Sponsored
Oral-B iO Ultimate Clean Replacement Brush Heads
$29.99
In Stock
Eligible for registries and wish lists
Sponsored
About this item
Highlights
- You will receive 2 Oral-B iO Ultimate Clean Replacement Brush Heads
- Combines Oral-B's iconic round brush head with gentle micro-vibrations for a surprisingly enjoyable experience and healthy teeth and gums for life
- Reduces plaque build-up along the gumline
- The dual-length bristles surround and reach deep in-between teeth and have high density for an ultimate clean
- Compatible with Oral-B iO Electric Toothbrush Handles
- Dentists recommend changing your brush head every 3 months
Description
The Oral-B iO Series combines powerful, but gentle micro-vibrations with Oral-B's iconic dentist-inspired round brush head design for a professional clean feeling every day. Ultimate Clean Refills help remove plaque, leaving teeth feeling clean and bright. Tufted bristles help clean hard-to-reach areas of the mouth. Dentists recommend changing your toothbrush head every 3 months for best results. Do not use on children under age 3. Replace brush every 3 months or sooner if brush head becomes worn.
Suggested Age: 3 Years and Up
Product Warning: Not for children under the age of three
Package Quantity: 2
Industry or Government Certifications: ADA Seal of Acceptance
Material: Plastic
Features: Enamel-Safe
TCIN: 80267828
UPC: 069055128619
Item Number (DPCI): 049-11-0165
Origin: Made in the USA or Imported
If the item details aren’t accurate or complete, we want to know about it.
Shipping details
Estimated ship dimensions: 2.8 inches length x 9.3 inches width x 0.6 inches height
Estimated ship weight: 0.08 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
Frequently bought together
$8.99 - $9.99
$5 Target GiftCard with 4 select personal care
4.2 out of 5 stars with 3343 ratings
Bestseller
$4.99 - $12.99
$5 Target GiftCard with 4 select personal care
4.7 out of 5 stars with 21976 ratings
Bestseller
$9.99($2.50/count)
$5 Target GiftCard with 4 select personal care
4.2 out of 5 stars with 2081 ratings
Guests also viewed
See price in cart
$5 Target GiftCard with 4 select personal care
4.7 out of 5 stars with 496 ratings
See price in cart
$5 Target GiftCard with 4 select personal care
4.7 out of 5 stars with 319 ratings
$44.99
reg $59.94 - $59.99 Sale
4.4 out of 5 stars with 699 ratings
$29.99($5.00/count)
$5 Target GiftCard with 4 select personal care
4.9 out of 5 stars with 137 ratings
Discover more options
$24.99($12.50/count)
$5 Target GiftCard with 4 select personal care
4.7 out of 5 stars with 358 ratings
$18.94($9.47/count)
$5 Target GiftCard with 4 select personal care
4.8 out of 5 stars with 198 ratings
See price in cart
$5 Target GiftCard with 4 select personal care
4.7 out of 5 stars with 319 ratings
$34.99 - $39.99
Select items on sale
$5 Target GiftCard with 4 select personal care
4.6 out of 5 stars with 651 ratings
Related Categories
Guests are saying
The Oral B IO Ultimate Clean Refills are highly praised for their exceptional cleaning performance and comfort. Guests appreciate the gentle yet effective bristles that provide a thorough clean without irritating gums. The durability of each brush head, lasting up to three months, adds to their value. Many guests highlight the ease of installation and the hygienic packaging, making these refills a smart choice for maintaining optimal oral hygiene.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.7 out of 5 stars with 496 reviews
ease of use: 4.38 out of 5
quality: 3.63 out of 5
value: 2.25 out of 5
50% would recommend
10 recommendations
2 out of 5 stars
2 December, 2025Verified purchase
(no review title)
Item packaging, bent damage, crushed on side
1 reply from Oral-B team - 2 days ago
We're sorry to hear this was your experience, Bill. For assistance with your order, please reach out to Target at 1-800-440-0680.
2 out of 5 stars
27 November, 2025
originally posted on Oral-B
Poor
These brushes do not last a reasonable amount of time. I’m actually thinking they are defective with the colored bristles fading in the matter of 1-2 weeks. The unit itself is ok, way too slippery!!!! Poorly designed!
1 reply from Customer Care team - 7 days ago
We always want our consumers to know that they can rely on our products for their oral care routine, and we can understand the frustration with the bristles fading after a few weeks and the handle becoming slippery during use. All of our products are thoroughly tested to ensure their performance and ease of use, and this is not something we would expect. It is important to note that the bristles fading sooner than expected could be due to the amount of pressure used while brushing, or rinsing the brush under hot water. We would greatly appreciate a chance to learn more about your experience so we are better able to assist you as well as gather some additional information for our Quality Team, and encourage you to give us a call at (800) 566-7252.
5 out of 5 stars
23 November, 2025
originally posted on influenster.com

My teeth feel cleaner 💫
[This review was collected as part of a promotion.] Just restocked my Oral-B iO Ultimate Clean brush heads and honestly… game-changer every single time. ✨ The bristles are super soft but somehow deep clean like I just left the dentist. And I love that the color fades when it’s time to replace it, no more guessing. If you have the iO toothbrush, these refills make the biggest difference. My teeth feel smoother, cleaner, and way fresher. 🦷✨
4 out of 5 stars
19 November, 2025
originally posted on influenster.com

Okay
I have one right now I like it but there is better. It’s small brush the charge lasts good easy to use the pressure is good I would recommend as a start
4 out of 5 stars
Thumbs up graphic, would recommend
18 November, 2025Verified purchase
(no review title)
A little expensive. But get the job done better than a manual tooth brush.
1 out of 5 stars
Thumbs down graphic, would not recommend
27 October, 2025Verified purchase
Avoid!!
Horrible product! The design of this brush and the brush heads are impossible to clean and grows mold. Avoid this oral b product!!
1 reply from Oral-B team - 1 month ago
Meg, we can certainly imagine your surprise upon discovering mold in your brush head, and want to help. Please know that there’s nothing in our toothbrush components that would cause mold before use. Mold requires organic material to grow, which isn’t present in our brushes. While it’s rare, mold can develop after use if the brush is stored in a damp area or comes into contact with certain cleaning agents or soaps that can make the plastic porous. To help stop this from happening, we recommend cleaning your brush heads after each use. SO we can help further, please call us at (800) 566-7252.
1 out of 5 stars
Thumbs down graphic, would not recommend
20 October, 2025Verified purchase
The 4 pack don't seem legit
I usually by the 2 pack for $30, but saw the 4 pack for $34.95. The 2 pack usually last 3 months each or longer. I bought the 4 pack and just recently opened it. I changed the head on 9/19/2025. Exactly one month ago today. I now keep track of when they should be replaced. I included a picture. The one on the left is from the 2 pack after 2-3 months. The one on the right is after 1 month and will have to be changed soon. I will never buy the 4 pack again. I guess it is true. You get what you pay for, but thought they were the same brush, but they aren't. You can tell by the picture. I will be buying the two pack next time. At this point the 4 pack will last me 4 months, while the 2 pack lasts me 6 months. So it is cheaper to buy the 2 pack. I wouldn't recommend the 4 pack, but would definitely recommend the 2 pack. When I buy the two pack again. I will leave a review to see if it is just the 4 pack or both. Hope this helps. You aren't getting the deal you think by buying the 4 pack. I only buy my replacement heads from Target.
1 reply from Oral-B team - 2 months ago
Thank you for your review, Bill. We’re sorry to hear about your experience with the pack of brush heads you purchased. Please be assured that our products go through many quality checks to ensure they arrive in perfect condition and perform optimally. Your feedback is important to us, and we’ll share it with our Quality Team. We would appreciate the opportunity to learn more about your experience and gather more details for our review. Please call us at (800) 566-7252 so we can assist you further.
4 out of 5 stars
5 September, 2025
originally posted on influenster.com

Great!
[This review was collected as part of a promotion.] My favorite toothbrush. I love these they give such a deep clean without being too aggressive. It really gets my gum line nicely and the small size makes it easy to reach around my wisdom teeth which is usually a hard spot to clean.
5 out of 5 stars
4 September, 2025
originally posted on influenster.com

Nice to brush teeth
[This review was collected as part of a promotion.] I love this product because it is easy to use and it helps rush my teeth better than with my regular toothbrush I love how it spins in order to get everything out and I love how you can get replacement heads so you don’t have to buy the toothbrush in it. It is a little pricey, but it’s worth the price. I receive this product in exchange for my honest review.
1 out of 5 stars
Thumbs down graphic, would not recommend
27 August, 2025Verified purchase
Don't order anything from target!
I would like to review this product but I never got it! I ordered in on August 22, 2025. I was supposed to get it on Sunday, August 24, 2025, but it never arrived. I don’t even have a tracking number now they took my money and now I have no item. Nice going Target.
1 reply from Oral-B team - 3 months ago
Karen, we're sorry to hear that you have not received your order. We recommend contacting Target directly by calling 1-800-440-0680. They'll be able to assist you further and answer any additional questions you may have.
5 out of 5 stars
18 August, 2025
originally posted on influenster.com

Perfect brushes
[This review was collected as part of a promotion.] These are perfect. I love this toothbrush and have been using it for about 2 years. I love these brush heads along with my iQ toothbrush. Clean results, without any discomfort of being too harsh on my gums, and they’re a lot less expensive than other brands’ refills are
5 out of 5 stars
6 August, 2025
originally posted on influenster.com

Gentle for the gums, effective in removing plaque
Dental hygienist here ! I not only use the iO series electric toothbrush but I recommend it to every single one of my patients! I absolutely love that the brush is soft and provides great stimulation for the gums. The only thing I will say, after you’re done brushing, make sure to rinse it well and take it apart from the toothbrush and allow it to dry properly or else it will get crusty.
5 out of 5 stars
28 July, 2025
originally posted on influenster.com

Nice
[This review was collected as part of a promotion.] Durable, super clean, hygienic, easy to change and works great. I love this oral b and all oral b products. It is a great value, very easy to use and open. Packaged nicely. It is very comfortable on my sensitive gums.
5 out of 5 stars
22 July, 2025
originally posted on influenster.com

Easy Oral Hygiene
[This review was collected as part of a promotion.] These are a really good bang for your buck to replace your toothbrush head. Makes keeping on top of your oral hygiene a breeze. I’ll definitely keep using these after they’re used.
5 out of 5 stars
15 July, 2025
originally posted on influenster.com

Love this brush!
[This review was collected as part of a promotion.] I’m so happy to be a part of this program, I already had a brush and got my whole family using these brushes. They work amazingly, they let us know the pressure we’re using, and the time frame. They’re a little pricy but worth the amount. I used to be upset of costs, but after purchasing this I see how worth it, it is. Definitely a must buy, worth the price, worth the results.
4 out of 5 stars
15 July, 2025
originally posted on influenster.com

Oral-B iO Series Ultimate Clean Refills – A Game-C
[This review was collected as part of a promotion.] I’ve been using the Oral-B iO Series with the Ultimate Clean Refills for a few weeks now, and I can honestly say it’s made a noticeable difference in my daily dental hygiene. The combination of powerful yet gentle micro-vibrations and the round, dentist-inspired brush head gives a truly professional clean every time I brush. The bristles feel firm enough to effectively remove plaque but still gentle on my gums, which I appreciate. I especially love how the tufted bristles reach those tricky areas in the back of my mouth that I often struggled with using traditional brush heads. After each use, my teeth feel incredibly smooth and look visibly brighter. I also appreciate the recommendation to change the brush head every three months—it keeps me mindful of maintaining optimal performance and hygiene. Overall, these refills are well worth the investment if you’re looking to elevate your oral care routine. I highly recommend them for anyone who wants that fresh-from-the-dentist clean feeling at home.
5 out of 5 stars
14 July, 2025
originally posted on influenster.com

good!
[This review was collected as part of a promotion.] Oral-B iO Ultimate Clean Refills are well-packaged, have no scent, and provide an excellent deep clean. They’re durable, lasting about 3 months each, and offer great value for the quality.
4 out of 5 stars
11 July, 2025
originally posted on influenster.com

Good
[This review was collected as part of a promotion.] These were good replacements heads for the toothbrush. Easy to put in and lasted and a while. They were not too stiff and adjusted to my mouth well. I would def by these in the future
5 out of 5 stars
10 July, 2025
originally posted on influenster.com

Amazing
[This review was collected as part of a promotion.] Amazing toothbrush head replacements! Very effective in cleaning your teeth and very comfortable on your gums! They last forever and are very affordable!
4 out of 5 stars
8 July, 2025
originally posted on influenster.com

Great
[This review was collected as part of a promotion.] Very sturdy and strong, but still soft and pleasant to use. While it cleans nicely, don’t feel like it wears out quickly. Would recommend for a good brush!