Spiro Compounds - by Ramon Rios Torres (Hardcover)

About the Book

"Spirocycles are important structural elements due their unique properties. The major characteristics of spiro scaffolds are thire structural complexity and rigidity, favorable features in medicinal chemistry optimization programs against selected targets. The inherent challenges and the utility in drug discovery of these compounds have attracted the attention of several research groups that made huge steps in the development of new methodologies for their synthesis"--

Book Synopsis

SPIRO COMPOUNDS

A comprehensive treatment of the latest research in, and applications of, spiro compounds

Spiro Compounds: Synthesis and Applications combines discussions of the latest advances in spiro compound research with the most cutting-edge, real-world applications of that knowledge. This book provides in-depth coverage of the history, significance, properties, synthetic methods, and applications of spiro compounds. As interest in spiro compounds grows due to their unique conformational features and their structural implications on biological systems, Spiro Compounds delivers fulsome treatments of advances in spiro compound synthesis (including stereoselective synthesis) methodologies.

With a special focus on the mechanisms of the reactions that lead to the synthesis of spiro compounds, chapters in the book cover topics such as:

• The history, significance, and unique properties of spiro compounds
• The most important methodologies for their synthesis
• The applications of spiro compounds in organic chemistry, biology, drug discovery
• The most important syntheses of natural products bearing a spiro ring

Perfect for academic and industrial chemists, this comprehensive discussion of spirocycles is an indispensable resource for those practicing in the field.

From the Back Cover

A comprehensive treatment of the latest research in, and applications of, spiro compounds

Spiro Compounds: Synthesis and Applications combines discussions of the latest advances in spiro compound research with the most cutting-edge, real-world applications of that knowledge. This book provides in-depth coverage of the history, significance, properties, synthetic methods, and applications of spiro compounds. As interest in spiro compounds grows due to their unique conformational features and their structural implications on biological systems, Spiro Compounds delivers fulsome treatments of advances in spiro compound synthesis (including stereoselective synthesis) methodologies.

With a special focus on the mechanisms of the reactions that lead to the synthesis of spiro compounds, chapters in the book cover topics such as:

• The history, significance, and unique properties of spiro compounds
• The most important methodologies for their synthesis
• The applications of spiro compounds in organic chemistry, biology, drug discovery
• The most important syntheses of natural products bearing a spiro ring

Perfect for academic and industrial chemists, this comprehensive discussion of spirocycles is an indispensable resource for those practicing in the field.

About the Author

Ramon Rios Torres, PhD is Associate Professor in Organic Chemistry at the University of Southampton. He is the author of more than 130 papers, 18 chapters in chemical books, and a patent. Dr. Rios has edited two books with Wiley: Stereoselective Organocatalysis: Bond Formation Methodologies and Activation Modes and The Pauson-Khand Reaction: Scope, Variations and Applications.