Page counts vary by edition; most listings show either 368 pages or 384 pages.

Defy Me is presented as young adult dystopian fiction and is listed with a suggested age of 14 years.

Dimensions vary by edition: height about 7.8–8.3 inches, width 5.3–5.8 inches, depth 1.0–1.4 inches; weight ranges from 0.6 to 0.95 pounds.

It is presented as the fifth book in the series.

The deluxe limited paperback is described as a collector's edition with a shimmery cover and shiny gloss, silver holographic edges, a vivid new colorway, and is noted as limited in quantity.

The protagonist discovers she isn't who she thought, begins to unravel a lifetime of lies, and must choose whether to become a weapon or a warrior while fighting to protect the people she loves and confronting a war within her mind.