Bioinformatics - 4th Edition by Andreas D Baxevanis & Gary D Bader & David S Wishart (Hardcover)

About the Book

"This fully revised Fourth Edition to a best-selling resource provides the reader with a hands-on guide to computational biology, primarily in the area of sequence analysis. The subject matter will cover a broad spectrum of concepts in bioinformatics, beginning with an overview of biological databases and ending with a series of chapters on predictive and comparative algorithms. Using relevant biological examples, the book will provide background on and strategies for using many of the most powerful and commonly-used algorithms for sequence-based discovery. Given the explosion in the number of organisms whose genomes have been sequenced over the last several years, the emergence of new types of data sets (particularly those derived using next-generation sequencing technologies), and increasing emphasis on being able to make effective use of "big data", the book is both timely and important to investigators in molecular biology and related fields. With a full-color, enlarged page design, this edition offers the most readable, up-to-date, and thorough introduction to the field for biologists. The new "Foundations" section insures that readers have a firm understanding of the technologies that generate the data, as well as the essential statistical and programming tools. Features include special boxes, enhanced use of real examples, and problem sets with answers provided on the book's dedicated website (www.wiley.com/bioinformatics). A glossary and appendix of sample file formats rounds out the book's reader-friendly, 'hands-on' treatment"--

Book Synopsis

Praise for the third edition of Bioinformatics

"This book is a gem to read and use in practice."
--Briefings in Bioinformatics

"This volume has a distinctive, special value as it offers an unrivalled level of details and unique expert insights from the leading computational biologists, including the very creators of popular bioinformatics tools."
--ChemBioChem

"A valuable survey of this fascinating field. . . I found it to be the most useful book on bioinformatics that I have seen and recommend it very highly."
--American Society for Microbiology News

"This should be on the bookshelf of every molecular biologist."
--The Quarterly Review of Biolog

The field of bioinformatics is advancing at a remarkable rate. With the development of new analytical techniques that make use of the latest advances in machine learning and data science, today's biologists are gaining fantastic new insights into the natural world's most complex systems. These rapidly progressing innovations can, however, be difficult to keep pace with.

The expanded fourth edition of the best-selling Bioinformatics aims to remedy this by providing students and professionals alike with a comprehensive survey of the current field. Revised to reflect recent advances in computational biology, it offers practical instruction on the gathering, analysis, and interpretation of data, as well as explanations of the most powerful algorithms presently used for biological discovery. Bioinformatics, Fourth Edition offers the most readable, up-to-date, and thorough introduction to the field for biologists at all levels, covering both key concepts that have stood the test of time and the new and important developments driving this fast-moving discipline forwards.

This new edition features:

• New chapters on metabolomics, population genetics, metagenomics and microbial community analysis, and translational bioinformatics
• A thorough treatment of statistical methods as applied to biological data
• Special topic boxes and appendices highlighting experimental strategies and advanced concepts
• Annotated reference lists, comprehensive lists of relevant web resources, and an extensive glossary of commonly used terms in bioinformatics, genomics, and proteomics

Bioinformatics is an indispensable companion for researchers, instructors, and students of all levels in molecular biology and computational biology, as well as investigators involved in genomics, clinical research, proteomics, and related fields.

From the Back Cover

A CUTTING-EDGE GUIDE TO BIOINFORMATICS AND ITS ROLE IN MODERN BIOLOGY

The field of bioinformatics is advancing at a remarkable rate. With the development of new analytical techniques that make use of the latest advances in machine learning and data science, today's biologists are gaining fantastic new insights into the natural world's most complex systems. These rapidly progressing innovations can, however, be difficult to keep pace with.

The expanded fourth edition of the best-selling Bioinformatics aims to remedy this by providing students and professionals alike with a comprehensive survey of the current field. Revised to reflect recent advances in computational biology, it offers practical instruction on the gathering, analysis, and interpretation of data, as well as explanations of the most powerful algorithms presently used for biological discovery. Bioinformatics, Fourth Edition offers the most readable, up- to-date, and thorough introduction to the field for biologists at all levels, covering both key concepts that have stood the test of time and the new and important developments driving this fast-moving discipline forward.

This new edition features:

• New chapters on metabolomics, population genetics, metagenomics and microbial community analysis, and translational bioinformatics
• A thorough treatment of statistical methods as applied to biological data
• Special topic boxes and appendices highlighting experimental strategies and advanced concepts
• Annotated reference lists, comprehensive lists of relevant web resources, and an extensive glossary of commonly used terms in bioinformatics, genomics, and proteomics

Bioinformatics is an indispensable companion for researchers, instructors, and students of all levels in molecular biology and computational biology, as well as investigators involved in genomics, clinical research, proteomics, and related fields.

Praise for the Third Edition of BIOINFORMATICS

"This book is a gem to read and use in practice."
--Briefings in Bioinformatics

"This volume has a distinctive, special value as it offers an unrivalled level of details and unique expert insights from the leading computational biologists, including the very creators of popular bioinformatics tools."
--ChemBioChem

"A valuable survey of this fascinating field. . . I found it to be the most useful book on bioinformatics that I have seen and recommend it very highly."
--American Society for Microbiology News

"This should be on the bookshelf of every molecular biologist."
--The Quarterly Review of Biology

About the Author

EDITED BY

ANDREAS D. BAXEVANIS, PhD, Director of Computational Biology for the National Institutes of Health's Intramural Research Program and a Senior Scientist leading the Computational Genomics Unit at the NIH's National Human Genome Research Institute, Bethesda, MD, USA.

GARY D. BADER, PhD, Ontario Research Chair in Biomarkers of Disease and Professor at the Donnelly Centre and the Departments of Molecular Genetics and Computer Science at the University of Toronto, Toronto, ON, Canada.

DAVID S. WISHART, PhD, Distinguished University Professor in the Departments of Biological Sciences and Computing Science at the University of Alberta, Edmonton, AB, Canada.