Keep your dentures, retainers and aligners in prime condition with these 120-Count Overnight Denture Tablets from up&up™. These overnight denture tablets easily dissolve in water to remove tough stains and help whiten your dentures while killing up to 99.99% of odor-causing bacteria. A great alternative to brushing, these denture cleaning tablets feature an invigorating mint flavor that refreshes your breath.
up&up™: We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.
Satisfaction guaranteed – Love it or your money back.
Suggested Age: Adult
Product Warning: Keep out of reach of children under 6 years of age
Product Form: Tablet
Package Quantity: 120
TCIN: 92105817
UPC: 191907975819
Item Number (DPCI): 049-09-0126
Origin: Assem USA w/foreign/dom. parts
If the item details aren’t accurate or complete, we want to know about it.
WARNINGS: Do not place tablets or denture cleaning solution in mouth. Do not use to clean natural teeth. See a dentist regularly. Keep this product out of the reach of children. This product contains persulfates, which are a known allergen. In case of accidental ingestion, seek professional assistance or contact the Poison Control Center immediately at 1-800-222-1222.
Shipping details
Estimated ship dimensions: 4.25 inches length x 4 inches width x 6 inches height
Estimated ship weight: 0.87 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
A: Hi - Thank you for reaching out. We appreciate your interest in Overnight Denture and Retainer Tablets. While denture and retainer tablets can be used for cleaning Essix retainers, it's generally recommended to use retainer-specific cleaners for long-term use. Denture cleaners can potentially degrade the plastic of Essix retainers over time due to some of their harsher chemical components. Happy Shopping!! - Emma
submitted byEmma - 1 year ago
Target staff support
Q: What is the minimum time for effective soaking?
These overnight denture tablets are praised for their effectiveness in cleaning dentures and retainers, offering a great value compared to name brands. Guests appreciate their ease of use, simply requiring a soak in water to achieve a deep clean. While some guests experienced issues with discoloration on teeth, many found them to be a reliable and affordable option for maintaining oral hygiene. Overall, they are a popular choice for those seeking a budget-friendly cleaning solution.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.6
4.6 out of 5 stars
133 star ratings
4.6 out of 5 stars with 133 reviews
effectiveness
3.9 out of 5
effectiveness: 3.9 out of 5
quality
3.9 out of 5
quality: 3.9 out of 5
value
4.0 out of 5
value: 4 out of 5
76% would recommend
21 recommendations
5 out of 5 stars
11 August, 2026Verified purchase
(no review title)
We use these to sanitize retainers, works great
Kaw7694
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5 out of 5 stars
11 May, 2026Verified purchase
(no review title)
Great for soaking retainers!
Summer1727
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5 out of 5 stars
Thumbs up graphic, would recommendWould recommend
1 May, 2026Verified purchase
(no review title)
Great value.
Kee Lee
effectiveness
5.0 out of 5
effectiveness: 5 out of 5
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5.0 out of 5
quality: 5 out of 5
value
5.0 out of 5
value: 5 out of 5
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1 out of 5 stars
Thumbs down graphic, would not recommendWould not recommend
14 April, 2026Verified purchase
Maybe for Dentures
Maybe good for teeth. I read magazine you could use for cleaning toilets
Dog lover
effectiveness
1.0 out of 5
effectiveness: 1 out of 5
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1.0 out of 5
quality: 1 out of 5
value
1.0 out of 5
value: 1 out of 5
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5 out of 5 stars
Thumbs up graphic, would recommendWould recommend
29 March, 2026Verified purchase
wonderful deal
great product & great price
Robert
effectiveness
5.0 out of 5
effectiveness: 5 out of 5
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5.0 out of 5
quality: 5 out of 5
value
5.0 out of 5
value: 5 out of 5
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5 out of 5 stars
Thumbs up graphic, would recommendWould recommend
16 March, 2026Verified purchase
Works as well as polident
I was surprised but also very happy that it is cheaper! Used polident for years because it worked so well and like everything else the price is getting too pricey ….so I tried The target up & up brand. YAY ME I GOT A WIN lol. It’s worth your time to try the overnight tablet. The price won’t put you back either.
Mr and Mrs
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5.0 out of 5
effectiveness: 5 out of 5
quality
5.0 out of 5
quality: 5 out of 5
value
5.0 out of 5
value: 5 out of 5
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5 out of 5 stars
Thumbs up graphic, would recommendWould recommend
10 March, 2026Verified purchase
Great cleaner for retainers
I've used these tablets over a year now to clean my retainer. Works great, would definitely recommend.
LG
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5.0 out of 5
effectiveness: 5 out of 5
quality
5.0 out of 5
quality: 5 out of 5
value
5.0 out of 5
value: 5 out of 5
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1 out of 5 stars
Thumbs down graphic, would not recommendWould not recommend
1 March, 2026Verified purchase
⚠️ Be careful using this for retainers — caused discoloration on my teeth
I bought these tablets to clean my orthodontic retainer and used them twice a week, soaking the retainer during the day and rinsing it before wearing it at night. After a few weeks, I noticed yellowish spots developing on my front teeth that I had never had before. I later realized this product is formulated for dentures, not retainers that sit tightly against natural teeth. My dentist advised me to stop using it immediately. The spots are still there and I may need treatment to correct them. I’m sharing this so others don’t make the same mistake.
K
effectiveness
1.0 out of 5
effectiveness: 1 out of 5
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quality: 1 out of 5
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1.0 out of 5
value: 1 out of 5
12 guests found this review helpful. Did you?
3 out of 5 stars
Thumbs down graphic, would not recommendWould not recommend
3 January, 2026Verified purchase
(no review title)
it says that it can get rid of stains and stuff that normal brushing can't, but that doesn't seem to be true. I've only tried it once but it doesn't really seem to visibly clean at all.
Aspen
effectiveness
2.0 out of 5
effectiveness: 2 out of 5
quality
3.0 out of 5
quality: 3 out of 5
value
3.0 out of 5
value: 3 out of 5
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1 out of 5 stars
Thumbs down graphic, would not recommendWould not recommend
19 December, 2025
(no review title)
Absolutely disappointed in the fact that there was no delivery and really poor communication in getting this handled I am really reconsidering my membership
Roberta
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5 out of 5 stars
Thumbs up graphic, would recommendWould recommend
16 December, 2025Verified purchase
(no review title)
Superb
Besilda
effectiveness
5.0 out of 5
effectiveness: 5 out of 5
quality
5.0 out of 5
quality: 5 out of 5
value
5.0 out of 5
value: 5 out of 5
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4 out of 5 stars
Thumbs up graphic, would recommendWould recommend
3 August, 2025Verified purchase
Not bad, for an inexpensive product
A warning, these tabs do give off a bit of a chlorine-smelling fume when placed in water, so give yourself some distance after you plop your dental implement in the solution. However, it does the job, does not leave a residue, and you can't beat it for the cost. A thumbs up, Target.
JenL
effectiveness
5.0 out of 5
effectiveness: 5 out of 5
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4.0 out of 5
quality: 4 out of 5
value
5.0 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommendWould recommend
12 July, 2025Verified purchase
Great
I use these for my Invisalign and it works amazing
These Up&Up Overnight Denture Tablets clean dentures effectively and leave them fresh without residue. Affordable and just as good as name brands! Bonus—they’re great for dropping in the toilet to remove stains. Highly recommend!
These overnight denture tablets work great! They clean thoroughly, removing stains and buildup while leaving my dentures feeling fresh in the morning. Just drop a tablet in water, let it soak overnight, and rinse—super simple. There’s no harsh smell or aftertaste, just a deep clean. Definitely a must-have for keeping dentures looking and feeling their best!
I don’t personally use these however the packaging of these denture tablets was phenomenal. Perforated edges in the packets of tablets was easy to rip off. Looked like it was easy to dissolve in water for the dentures to be cleaned.
I use these to clean my retainer during the day, and they do the trick. The box has plenty of tablets and it’s a great value. They work as good as name brand for a much cheaper price. Highly recommend.
Ian H
5 guests found this review helpful. Did you?
2 out of 5 stars
Thumbs down graphic, would not recommendWould not recommend
I dont really care for these tablets. They dont work as well as other products i have tried. You have to use two or three of them just to get a good effect. They are good in a pinch but not something i would buy.
My husband loved using this overnight cleaner on his temporary dentures, saying that they cleaned really well overnight, and didnt have a weird aftertaste. The fiz from the bubbles really seemed to do their job, and cleaned really well. Plus it has a nice fresh scent to it, too.
