Autophagy: Mechanisms and Pathophysiological Implications - by Alexandra Hewitt (Hardcover)

About the Book

Autophagy is a vital cellular process where cells degrade and recycle their own components. It plays a crucial role in maintaining cellular health and adapting to stress conditions. Through autophagy, damaged organelles, misfolded proteins, and other dysfunctional cellular components are engulfed by double-membrane vesicles called autophagosomes. These vesicles then fuse with lysosomes, where their contents are broken down by lysosomal enzymes and recycled into new biomolecules for cellular repair and energy production. Research indicates that autophagy is involved in various physiological processes, including development, immunity, and aging. Dysregulation of autophagy is linked to several diseases, such as cancer, neurodegenerative disorders, and metabolic conditions. Understanding the mechanisms of autophagy has opened new avenues for therapeutic interventions aimed at modulating this process to treat or prevent diseases associated with its dysfunction. This book strives to provide a fair idea about this discipline and helps develop a better understanding of the latest advances within this field. The various researches on immunology along with technological progress that have future implications are glanced at in this book. With its detailed analyses and data, this book will prove immensely beneficial to professionals and students involved in this area at various levels.

Book Synopsis

Autophagy is a vital cellular process where cells degrade and recycle their own components. It plays a crucial role in maintaining cellular health and adapting to stress conditions. Through autophagy, damaged organelles, misfolded proteins, and other dysfunctional cellular components are engulfed by double-membrane vesicles called autophagosomes. These vesicles then fuse with lysosomes, where their contents are broken down by lysosomal enzymes and recycled into new biomolecules for cellular repair and energy production. Research indicates that autophagy is involved in various physiological processes, including development, immunity, and aging. Dysregulation of autophagy is linked to several diseases, such as cancer, neurodegenerative disorders, and metabolic conditions. Understanding the mechanisms of autophagy has opened new avenues for therapeutic interventions aimed at modulating this process to treat or prevent diseases associated with its dysfunction. This book strives to provide a fair idea about this discipline and helps develop a better understanding of the latest advances within this field. The various researches on immunology along with technological progress that have future implications are glanced at in this book. With its detailed analyses and data, this book will prove immensely beneficial to professionals and students involved in this area at various levels.