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Spray Calamine Lotion - 4.1oz - up&up™
Only at  target 
$4.59
In Stock
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At a glance
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About this item
Highlights
- Packaging may vary. Same trusted quality
- Compare to Caladryl active ingredients
- No-rub calamine spray is a mess-free way to administer relief
- For use on dry, sore and itchy skin affected by rashes or bug bites
- Topical analgesic reduces pain while protecting skin from further irritation
Description
Everyone knows calamine lotion tends to be a thick, messy cream that's almost not worth the effort. Eliminate the sticky, messy application with Spray Calamine Lotion from up&up™ and you'll get instant relief from itchy, rashy skin with half the time and effort. A mist administers the lotion evenly across the affected areas, to start working everywhere at once. If you've had run-ins with mosquitoes or poisonous plants, this is the spray to use to get back out there faster and with more comfort.
We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.
Satisfaction guaranteed – Love it or your money back.
We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.
Satisfaction guaranteed – Love it or your money back.
Product Warning: Keep out of reach of children, flammable, not for children under the age of two, eye irritant
Product Form: Spray
Net weight: 4.1 Ounces
TCIN: 52948985
UPC: 034197015370
Item Number (DPCI): 245-07-0473
Origin: Assem USA w/foreign/dom. parts
Healthcare Disclaimer: 
Content on this site is for reference purposes only.  Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers.  On occasion, manufacturers may improve or change their product formulas and update their labels.  We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions.  If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.
Active ingredients
calamine' '8.0% pramoxine hcl' '1.0%
Purpose
SKIN PROTECTANT EXTERNAL ANALGESICUses
TEMPORARILY RELIEVES PAIN AND ITCHING ASSOCIATED WITH: INSECT BITES, RASHES, MINOR SKIN IRRITATIONS, MINOR CUTS, DRIES THE OOZING AND WEEPING OF POISON IVY, POISON OAK AND POISON SUMACOther information
STORE BETWEEN 20° TO 25°C (68° TO 77°F)Inactive ingredients
benzyl alcohol, camphor, disteardimonium hectorite, fragrance, hydrated silica, isobutane, oleyl alcohol, sd alcohol 40-b, sorbitan trioleate' '
Shipping details
Estimated ship dimensions: 12.95 inches length x 12.91 inches width x 10.9 inches height
Estimated ship weight: 0.37 pounds
We regret that this item cannot be shipped to PO Boxes.
This item cannot be shipped to the following locations: American Samoa (see also separate entry under AS), Guam (see also separate entry under GU), Northern Mariana Islands, Puerto Rico (see also separate entry under PR), United States Minor Outlying Islands, Virgin Islands, U.S., APO/FPO, Alaska, Hawaii
Return details
This item must be returned to any Target store.
This item must be returned within 365 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
Q: Does this work for dry skin that is itchy?
submitted by Stacyk - 9 months ago
- A: “Hello Stacyk -We thank you for your interest in the Spray Calamine Lotion - 4.1oz - up&up™. This lotion is designed to provide relief for dry, sore, and itchy skin caused by rashes or insect bites, offering immediate comfort from discomfort. We are confident that you will find it beneficial. – Chris” submitted byChris - 9 months agoTarget staff support
Q: Is this spray clear in color?
submitted by aboc - 2 years ago
- A: Great question, the Calamine Spray is a Pink Powder Spray. Hope this helps! Thank you. submitted byPremier Brands of America - 1 year agoBrand expert
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Related Categories
4.4 out of 5 stars with 894 reviews
quality: 3.84 out of 5
value: 3.84 out of 5
67% would recommend
114 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
30 September, 2025Verified purchase
IT WORKS
I originally bought this to ease the itch from a shingles episode. It was an absolute Godsend for this purpose. Later on during the summer, I got eaten alive by mosquitos as usual and was fed up with the relentless itching that kept me up through the night. In desperation, I googled remedies for mosquito bite itch and lo and behold, calamine was listed. I mean, duh, right? I should have known, but anyway I grabbed this little bottle off the shelf and holy instant relief! I can’t believe I’ve gone my whole life without figuring this out. Anywho, it works, and works well. The spray is the most convenient and mess-free option. I’ll be keeping a bottle in the cabinet at all times!
1 out of 5 stars
Thumbs down graphic, would not recommend
10 August, 2025Verified purchase
Horrible smelling
Horrible smelling didn’t help
5 out of 5 stars
Thumbs up graphic, would recommend
31 July, 2025Verified purchase
Mess free
We love the mess free application and relief from itchy bug bites.
1 out of 5 stars
Thumbs down graphic, would not recommend
27 July, 2025Verified purchase
Stinks
Works fine but smell gets on all the clothes, bedding, carpet, and couch and reeks. It took me weeks to find the culprit of the stench of my 11 year old and 8 year olds bedroom. I thought it was puberty but it was the stench of this spray they constantly put on all their summer mosquito bites. I washed every single piece of clothing in their room, shampooed the carpets and deodorized their mattresses and sun baked them. The smell went away for about a week when the mosquitos hit again. And once they did, the stench came back. Threw away the pink stuff and stench is gone. Finally.
5 out of 5 stars
Thumbs up graphic, would recommend
27 July, 2025Verified purchase
Fantastic and really works.
Really works, stopped the itching immediately. Easy to use, no weird color left on skin.
1 out of 5 stars
Thumbs down graphic, would not recommend
20 July, 2025Verified purchase
Be aware fragrance added!
The smell was horrendous and it gave me a rash wherever the spray was
5 out of 5 stars
Thumbs up graphic, would recommend
17 July, 2025
Miracle in a can!
Works great! A lot of people complain about a scent but the only thing I smelled was the aerosol? It quickly went away once I stopped spraying.
2 out of 5 stars
16 June, 2025Verified purchase
Contains fragrance
Beware this product has a very heavy fragrance. I am unsure why a company would add fragrance to a product that is meant to sooth already irritated skin.
5 out of 5 stars
Thumbs up graphic, would recommend
15 June, 2025Verified purchase
Great aruff
Really helped when I had a massive allergic reaction and was covered in hives. Wish I’d known about this sooner!
5 out of 5 stars
Thumbs up graphic, would recommend
7 December, 2024Verified purchase
Does the job
Helped with my daughters bug bites
5 out of 5 stars
Thumbs up graphic, would recommend
30 November, 2024Verified purchase
Stops itching immediately!
I had poison ivy, and couldn’t sleep at night until finding this product! It is absolutely the only thing that helped the itching! It numbs the area, and is absolutely a life saver!
5 out of 5 stars
Thumbs up graphic, would recommend
16 November, 2024Verified purchase
Great product
This is a favorite in my family!! We go through at least 2 a year. My family tends to get poison ivy/sumac every year and this helps us out so much. It’s easy to use and isn’t runny like the liquid version.
3 out of 5 stars
Thumbs down graphic, would not recommend
12 November, 2024
Need a fragrance free option
The fragrance is awful. If I weren’t so itchy, I’d wash it off immediately. It did give immediate relief to my plant induced rash, but ick. The smell is so terrible.
5 out of 5 stars
Thumbs up graphic, would recommend
10 November, 2024Verified purchase
Good itch spray!
Easy spray to use to help ease the itch! Kids approve! Not messy, and dries quick.
5 out of 5 stars
Thumbs up graphic, would recommend
7 October, 2024Verified purchase
Great!
Bought this to use on my sons mosquito bites. He said it helped ease the itchiness and the cooling scentation felt nice. Will definately keep this in our medicince cabinet from now on.
3 out of 5 stars
Thumbs down graphic, would not recommend
6 October, 2024Verified purchase
Meh
The liquid lotion is much better
1 out of 5 stars
Thumbs down graphic, would not recommend
3 October, 2024Verified purchase
DO NOT USE IF YOU HAVE ASTHMA!!!
Ineffective Pink Perfume. I should have read the label before use as I sprayed this all over mosquito bites and then the cloud of perfume activated my asthma and I had to use my inhaler several times before i could breathe right again. I washed it off immediately but the smell lingered in my room for hours. Also made itching worse. Would give ZERO stars if I could. Disgusting. And got a rash allergic reaction from it. Could not be worse.
4 out of 5 stars
Thumbs up graphic, would recommend
2 October, 2024Verified purchase
Convenient but beware of burn!
Love the convenience and no mess of the spray but this product burrrnnnssss. I had a nasty case of poison ivy and the burn was fine for me as an adult but my kids absolutely cannot use this stuff as it makes their bug bites and other rashes burn for a good 10 seconds. Wouldn’t recommend for children which is a bummer since the spray is so useful for application on kids.
2 out of 5 stars
Thumbs down graphic, would not recommend
7 September, 2024Verified purchase
Buy the brand name
Didn’t last long. Wasn’t as full as brand name. Possibly the nozzle is defective.
1 out of 5 stars
Thumbs down graphic, would not recommend
2 September, 2024
Gross (pink spray)
Goes on pink and stays pink and gets on everything. Was hoping it was a clear spray but nope pink. Don’t use unless you want to ruin clothing and furniture your skin comes into contact with.