Immune Support Probiotic Dietary Supplement Capsules - 30ct - up&up™
$14.69 ($0.49/count)
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Highly rated
$17.89 - $28.49
Buy 1, get 1 30% off Culturelle items
4.6 out of 5 stars with 1971 ratings
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4.6 out of 5 stars with 156 reviews
quality: 4.47 out of 5
value: 4.11 out of 5
80% would recommend
25 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
9 August, 2025Verified purchase
Gut super power
This is the only strain that is safe for me to take. It works great for me and got my gut issues back in order! Target please keep selling these! I highly recommend!
5 out of 5 stars
Thumbs up graphic, would recommend
9 July, 2025
Unlike Culturelle, these dont have inulin!
Please don’t stop making these!
5 out of 5 stars
Thumbs up graphic, would recommend
6 July, 2025Verified purchase
Excellent Product
I really like Target Up and Up products. This probiotic works great at a great price!
5 out of 5 stars
Thumbs up graphic, would recommend
20 June, 2025Verified purchase
Works better than I expected.
I got these while on antibiotics instead of the name brand ones I used to use. I wanted to save a few bucks and they seemed to do the job as needed. They did not bother my stomach like some others tend to do when first starting and they seemed to help prevent issues that antibiotics can cause.
3 out of 5 stars
12 May, 2025
Price went up 30%!?!
Really liked the product and the reasonable price, but now you’ve marked it up 30%!?! Why such a large increase!?!
5 out of 5 stars
Thumbs up graphic, would recommend
13 November, 2024Verified purchase
Effective
I’m generally skeptical about supplements, but these probiotics started working within hours and I feel much better. If your gut biome has been wiped out, give these a try.
1 out of 5 stars
Thumbs down graphic, would not recommend
15 April, 2024Verified purchase
Awful
I take probiotics as part of my daily routine and have never experienced gas pains and constipation with any before taking these. My husband and I have both been having digestive problems since we started. He’s got nausea, painful gas and bloating and I have painful gas, bloating, and constipation. And that’s just after a few days! Don’t recommend. Spend the extra money and get a different brand.
5 out of 5 stars
Thumbs up graphic, would recommend
19 November, 2023Verified purchase
Review
Great product great value
1 out of 5 stars
Thumbs down graphic, would not recommend
8 June, 2023Verified purchase
Nonstop puking
I couldn’t stop throwing up after taking this. Absolutely awful.
5 out of 5 stars
Thumbs up graphic, would recommend
30 May, 2023Verified purchase
Great
This is my 2nd box of this product and I defnitely see the benefits.
5 out of 5 stars
Thumbs up graphic, would recommend
25 March, 2023Verified purchase
Solved post-flu GI issues!
Similar to a previous reviews, I tried this out of desperation after catching a terrible couple flus in a row. My GI tract had been messed up for about 5 weeks with PI-IBS like symptoms. Within a few days, my system had calmed down, and my symptoms ceased. I've been on it a couple weeks now and feel "normal" again. This was also one of the only probiotics in the store under 40 bil. that didn't have bovine gelatin or skim milk in the ingredients. I've been following an online suggestion of taking the probiotic with breakfast and haven't experienced any gastro upset from it.
5 out of 5 stars
Thumbs up graphic, would recommend
22 February, 2023Verified purchase
Daily routine
Great product I take it every morning. Each time I order these pills they come in excellent condition. Easy to swallow.
2 out of 5 stars
Thumbs down graphic, would not recommend
27 January, 2023Verified purchase
New packaging with marked price increase
Same product that had been on the shelf for years, but now with a 30% markup.
5 out of 5 stars
Thumbs up graphic, would recommend
9 January, 2023Verified purchase
My favorite one
Favorite I’ve tried so far, better than name brands and price is great
3 out of 5 stars
Thumbs down graphic, would not recommend
21 December, 2022Verified purchase
If you enjoy diarrhea...
The count is way too high and I wish I had done more research before buying. No one has time for the poops.
5 out of 5 stars
Thumbs up graphic, would recommend
10 December, 2022
Yes!
This probiotic literally saved me for c.diff. I had been on an antibiotic for a sinus infection, and something went terribly wrong and I was infected with cdiff. Taking this along with activia yogurt in the morning really helped fight it off and regulate my gut again!
5 out of 5 stars
Thumbs up graphic, would recommend
2 October, 2022Verified purchase
Feeling better
I lost weight and am not tired! I bought this product because I had been on an antibiotics back to back for an ear infection. I had no idea the full scope of benefits probiotics provide! I noticed I was using the bathroom more and thought, that's weird and then thought well the only thing I'm doing differently is the probiotics. Then when I went back to the doctor I lost weight and I was only there a few weeks before and then I decided to Google probiotics and what they do. So I can safely say this one works well and I'm pleased with the results. I would have taken it sooner if I had known!
5 out of 5 stars
Thumbs up graphic, would recommend
1 June, 2022Verified purchase
LOVE THIS
Love this! I’ve been pretty irregular since I began my iud journey and this regulated my system back to normal.
5 out of 5 stars
Thumbs up graphic, would recommend
6 May, 2022Verified purchase
Probactic
I Take These Because They're Easy To Take
4 out of 5 stars
Thumbs up graphic, would recommend
10 January, 2022Verified purchase
Seems Great!
It’s hard to tell if a pill is working, but my stomach seems to need a probiotic. This one was reasonably priced and Target would bring it to my car!