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Miconazole Vaginal Antifungal Cream - 1 day Treatment - 0.32oz - up&up™ - 2 of 4Miconazole Vaginal Antifungal Cream - 1 day Treatment - 0.32oz - up&up™ - 3 of 4Miconazole Vaginal Antifungal Cream - 1 day Treatment - 0.32oz - up&up™ - 4 of 4
Miconazole Vaginal Antifungal Cream - 1 day Treatment - 0.32oz - up&up™ - 1 of 4

Miconazole Vaginal Antifungal Cream - 1 day Treatment - 0.32oz - up&up™

$13.99 ($43.72/ounce)

In Stock

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At a glance

About this item

Highlights

  • Compare to Monistat 1 Combination Pack active ingredients.
  • Feminine care product cures most vaginal yeast infections.
  • Includes one softgel insert, one suppository applicator plus external cream.
  • Yeast infection treatment contains miconazole nitrate, an antifungal.
  • Yeast infection treatment for women helps to relieve uncomfortable symptoms.

Description

Compare to the active ingredients in Monistat 1 Combination Pack. Vaginal health is an important aspect of women’s overall health. When things get uncomfortable down there, you can find the relief you need with up&up 1-Day Treatment Miconazole 1, Miconazole Nitrate Vaginal Insert (1200 mg) and Miconazole Nitrate Vaginal Cream (2 Percent). This 1-day treatment plus external cream cures most vaginal yeast infections and relieves associated external itching and irritation. This feminine hygiene product includes 1 vaginal softgel insert, 1 comfortable flexible suppository applicator plus external cream for itch relief.
Suggested Age: 12 Years and Up
Product Warning: Not for children under the age of 12
Product Form: Cream
Primary Active Ingredient: Miconazole
Package Quantity: 1
Net weight: .32 Ounces
TCIN: 12980979
UPC: 370030622320
Item Number (DPCI): 245-03-0265
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

miconazole nitrate (1200 mg) (in vaginal insert), miconazole nitrate (2%) (external cream).

Purpose

Purpose: Vaginal Antifungal, Vaginal Antifungal.

Uses

Relieves external itching and irritation due to a vaginal yeast infection., Treats vaginal yeast infections.

Ask a doctor before use if

Ask a doctor before use if you have: vaginal itching and discomfort for the first time, lower abdominal, back or shoulder pain, fever, chills, nausea, vomiting, or foul-smelling vaginal discharge (you may have a more serious condition), vaginal yeast infections often (such as once a month or 3 in 6 months) (You could be pregnant or have a serious underlying medical cause for your symptoms, including diabetes or a weakened immune system), been exposed to the human immunodeficiency virus (HIV) that causes Aids.

Ask a doctor or pharmacist before use if

Ask a doctor or pharmacist before use if you are taking the prescription blood thinning medicine warfarin, because bleeding or bruising may occur.

Stop use and ask a doctor if

symptoms do not get better in 3days, symptoms last more than 7 days, you get a rash or hives, abdominal pain, fever, chills, nausea, vomiting, or foul-smelling vaginal discharge.

Pregnancy/breast-feeding warning

If pregnant or breast-feeding, ask a health professional before use.

For use

For vaginal use only

Keep out of reach

If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

Do not use

if you have never had a vaginal yeast infection diagnosed by a doctor.

When using

do not use tampons, douches, spermicides or other vaginal products (Condoms and diaphragms may be damaged and fail to prevent pregnancy or sexually transmitted diseases [STDs]), do not have vaginal intercourse, mild increase in vaginal burning, itching or irritation may occur, if you do not get complete relief ask a doctor before using another product.

Directions

Before using this product read the enclosed consumer information leaflet for complete directions and information. Do not flush.

Adults and Children 12 Years of Age and Older:

Vaginal Insert: with applicator place the vaginal insert into the vagina. Throw applicator away after use. External Cream: Squeeze a small amount of cream onto your fingertip. Apply the cream onto the itchy, irritated skin outside the vagina. Use 2 times daily for up to 7 days, as needed.

Children Under 12 Years of Age:

Ask a doctor.

Other information

Do not use if printed sealed pouch is torn, open or incompletely sealed. Do not use if seal over tube opening has been punctured or cannot be seen. Do not purchase if carton is open. Store at 68-77 degrees F (20-25 degrees C). This is a 1-dose treatment. Most women do not get complete relief of their symptoms in just 1 day. Most women get some improvement in 1 day and complete relief by 7 days.

Inactive ingredients

vaginal insert: fractionated coconut oil, gelatin, glycerin, lecithin, light mineral oil, purified water, titanium dioxide, white petrolatum. external cream: benzoic acid, butylated hydroxyanisole, glyceryl stearate, mineral oil, peglicol 5 oleate, pegoxol 7 stearate, purified water. soothe wipes feminine wipes ingredients: water, propylene glycol, aloe barbadensis leaf juice, tocopheryl acetate, peg-75 lanolin, disodium cocoamphodiacetate, polysorbate 20, fragrance, citric acid, disodium phosphate, disodium edta, 2-bromo-2-nitropropane-1, 3-diol, iodopropynyl butylcarbamate.

Question or comments?

888-547-7400

Ingredients:

active ingredients: miconazole nitrate (1200 mg) (in vaginal insert), miconazole nitrate (2%) (external cream). purpose: vaginal antifungal, vaginal antifungal inactive ingredients: vaginal insert: fractionated coconut oil, gelatin, glycerin, lecithin, light mineral oil, purified water, titanium dioxide, white petrolatum, external cream: benzoic acid, butylated hydroxyanisole, glyceryl stearate, mineral oil, peglicol 5 oleate, pegoxol 7 stearate, purified water.

Shipping details

Estimated ship dimensions: 7.09 inches length x 5.28 inches width x 1.18 inches height
Estimated ship weight: 0.08 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Additional product information and recommendations

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3.9 out of 5 stars with 729 reviews
quality: 2.75 out of 5
value: 2.84 out of 5
38% would recommend
188 recommendations
1 out of 5 stars
Thumbs down graphic, would not recommend
17 February, 2026

Burns and irritation

This product is horrible it burns and stings after one hour save your self some pain and look for alternatives
1 reply from the Product Manufacturer team - 1 month ago
We are sorry to hear about your experience with the Up & Up Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2133710. We look forward to addressing your concerns and hearing from you!
Yesica
2 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
4 February, 2026Verified purchase

INTENSE Burning and Itching! AVOID!

Worst product! This medicine made me burn and itch like CRAZY! (None prior to insertion) For like 2 days… not worth it!!!!
1 reply from the Product Manufacturer team - 2 months ago
We are sorry to hear about your experience with the Up & Up Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2128611. We look forward to addressing your concerns and hearing from you!
Surgama4
quality: 1 out of 5
value: 1 out of 5
2 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
30 January, 2026Verified purchase

DO NOT USE, MAY COME WITH LOTS OF PAIN

I would NOT recommend using this. Within about 2-3 hours, I was in so much pain with a horrendous burning sensation that it woke me up and I was so freaked out that I woke my mom up balling my eyes out. She said to sit in really cold water in the tub, which helped the outside but I had to use my shower head to rinse in between. It helped enough for me to sleep but it took a little over 24 hours for the burning sensation to go away. Worst 24 hours of my life and I had appendicitis.
1 reply from the Product Manufacturer team - 2 months ago
We are sorry to hear about your experience with the Miconazole Vaginal Antifungal Cream - 1 day Treatment - 0.32oz - up&up™ . We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 800-719-9260 or via email by going to www.perrigo.com/contact-us and reference case number 2127180. We look forward to addressing your concerns and hearing from you!
Anon
quality: 1 out of 5
value: 1 out of 5
2 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
15 January, 2026

DO NOT BUT

like the other women here. i woke up with intense itching burning feeling at 3 am to the point that i cried. so im writing this as i have an ice pack in between my legs. i took a benadryl pill too and seems like the feeling is going down but not away. on a scale 1-10 i would say the itching was at a solid 8.5. very intense to the point where im willing to do WHATEVER to get it to go away. i never been so upset to the point where i write a review especially that i had to hop on here while in pain to write it.
1 reply from the Product Manufacturer team - 3 months ago
We are sorry to hear about your experience with the Up & Up Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2121402. We look forward to addressing your concerns and hearing from you!
C
quality: 1 out of 5
value: 1 out of 5
3 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
5 January, 2026

I TRIED TO TOUGH IT OUT

Please read the non promotional reviews! The burning sensation started about 1 hr after applying and became unbearable within 3 hrs! Swelling, redness and intense burning to the point that I had to wash everything out. After washing the burning was manageable but please don’t risk it! I’ll be attempting to get my money back thanks to their brand satisfaction return policy.
1 reply from the Product Manufacturer team - 3 months ago
We are sorry to hear about your experience with the Up & Up Miconazole Vaginal Antifungal Cream. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2117830. We look forward to addressing your concerns and hearing from you!
Renturntosener
quality: 1 out of 5
value: 1 out of 5
4 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
20 December, 2025

(no review title)

This made me itch so badly that I ended up crying
1 reply from the Product Manufacturer team - 3 months ago
We are sorry to hear about your experience with the Up & Up Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2114095. We look forward to addressing your concerns and hearing from you!
Dee
quality: 1 out of 5
value: 1 out of 5
5 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
14 December, 2025

(no review title)

Terrible product, more burning and itching after use, and the applicator is very difficult to use. Total waste of my money.
1 reply from the Product Manufacturer team - 4 months ago
We are sorry to hear about your experience with the Up & Up Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2112247. We look forward to addressing your concerns and hearing from you!
TIMA
quality: 1 out of 5
value: 1 out of 5
4 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
24 August, 2025

Burns

Would put zero stars if that were an option. Insertion is easy (I’m well-versed in tampons and period cups and so on). Use is easy. But after two hours of laying down I went to pee and after, I started burning like crazy. I wasn’t experiencing burning sensation with the infection before inserting (discomfort and swelling and itching, yes.) currently on fire. Used baby wipes to really clean and the burning continued. Had to take an immediate bath and the pain had not yet subsided. Feels absolutely terrible. This product is not for everyone. 😬
1 reply from the Product Manufacturer team - 7 months ago
We are sorry to hear about your experience with the Miconazole Vaginal Antifungal Cream product. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 1-800-719-9260 or via email by going to www.perrigo.com/contact-us and reference case number 2076364. We look forward to addressing your concerns and hearing from you!
Heather
quality: 1 out of 5
value: 1 out of 5
6 guests found this review helpful. Did you?
2 out of 5 stars
28 July, 2025Verified purchase

Was it worth that pain?

I wished I would have read the reviews first. 😭 I was flopping around like a fish out of water for an hour or so while the magic egg performed its exorcism. I did give it two stars because it didn’t work. Was it worth that pain? I’m not sure. I’d attempt other alternatives before you go for this beast.
1 reply from the Product Manufacturer team - 8 months ago
We are sorry to hear about your experience with the Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2067520. We look forward to addressing your concerns and hearing from you!
CL
12 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
3 July, 2025Verified purchase

everyone's different!

my first time ever leaving a product review just to give hope to anyone scared off by others! i was worried after reading the reviews but didn’t experience any pain and found the applicator perfectly useful! cleared up my mild infection quickly and easily
anonymous
quality: 5 out of 5
value: 5 out of 5
6 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
3 July, 2025

Terrible Product

Burns so bad! Use other brands of creams or go to urgent care/Doctor for a pill! I had such a hard time following through with dose 3 because 2 was so uncomfortable. 3 was worse. Not worth it!!!
1 reply from the Product Manufacturer team - 9 months ago
We are sorry to hear about your experience with the Up & Up Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2060575. We look forward to addressing your concerns and hearing from you!
K
quality: 1 out of 5
value: 1 out of 5
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
28 June, 2025Verified purchase

Didnt Burn

I had no issues with this at all. Previously another brand burned for me, so I was nervous initially. I truly think the pain you feel depends on how bad of a YI you have. Mine was super minor and this pretty much took care of it.
Nj
quality: 5 out of 5
value: 3 out of 5
4 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
28 June, 2025

Not worth the stronger dose

Four hours later and I am up itchy and burning like the other comments say. I had to take benedryl, shower off the external cream and now sitting with ice pack between my legs. Get the longer dosed version not worth it
1 reply from the Product Manufacturer team - 9 months ago
We are sorry to hear about your experience with the Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2058281. We look forward to addressing your concerns and hearing from you!
Savcog
quality: 1 out of 5
value: 1 out of 5
2 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
27 June, 2025Verified purchase

Beware!

Do Not Buy!!! Extreme burning and discomfort!!
1 reply from the Product Manufacturer team - 9 months ago
We are sorry to hear about your experience with the Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2058278. We look forward to addressing your concerns and hearing from you!
VaneVG
quality: 1 out of 5
value: 1 out of 5
1 guest found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
27 June, 2025Verified purchase

AVIOD!!!!

Intense burning, never will I ever use again!
1 reply from the Product Manufacturer team - 9 months ago
We are sorry to hear about your experience with the Miconazole. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2057938. We look forward to addressing your concerns and hearing from you!
Notahappycamper
quality: 1 out of 5
value: 1 out of 5
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
25 June, 2025Verified purchase

Easy to use

I received product reimbursement in exchange for my honest review. This is a great product. I was pleased with how small the soft gel insert was. I also appreciated that a small tube of external cream was included. It was easy to use and effective.
Julie
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
4 out of 5 stars
Thumbs up graphic, would recommend
25 June, 2025

Works as described

I received product reimbursement in exchange for my honest review. This product worked as described. It was an easy one dose and came with everything needed. I appreciate the maximum dosage option as well. This is a good alternative to the "other" brand that sells for much more.
Lmk
quality: 4 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
21 June, 2025Verified purchase

Good product

I received product reimbursement in exchange for my honest review. This product really works. It comes with an insert, an applicator and also a cream. The applicator is easy to use and the instructions are easy to follow. The cream is good to alleviate the itchiness immediately. It is also a way better deal than other brands. I do recommend this product.
Caroline
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
4 out of 5 stars
Thumbs up graphic, would recommend
21 June, 2025Verified purchase

Good product

I received product reimbursement in exchange for my honest review. This product worked as it should. I did not experience any burning sensations or any other issues with it. It is easy to use and does the job. It cleared things up quickly.
KARA711
quality: 4 out of 5
value: 4 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
16 June, 2025

Quality product

Great alternative to the name brand.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

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