Daytime Cold & Flu Multi-symptom Relief Liquid - 12 fl oz - up&up™: Alcohol-Free, Acetaminophen 325mg, Original Flavor
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$5.49 ($0.46/fluid ounce)
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Highly rated
$1.59 - $7.99
$15 Target GiftCard with $50 household items purchase
4.7 out of 5 stars with 10631 ratings
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Guests are saying
The product has received mixed feedback from guests, primarily due to a recent formula change that has altered its taste and effectiveness. While many guests appreciate its affordability and effectiveness compared to name brands, the new flavor has disappointed numerous long-time users. Some guests have reported adverse reactions, while others still find it a reliable option for cold and flu relief. Overall, it remains a popular choice for those seeking value in their medicine.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.6 out of 5 stars with 1076 reviews
quality: 3.5 out of 5
value: 3.75 out of 5
60% would recommend
71 recommendations
1 out of 5 stars
Thumbs down graphic, would not recommend
23 March, 2026Verified purchase
Tastes AWFUL!
Whatever they changed definitely was not for the better. It tastes horrendous and does not work as well. Returned for a refund. Compared inactive ingredients with my old bottle and it it not the same.
4 out of 5 stars
Thumbs up graphic, would recommend
17 March, 2026Verified purchase
Cough B Gone
Well I got sleep last night, yippie!! Yes, this actually worked :)
1 out of 5 stars
11 March, 2026
Not very effective
This one tastes disgusting now. It also seems to not be very effective anymore. Within 2 hours of taking I feel miserable again.something must have drastically changed
3 out of 5 stars
7 March, 2026Verified purchase
Pass
Not as good as DayQuil at relieving my symptoms. In fact, at times I felt worse after drinking this.
2 out of 5 stars
20 February, 2026Verified purchase
Not the best
Somehow this tastes worse than actual DayQuil. Like it tastes like some sort of paint thinner or polyurethane. It does the job okay but not sure if the taste is worth it when other stores’ generic DayQuil doesn’t taste quite as awful.
1 out of 5 stars
Thumbs down graphic, would not recommend
2 February, 2026Verified purchase
Horrible taste.
Horrible taste. I think something is wrong with this!
1 out of 5 stars
Thumbs down graphic, would not recommend
25 January, 2026
Terrible, made me really sick in the stomach
Got this for cold symptoms as I have used DayQuil dupes previously with no issue. This one is a no, after 10 minutes my stomach was an absolute wreck. Thought maybe it was a coincidence and tried a different time, same thing. So, don't try, you'll still feel all your cold symptoms with the added bonus of gastrointestinal issues.
1 out of 5 stars
21 January, 2026Verified purchase
(no review title)
This has been recently updated and the new version is not as thick and has a bad taste. I’ve always bought the UP&UP brand but since the bottle and formula was changed, I’ll look for other options
5 out of 5 stars
Thumbs up graphic, would recommend
3 January, 2026Verified purchase
good for the price
my go to!
1 out of 5 stars
Thumbs down graphic, would not recommend
26 December, 2025Verified purchase
Maybe not for kids.
This might be okay for adults, but my son doesn’t like its taste and smell. He didn’t feel good when he took it.
1 out of 5 stars
Thumbs down graphic, would not recommend
8 November, 2025
Dont buy, you wont be able to get past the taste
This WAS my go to cough medicine but holy crap the new formula is NOT palatable. It tastes awful. Disappointed that I’ll have to find a new cough syrup.
1 out of 5 stars
Thumbs down graphic, would not recommend
28 October, 2025
(no review title)
Have purchased this in the past. I get cold medicine can’t taste good but the new formula tastes terrible - cannot even stomach taking a full cap. Worst thing I’ve ever tasted (and I am not exaggerating). I’m willing to pay double for brand name just to forget about this experience.
5 out of 5 stars
Thumbs up graphic, would recommend
17 October, 2025Verified purchase
Best little helper in a bottle.
This is a great dupe for the name brand Day Quil. Everyone I work with has children, and all surfaces in the workplace are shared (kitchen, desks, computers, etc) so cold and flu viruses tend to run rampant from the start of back to school season through mid spring. Unfortunately I can't always get through the season without getting a gnarly cold. Fortunately, this stuff helps me get through a shift as a functional human being. It also helps with my horrendous hayfever symptoms after cold/flu season is over, which is an absolute godsend. And the taste isn't half bad!
3 out of 5 stars
Thumbs down graphic, would not recommend
4 October, 2025Verified purchase
TASTES TERRIBLE
The low price is the only reason pro. The taste is AWFUL. It’s absolutely terrible. So bad that I will pay extra for name brand next time so I don’t have to taste this again.
1 out of 5 stars
Thumbs down graphic, would not recommend
9 September, 2025Verified purchase
New formula taste is bad.
The new taste is awful.
2 out of 5 stars
Thumbs down graphic, would not recommend
15 June, 2025Verified purchase
Too watery
Not the same as DayQuil, it’s too watery and doesn’t work as well. Skip this one and buy the real thing.
1 out of 5 stars
Thumbs down graphic, would not recommend
1 May, 2025
New formula, can't recommend anymore
Yes, it’s true. The new taste formula is awful. I find myself struggling to drink the medicine, unlike with the old taste formula. And yes, “crystals” appear at the bottom of the formula. I noticed a lot of them with crystals on the shelf with a July 2026 expiration date. The June 2026 expiration date bottles don’t have crystals. I literally checked every bottle on the shelf in-store. 5-stars will only return if the old formula returns. Buy DayQuil or another generic store brand due to these issues.
1 out of 5 stars
Thumbs down graphic, would not recommend
20 April, 2025Verified purchase
Buy anything else.
I think I’d rather drink untreated sewage than try this disgusting “medicine” again. Honestly I don’t know what flavor they were trying to make but it’s awful.
3 out of 5 stars
Thumbs down graphic, would not recommend
31 March, 2025Verified purchase
Noooo
Doesn’t really work. Taste just as bad but doesn’t work.
1 out of 5 stars
Thumbs down graphic, would not recommend
20 March, 2025
New formula
This new formula is so hard to swallow due to the disgusting strong, taste. It isn’t as effective as the old formula was, either.