Textbook of Von Willebrand Disease - 2nd Edition by Augusto B Federici & Erik E Berntorp & David Lillicrap & Robert R Montgomery (Hardcover)

About the Book

"Von Willebrand Disease: Basic and Clinical Aspects Second Edition describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding, GI bleeding, and how to prepare VWB patient for surgery. Many advances in agents are included in this updated edition as well as the wide topics such as VWF beyond Hemostasis, in Angiogenesis, and VWF/ADAMTS13 as risk factors of thrombosis. This valuable book is written by an international team of editors and contributors and is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis"--

Book Synopsis

Comprehensive resource summarizing recent research on von Willebrand disease, showing clinicians how to optimize management of patients with this disorder

The newly revised and updated second edition of Textbook of von Willebrand Disease: Basic and Clinical Aspects, 2^nd edition describes the important and complex role of von Willebrand factor (VWF) in hemostasis and thrombosis, covering not only the current understanding of its molecular biology, but also the association between genetic variants of VWF and different von Willebrand disease (VWD) phenotypes. The text also reviews the important area of the obstetric and gynecological manifestations of VWD, as well as how to manage patients with VWD for surgery.

Many advances in agents are included in this updated edition, as well as the wide topics such as VWF in Angiogenesis, and VWF/ADAMTS13 as risk factors of thrombosis.

Edited by a team of experts in VWD and an international team of contributors, Textbook of von Willebrand Disease covers sample topics such as:

• VWF structure and function, biosynthesis and organization of VWF, modulation of VWF by ADAMTS13 and assessment of VWF clearance
• Clinical, laboratory and molecular markers of different VWD types, from the mild forms of type 1 VWD and the moderate variants types 2A, 2B, 2M, 2N to the most severe type 3 VWD
• Pediatric aspects of VWD and of women with VWD
• Management of GI bleeds and appropriate therapies in surgery, and plasma-derived and recombinant VWF concentrates
• Acquired von Willebrand Syndrome, cardiovascular causes of AVWS, gastrointestinal bleeds in VWD and AVWS, and prophylaxis in von Willebrand disease

Providing complete and accessible coverage of the subject, Textbook of von Willebrand Disease: Basic and Clinical Aspects, 2^nd edition is a valuable resource for hematologists in practice and in training, along with specialists in thrombosis, hemostasis, and bleeding/clotting disorders.

From the Back Cover

Comprehensive resource summarizing recent research on von Willebrand disease, showing clinicians how to optimize management of patients with this disorder

The newly revised and updated second edition of Textbook of von Willebrand Disease: Basic and Clinical Aspects, 2^nd edition describes the important and complex role of von Willebrand factor (VWF) in hemostasis and thrombosis, covering not only the current understanding of its molecular biology, but also the association between genetic variants of VWF and different von Willebrand disease (VWD) phenotypes. The text also reviews the important area of the obstetric and gynecological manifestations of VWD, as well as how to manage patients with VWD for surgery.

Many advances in agents are included in this updated edition, as well as the wide topics such as VWF in Angiogenesis, and VWF/ADAMTS13 as risk factors of thrombosis.

Edited by a team of experts in VWD and an international team of contributors, Textbook of von Willebrand Disease covers sample topics such as:

• VWF structure and function, biosynthesis and organization of VWF, modulation of VWF by ADAMTS13 and assessment of VWF clearance
• Clinical, laboratory and molecular markers of different VWD types, from the mild forms of type 1 VWD and the moderate variants types 2A, 2B, 2M, 2N to the most severe type 3 VWD
• Pediatric aspects of VWD and of women with VWD
• Management of GI bleeds and appropriate therapies in surgery, and plasma-derived and recombinant VWF concentrates
• Acquired von Willebrand Syndrome, cardiovascular causes of AVWS, gastrointestinal bleeds in VWD and AVWS, and prophylaxis in von Willebrand disease

Providing complete and accessible coverage of the subject, Textbook of von Willebrand Disease: Basic and Clinical Aspects, 2^nd edition is a valuable resource for hematologists in practice and in training, along with specialists in thrombosis, hemostasis, and bleeding/clotting disorders.

About the Author

Professor Augusto B. Federici, Hematology and Transfusion Medicine, L. Sacco University Hospital and University of Milan, Milan, Italy.

Professor Erik E. Berntorp, Department of Translational Medicine, Malmö Centre for Thrombosis and Haemostasis, Lund University, Skåne University Hospital, Malmö, Sweden.

Professor David Lillicrap, Department of Pathology and Molecular Medicine, Richardson Laboratory, Queen's University, Kingston, ON, Canada.

Professor Robert R. Montgomery, Pediatrics (Hematology) and Vice Chair, Versiti Blood Research Institute, Medical College of Wisconsin, Milwaukee, WI, USA.