ONE PILL A DAY. 24 HOURS. ZERO HEARTBURN.* With one pill a day, Prilosec OTC blocks acid production at the source so you don't get heartburn in the first place*THE FIRST AND ORIGINAL OVER-THE-COUNTER FREQUENT HEARTBURN MEDICINE. There's a reason 30 Million Americans± used Prilosec OTC to treat their frequent heartburn#1 Doctor, Gastroenterologist and Pharmacist recommended frequent heartburn treatment for 15 straight years^. May be HSA/ FSA eligible**TREATS FREQUENT HEARTBURN. There's no need to stash antacids everywhere for whenever heartburn might strike. With Prilosec OTC, you can take 1 pill a day for 24 hours of zero heartburn*BLOCKS ACID PRODUCTION AT ITS SOURCE. Proton pump inhibitors (PPIs) like Prilosec OTC reduce stomach acid production by shutting down many of the pumps in the stomach that produce acid