed by a health professional,you have a headache that is different from your usual migraines,you have the worst headache of your life,you have fever and stiff neck,you have headaches beginning after or caused by head injury, exertion, coughing or bending,you experienced your first headache after the age of 50,you have daily headaches,you have a migraine so severe as to require bed rest,you have liver disease,stomach bleeding warning applies to you,you have a history of stomach problems, such as heartburn,you have high blood pressure, heart disease, liver cirrhosis, or kidney disease,you are taking a diuretic,you have asthma,you have problems or serious side effects from taking pain relievers or fever reducers,you have vomiting with your migraine headache.Ask a doctor or pharmacist before use if you are
Ask a doctor or pharmacist before use if you are: taking a prescription drug for: diabetes; gout; arthritis,under a doctor's care for any serious condition,taking any other drug,taking any other product that contains aspirin, acetaminophen, or any other pain reliever/fever reducer.Stop use and ask a doctor if
Stop use and ask a doctor if: an allergic reaction occurs. Seek medical help right away,you experience any of the following signs of stomach bleeding: feel faint; vomit blood; have bloody or black stools; have stomach pain that does not get better,you migraine is not relieved or worsens after first dose,new or unexpected symptoms occur,ringing in the ears or loss of hearing occurs.Directions
Do not use more than directed.Adults
Take 2 caplets with a glass of water. If symptoms persist or worsen, ask your doctor. Do not take more than 2 caplets in 24 hours, unless directed by a doctor.Under 18 Years of Age
Ask a doctor.Other information
Store at controlled room temperature 20 degrees - 25 degrees C (68 degrees - 77 degrees F). Close cap tightly after use. Read all product information before using. Keep this box for important information.Inactive ingredients
benzoic acid, carnauba wax, fd&c blue no. 1, hypromellose, light mineral oil, low-substituted hydroxypropyl cellulose, microcrystalline cellulose, polysorbate 20, povidone, propylene glycol, simethicone, sorbitan monolaurate, stearic acid, titanium dioxide
Question or comments?
800-468-7746Shipping details
Estimated ship dimensions: 6.25 inches length x 4.37 inches width x 2.32 inches height
Estimated ship weight: 0.67 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
Q: Is it film coated for easier swallowing?
submitted by Anne - 4 days ago
Frequently bought together
$22.49($23.75/fluid ounce)
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 333 ratings
Bestseller
$2.19($0.22/count)
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 9016 ratings
$7.99($0.07/count)
Get a coupon, $10 off a $20 purchase with a flu shot
4.4 out of 5 stars with 384 ratings
Highly rated
$3.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.8 out of 5 stars with 923 ratings
Guests also viewed
Highly rated
$12.99 - $20.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.8 out of 5 stars with 5529 ratings
Bestseller
$4.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 4861 ratings
Highly rated
$12.99($0.13/count)
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 7436 ratings
Highly rated
$12.99 - $20.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.8 out of 5 stars with 6166 ratings
Bestseller
$2.59 - $6.79
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 1471 ratings
Highly rated
$3.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.8 out of 5 stars with 923 ratings
Discover more options
Highly rated
$12.99 - $20.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.8 out of 5 stars with 6166 ratings
Highly rated
$12.99($0.13/count)
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 7436 ratings
Bestseller
$4.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 4861 ratings
Highly rated
$2.59 - $6.79
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 1471 ratings
$6.99($0.14/count)
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 142 ratings
Related Categories
Guests are saying
Excedrin Migraine is a highly effective over-the-counter medication that combines acetaminophen, aspirin, and caffeine to provide quick relief from migraines. Many guests appreciate its fast-acting formula, often reporting significant pain reduction within 30 minutes. The compact packaging makes it convenient for on-the-go use, and its affordability adds to its appeal. While some guests note potential stomach sensitivity, the overall consensus is that it is a reliable choice for managing migraine symptoms.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.8 out of 5 stars with 5529 reviews
quality: 4.71 out of 5
value: 4.6 out of 5
97% would recommend
36 recommendations
4 out of 5 stars
23 November, 2025
originally posted on influenster.com

Great migraine relief
[This review was collected as part of a promotion.] These Excedrin migraine relief meds are very helpful as I suffer from migraines at times. They immediately relieve my pain within 30 mins of taking the pills. Also, the caffeine in them is great to have because if you unable to get caffeine from coffee or a soda these come in handy especially if you traveling. I carry them in my purse because you never know when a migraine may come on. The storage container is a little big but has enough medication for its value.
5 out of 5 stars
23 November, 2025
originally posted on influenster.com

Excedrin
[This review was collected as part of a promotion.] Excellent medicine for migraine, it removes pain in a few minutes, does not cause nausea or heartburn, the pill is easy to swallow without any bad taste.
5 out of 5 stars
22 November, 2025
originally posted on influenster.com

Quick migraine relief
[This review was collected as part of a promotion.] Worked great for the aura migraines I occasionally get. It contains caffeine and I don’t usually use products with caffeine but after some research I learned caffeine is beneficial to migraine relief with acetaminophen and aspirin. However I haven’t taken it at night to know if the amount of caffeine = to 1 cup of coffee would keep me awake. No scent it’s a pill that is Odorless. The Instructions state you can only take 2 of these in a 24hr period unless directed by a doctor so that speaks to the strength of it. It comes in a standard headache medicine bottle
5 out of 5 stars
22 November, 2025
originally posted on influenster.com

Super fan!
[This review was collected as part of a promotion.] This is one of my favorite pain relievers for my migraines and the caffeine additive is so very helpful. I will always be the first to recommend Excedrin Migraine! It works super fast even when I first start to feel my migraine coming on and can keep it at bay to the point it doesn’t debilitate me! Child proof bottle is convenient and safe! Cannot recommend enough!
5 out of 5 stars
21 November, 2025
originally posted on influenster.com

Excelente
[This review was collected as part of a promotion.] Very good sensation, symptom relief quickly, results fast, excellent packaging, good frequency, it's very good for pains, it's very effective, I guarantee it
5 out of 5 stars
21 November, 2025
originally posted on influenster.com

Excedrin migraine relief
[This review was collected as part of a promotion.] This product acts very fast and relieves the pressure in no time. I just wish the pill was a little smaller. I can leave my normal life thanks to this product.
5 out of 5 stars
20 November, 2025
originally posted on influenster.com

Fast Relief When It Matters
[This review was collected as part of a promotion.] As someone who suffers from frequent migraines, I can tell you that Excedrin Migraine caplets are a lifesaver: they take about 30 to 40 minutes to kick in and help calm the pain quite effectively without making me feel too groggy. The packaging is simple a plastic bottle with 100 caplets and each caplet is easy to swallow. When they start to kick in, it feels like a gradual relief that reduces the pressure in my head and lessens my sensitivity to light, but it's not as harsh as some strong painkillers: it's a good balance between potency and comfort.
5 out of 5 stars
20 November, 2025
originally posted on influenster.com

Great!
[This review was collected as part of a promotion.] I often get migraines, and Excedrin Migraine is truly a lifesaver! Just one dose helps ease the pain quickly, and I feel relief fast. I trust it because it’s safe and easy to use—definitely a staple in my medicine cabinet.
5 out of 5 stars
19 November, 2025
originally posted on influenster.com

❤️
[This review was collected as part of a promotion.] Excedrin Migraine Relief has genuinely been a lifesaver for me. When a migraine hits, it usually takes over my whole day — the pressure, the throbbing, the sensitivity to every little sound. But this worked so fast I actually felt the pain start to fade within an hour. No drowsiness, no heavy feeling… just real, noticeable relief. I always keep it with me now because you never know when a migraine will strike, and I honestly can’t imagine dealing with them without this.
5 out of 5 stars
19 November, 2025
originally posted on influenster.com

Fast acting, effective relief to get you through t
[This review was collected as part of a promotion.] I highly recommend taking 2 of these for instant relief of that pounding migraine. I have consistently been able to rely on Excedrin as it's the only OTC medication that can relieve the intensity of migraine pain.
5 out of 5 stars
19 November, 2025
originally posted on influenster.com

Very effective
[This review was collected as part of a promotion.] The pills come in a very good size, the bottle is practical, and you can carry it anywhere. The dose is good for the migraine, easy to store and secure because of the child proof.
5 out of 5 stars
19 November, 2025
originally posted on influenster.com

Effective
[This review was collected as part of a promotion.] I felt the effect was faster than I expected, 100 caplets per jar, it’s 2 caplets with a glass of water every 24 hours. It worked for me and I would recommend it.
5 out of 5 stars
18 November, 2025
originally posted on influenster.com

A miracle
The only over the counter medication that relieves intense migraine pain in a matter of 20 minutes! It’s a miracle for me. The pill is small and easy to swallow. There is no smell. And the texture is perfect. Definitely recommend!
5 out of 5 stars
18 November, 2025
originally posted on influenster.com

Works every time
[This review was collected as part of a promotion.] Excedrin migraine is might go to for pain relief every single time I feel a migraine starting. It really is the only thing that works for me completely. Anything else I have to take more than the normal dosage, this I just take two And I know what's going to workm
5 out of 5 stars
17 November, 2025
originally posted on influenster.com

Best for migraines
[This review was collected as part of a promotion.] The perfect dosage for my migraines I have daily. It helps super fast and strong. There is no smell either and it's super pure! I highly recommend this for all your head ache worries
5 out of 5 stars
17 November, 2025
originally posted on influenster.com

A must have if u have migraines...
[This review was collected as part of a promotion.] Excedrin Migraine has been one of the few things that actually helps take the edge off when a migraine hits. It works pretty fast for me and helps calm the pain enough to get through the day. It’s definitely strong, so I only take it when I really need to, but it’s a solid go-to when those headaches get intense. 💊✔️
5 out of 5 stars
17 November, 2025
originally posted on influenster.com

It relieves my migraines quickly and without stron
[This review was collected as part of a promotion.] I've used Excedrin Migraine for several migraine episodes and it's worked quite well for me. The dosage is easy to follow, and the tablets have a smooth, soft texture, making them very easy to swallow without leaving a strange taste. In my case, relief starts 30–45 minutes after taking it and usually lasts for several hours. I haven't had any negative reactions, although I do recommend taking it with some food because it can feel a bit strong in the stomach. Overall, it helps me manage the pain and get back to my routine when a migraine is just starting.
5 out of 5 stars
17 November, 2025
originally posted on influenster.com

The best!
[This review was collected as part of a promotion.] This is my go to medicine when I have a migraine! I recommend it to everyone as it’s the only one that’s worked 100% of the time. I will say that they are slightly hard to swallow due to their size if you’re not good at handling larger pills though.
5 out of 5 stars
17 November, 2025
originally posted on influenster.com

Got a migraine? This works!
[This review was collected as part of a promotion.] For anyone who deals with migraines, you know that the moment you feel that first flicker of an aura or the dull throbbing start to set in, it’s a race against time. Excedrin Migraine isn't just a pain reliever for me; it's the emergency exit button that keeps my life from derailing entirely. I’ve tried countless over-the-counter pills, and none of them compare to the combination of acetaminophen, aspirin, and caffeine in this formula. The key, I’ve found, is catching the migraine early. If I take the recommended two caplets the second I sense that tell-tale pressure behind my eye or the onset of light sensitivity, it almost always nips the attack in the bud. The speed is what makes it so indispensable. Typically, within about 20 to 30 minutes, I can feel the pain start to recede. The intensity drops dramatically, and the nausea and sensitivity to light and sound that usually accompany my migraines become much more manageable. It’s the difference between functioning normally and spending the next six hours locked in a dark room.
5 out of 5 stars
16 November, 2025
originally posted on influenster.com

Very effective!
[This review was collected as part of a promotion.] This is my go to migraine relief medicine! Paired with something else it knocks out my migraine within 30 minutes! There’s no smell to them to me which is a plus! Easy to swallow as well! This medicine works wonders!