New ArrivalsHoliday Hosting & EntertainingChristmasGift IdeasClothing, Shoes & AccessoriesHomeFurnitureToysElectronicsBeautyGift CardsCharacter ShopBabyKitchen & DiningGroceryHousehold EssentialsSchool & Office SuppliesVideo GamesMovies, Music & BooksParty SuppliesBackpacks & LuggageSports & OutdoorsPersonal CareHealthPetsUlta Beauty at TargetTarget OpticalBullseye’s PlaygroundDealsClearanceTarget New Arrivals Target Finds #TargetStyleDía de MuertosHanukkahStore EventsAsian-Owned Brands at TargetBlack Beyond MeasureMás QueWomen-Owned Brands at TargetLGBTQIA+ ShopTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Gentle Premium Powder Infant Formula - 34oz - up&up™ - 2 of 4Gentle Premium Powder Infant Formula - 34oz - up&up™ - 3 of 4Gentle Premium Powder Infant Formula - 34oz - up&up™ - 4 of 4
Gentle Premium Powder Infant Formula - 34oz - up&up™ - 1 of 4

Gentle Premium Powder Infant Formula - 34oz - up&up™

$28.39 ($0.84/ounce) reg $35.49
Sale 
save $7.10 (20% off)

In Stock

Eligible for registries and wish lists

At a glance

Sponsored

About this item

Highlights

  • Compare to the nutrition of Enfamil NeuroPro Gentlease
  • Easy to digest, for fussiness, gas and crying
  • Complete nutrition to support growth, brain and general development
  • Gentle Immune Blend 6 including 2'-FL HMO for immune support
  • NON-GMO, no artificial colors, flavors or growth hormones

Description

Compare to the nutrition of Enfamil Neuropro Gentlease. up&up™ Gentle Premium Infant Formula offers complete nutrition to support your baby's growth, brain and general development. For fussiness, gas and crying, this soothing formula contains Gentle Immune Blend 6 with 2’-FL HMO, Vitamin C and E, Selenium, Partially Hydrolyzed Whey Protein, Reduced Lactose (has 20 percent the lactose compared to our full lactose, routine, milk-based Infant Premium formula). Human Milk Oligosaccharide not from human milk. NON-GMO, ingredients not genetically engineered. No artificial growth hormones; no significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows. Certified Kosher by the Orthodox Union - OU-D. This product is not manufactured or distributed by the owner of trademark Enfamil Neuropro and registered trademark Gentlease.

100% Satisfaction Guaranteed.

Serving Size: 5 fl oz

Amount :

Calories: 100
% Daily Value*
Protein 2.3g
Biotin 3mcg
Total Fat 5.3g
Vitamin C 12mg
Total Carbohydrate 10.8g
Choline 24mg
Water 134g
Inositol 24mg
Omega-6 (linoleic acid LA) 780mg
Calcium 82mg
Vitamin A 300iu
Phosphorus 46mg
Vitamin D 60iu
Magnesium 8mg
Vitamin E 2iu
Iron 1.8mg
Vitamin K 1mcg
Zinc 1mg
Thiamin 15mcg
Manganese 140mcg
Copper 75mcg
Riboflavin 60mcg
Iodine 15mcg
Vitamin B6 0.3mcg
Selenium 2.8mcg
Vitamin B12 1000mcg
Sodium 40mg
Niacin 16mcg
Potassium 108mg
Folic Acid 500mcg
Pantothenic Acid 63mg
Chloride 63mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

corn syrup, nonfat milk, palm olein, partially hydrolyzed whey, soy oil, coconut oil, high oleic (safflower or sunflower) oil, less than 2%: 2'-fucosyllactose (2'-fl), mortierella alpina oil**, schizochytrium sp. oil** l-carnitine, mixed tocopherol concentrate, monoglycerides, soy lecithin, taurine, calcium carbonate, calcium chloride, cupric sulfate, ferrous sulfate, magnesium chloride, manganese sulfate, potassium bicarbonate, potassium hydroxide, potassium iodide, potassium phosphate, sodium citrate, sodium selenite, zinc sulfate, ascorbic acid, ascorbyl palmitate, beta-carotene, biotin, calcium pantothenate, choline bitartrate, cyanocobalamin, folic acid, inositol, niacinamide, pyridoxine hydrochloride, riboflavin, thiamin hydrochloride, vitamin a palmitate, vitamin d (cholecalciferol), vitamin e (di-alpha tocopheryl acetate), vitamin k (phytonadione).' '

Allergens & Warnings:

WARNING: DO NOT USE MICROWAVE TO PREPARE OR WARM FORMULA. SERIOUS BURNS MAY OCCUR., CONTAINS MILK AND SOY.
Baby Formula Focus: Easy to Digest
Base Ingredient: Hydrolyzed Protein
Dietary Needs: Gluten-Free, Kosher
Form: Powdered
State of Readiness: Mix
Package Quantity: 1
Age Stage: Infant
Net weight: 24 Ounces
TCIN: 87765855
UPC: 085239987643
Item Number (DPCI): 007-09-0005
Origin: Made in the USA or Imported
Grocery Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers. Any additional pictures are suggested servings only.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 5.1 inches length x 5.1 inches width x 7.3 inches height
Estimated ship weight: 2.381 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.

Q: Is using warm water a requirement to prepare it, or can I prepare with room temperature water?

submitted by Marina - 11 days ago
  • A: Hello, thank you for your question. For mixing formula, the water should be warm approximately 100F (40C). This is our recommendation as it is closest to the child’s body temperature and this will also help in the reconstitution of the formula.

    submitted bythe Supplier - 5 days ago
    Brand expert

Q: Is this the same as it used to be three years ago and just difference packaging than before?

submitted by Lisa0910 - 5 months ago
  • A: Hello, thank you for your question. We are still the manufacturing of the Up & Up infant formula. This is still the Gentle formula and is compared to the nutrition of Enfamil Neuropro Gentlease. Over the years there may have been some changes to the formulation to stay comparable to Enfamil and continue to support our little ones the best we can.

    submitted bythe Supplier - 5 months ago
    Brand expert

Infant Formula Baby Collection - up&up™

Infant Formula Baby Collection - up&up™

Infant Formula Collection - up&up™

Infant Formula Collection - up&up™

Related Categories

Guests are saying

This formula has garnered mixed feedback from guests, with many praising its affordability and effectiveness for babies transitioning from name brands. While some guests report positive experiences with reduced gas and constipation, others have encountered issues such as constipation and vomiting. The formula's similarity to name brands like Enfamil is highlighted, making it a viable option for budget-conscious parents. Overall, it offers a cost-effective alternative worth considering for various feeding needs.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.3 out of 5 stars with 422 reviews
    easy on tummy: 3.64 out of 5
    easy to prepare: 4.55 out of 5
    quality: 3.8 out of 5
    value: 4.06 out of 5
    62% would recommend
    110 recommendations
    5 out of 5 stars
    Thumbs up graphic, would recommend
    31 October, 2025Verified purchase

    (no review title)

    The price of this versus name brand is an insane deal. My baby has never had an issue with this formula and we love it!
    Paige
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    24 October, 2025Verified purchase

    (no review title)

    Babies love this formula!
    gwsnaps
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    5 October, 2025Verified purchase

    Constipation

    I tried this formula for 3 weeks with my child as a wallet-friendly alternative to Enfamil Gentlease. Unfortunately my infant very quickly became constipated and having stomach pains, so I had to switch back.
    Gaby
    easy on tummy: 1 out of 5
    easy to prepare: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    3 October, 2025Verified purchase

    My baby loves this brand!!

    My little baby loves this stuff!! I had to start buying this when I was having a hard time with money and had to save. We originally had her on enfamil and I tried to switch back to enfamil and she would not have it!! Nope. So back to Target brand I went. She was a happy camper and it was so easy on her little tummy!!
    Misty
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    26 September, 2025Verified purchase

    Best Option for GERD babies

    It mixes well, and my baby girl tolerates it much better than the name-brand version! There is little to no spit-up, and she has GERD. Very satisfied.
    Deia
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    18 September, 2025Verified purchase

    Gentle for Newborns

    This gentle baby formula works wonderfully for sensitive tummies. It eased my son’s acid reflux and gave him comfort, making feeding time so much easier. It really helped him. He has been using it for 6 months (since a newborn). It does not clump when mixing with a machine or hand mixing.
    Lizzie
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    7 September, 2025Verified purchase

    PLEASE do not give this to your baby

    We have been giving this to our son for several days and each time he had a bottle he spit up more and more until eventually we started noticing other things like a cough, slight wheezing, and being very constipated. Today is where it all made sense. He pooped this morning finally, if you can even call it that, I won’t describe here but it was the craziest thing I’ve ever seen — nothing normal about it. This afternoon is when it was clear he was having an allergic reaction… he vomited profusely and then became lethargic. It was so so scary and we almost took him to the hospital. I then started to research (which I should have done before trying this but I trusted Target, not anymore). The first ingredient is corn syrup… why?! This should not be in formula at all, and certainly not the first ingredient. Aside from the crazy amount of sugar, I have a corn allergy and while I’m not sure if this could affect him if he has one, I’d rather play it safe and avoid it. We used By Heart before trying this as a cheaper option, but you get what you pay for I guess. Switching back now. Please do an ingredient comparison before you try this for your sweet baby, they don’t deserve these ingredients.
    1 reply from the Product Manufacturer team - 2 months ago
    We are sorry to hear that this was your little one's experience with the Up & Up Gentle Formula. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2080809. We look forward to addressing your concerns and hearing from you!
    Miriam
    easy on tummy: 1 out of 5
    easy to prepare: 3 out of 5
    quality: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    3 September, 2025Verified purchase

    Love it

    I have tried all of the types of “gentlease” and this is bug far my favorite when it comes to price and the way my baby feels. This is the only formula he doesn’t spit up or cry after finishing!
    Nicole
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    1 September, 2025Verified purchase

    Great buy!

    My baby loves this formula. We tried the name brand enfamil gentlease and she was soooo fussy. I tried the name brand enfamil neuropro and this one and either one works. This one we purchase more because of the pricing !!!
    Lindsey
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    1 out of 5 stars
    30 August, 2025Verified purchase

    Made baby sick after every bottle

    If your baby does well on Enfamil Gentle Ease don’t buy this! I gave this formula a chance because of the price compared to Enfamil, but it made my son throw up after every bottle! We switched him back to Enfamil and he stopped getting sick immediately! I never post review but wanted to warn other parents to avoid this formula!
    Paige
    1 guest found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    24 August, 2025Verified purchase

    You get what you pay for

    I like the cost, but it's not worth it. My son was constipated, bloated and extremely fussy. Nothing could calm him down, so he cried himself to sleep. Again, not worth the pain and suffering. I will buy the name brand.
    1 reply from the Product Manufacturer team - 2 months ago
    We are sorry to hear about your experience with the Up & Up Gentle Formula. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2076525. We look forward to addressing your concerns and hearing from you!
    Corey
    easy on tummy: 1 out of 5
    easy to prepare: 4 out of 5
    quality: 1 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    23 August, 2025Verified purchase

    Great for our newborn

    Seems to be equal to, if not better, than Gentlease. Love the price!
    mackenzieg
    easy on tummy: 4 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    22 August, 2025Verified purchase

    Best formula

    I started getting this formula for my baby and no problems at all other formulas made her tummy hurt
    Jessy
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    16 August, 2025
    originally posted on influenster.com
    Image

    Great product

    [This review was collected as part of a promotion.] Mixed well, not clumpy. Packaging was slick and easy to open. Great ingredients for digestion. My son seem to like the taste and tolerate the formula well.
    suzanneccbdb_6503
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    15 July, 2025Verified purchase

    Only formula we use

    Love this formula for our baby. It's the only one we use. Very comparable to name brands but you get a lot more for a lot less!
    sarahl
    easy on tummy: 4 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    4 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    14 July, 2025Verified purchase

    10/10

    Perfect dupe for enfamil gentlease and so much cheaper!
    Melyssa
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    3 guests found this review helpful. Did you?
    5 out of 5 stars
    11 July, 2025Verified purchase

    Milk

    I like this brand my baby uses gentle ease through wic and once I run out for the month I like to look for a big can I tried this one and it’s very good it made my son poops come out very soft and easy with the branded one I always see his poops like little balls like he had a hard time pooping I love this formula this formula made his poop softer and he loves the milk
    S
    1 guest found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    24 June, 2025

    Fussy and Constipated Newborn

    Don’t be fooled by this — it is NOT like it’s name brand competitor. I am currently supplementing with formula while breastfeeding, and this formula made my baby extremely constipated and fussy. It gave him horrible gas and he was so fussy he fought sleep and naps. He was finally able to poop after just one bottle of the name brand competitor’s formula.
    1 reply from the Product Manufacturer team - 4 months ago
    We are sorry to hear that the Gentle formula was not a good fit for your little one. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We encourage you to reach out to our contact center at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2057496. We look forward to addressing your concerns and hearing from you!
    megmomof2
    easy on tummy: 1 out of 5
    easy to prepare: 3 out of 5
    quality: 1 out of 5
    value: 1 out of 5
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    24 June, 2025Verified purchase

    Similar to the expensive brand

    Very similar to the more expensive brand. Similar ingredients and was very easy to switch to and it’s much cheaper highly recommended
    Pb
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    18 June, 2025Verified purchase

    Save money, buy the Up&Up

    Actually, it's better than the name brand IMO. Mixes better, and baby loved it. Absolutely no issues with this formula.
    Boy Mama
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    2 guests found this review helpful. Did you?

    Get top deals, latest trends, and more.

    Privacy policy

    Footer

    About Us

    About TargetCareersNews & BlogTarget BrandsBullseye ShopSustainability & GovernancePress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

    Help

    Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member ServicesLegal & Privacy

    Stores

    Find a StoreClinicPharmacyTarget OpticalMore In-Store Services

    Services

    Target Circle™Target Circle™ CardTarget Circle 360™Target AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
    PinterestFacebookInstagramXYoutubeTiktokTermsCA Supply ChainPrivacy PolicyCA Privacy RightsYour Privacy ChoicesInterest Based AdsHealth Privacy Policy