Original 12hr Nasal Spray - Oxymetazoline Hydrochloride 0.05% - 1 fl oz - up&up™
$3.49 ($3.49/fluid ounce)
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- $4.59($9.18/fluid ounce)4.5 out of 5 stars with 948 ratings
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- $4.59($9.18/fluid ounce)4.5 out of 5 stars with 948 ratings
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Guests are saying
This nasal spray offers effective relief for allergy sufferers, providing a cool sensation and quick results. Many guests appreciate its affordability and effectiveness compared to name brands. However, the lack of a proper spray system has led to usability concerns, as some guests found it difficult to dispense the product correctly. Overall, it serves well for those seeking immediate relief from nasal congestion during allergy season.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.2 out of 5 stars with 24 reviews
effectiveness: 2.33 out of 5
quality: 3 out of 5
value: 3 out of 5
80% would recommend
10 recommendations
1 out of 5 stars
Thumbs down graphic, would not recommend
20 February, 2026
(no review title)
While I was happy to save money over the name brand, the lack of a spray system makes this product basically unusable. You don’t know that it doesn’t have a spray system until it’s open so then you are stuck with a product you can’t use yet can’t return. Don’t waste your money.
1 reply from the Product Manufacturer team - 4 months ago
We are sorry to hear about your experience with the Up & Up 12hr Nasal Spray. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2134660. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
Thumbs down graphic, would not recommend
5 January, 2026Verified purchase
(no review title)
Unlike the brand oxymetazoline spray bottle, this does not have an adequate spray system. You basically have to squeeze the bottle to produce a spray, sometimes you will get just air. How can you tell if it’s just air or medicine when it’s literally in your nostril? Horrible delivery system on this product. Would definitely NOT recommend.
1 reply from the Product Manufacturer team - 5 months ago
We are sorry to hear about your experience with the Up & Up Original 12hr Nasal Spray. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2117832. We look forward to addressing your concerns and hearing from you!
2 out of 5 stars
18 December, 2025Verified purchase
(no review title)
i dont understand how to use the bottle since it doesnt have a pump but it doesnt say that on the outside. the price was good but now i cant use it sooo....
1 reply from the Product Manufacturer team - 6 months ago
We are sorry to hear about your experience with the Up & Up Nasal Spray. To use, push firmly down on the cap and turn counter clockwise. To spray, squeeze the bottle quickly and firmly. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2114079. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
7 September, 2025Verified purchase
It works
It works just as well as the name brand
4 out of 5 stars
Thumbs up graphic, would recommend
20 April, 2025
Congestion Relief
My allergies have gotten worse as I get older. I definitely need some relief each spring and feel like nasal sprays give me the most bang for my buck. This Nasal Spray by up&up helps eith congestion, BUT it says do not use for more than 3 days. I will give it a try for my next cold, and hope it brings relief but for allergy suffering I will be using a different product that can be used for the season.
5 out of 5 stars
Thumbs up graphic, would recommend
17 April, 2025
Works fast and helps a lot
I got this Original 12hr Nasal Spray - Oxymetazoline HCl 0.05% - 1 fl oz - up&up for free but the opinions here are based on my own experiences. This actually worked really well. I have nasal issues from pet and seasonal allergies and sometimes I need to use nasal drops. These work just as good or better than other brands. I usually do one squirt in each nostril. I know not to sniff right away but I tilt my head back and let the nasal spray work in the nostril. There is a slight drainage down the back of the throat if you squirt too much but it's not bad. I had no issies and it tends to start working right away and lasts a long time. It also feels really cool in your nose. I really only use once a day if needed at all. Definitely recommend.
5 out of 5 stars
Thumbs up graphic, would recommend
11 April, 2025
Immediate relief to seasonal allergies
I started using this nasal spray a week ago when allergy season kicked off in my hometown. It was different than using an allergy pill because I had more immediate results and I didn't experience the fogginess of taking a pill.
5 out of 5 stars
Thumbs up graphic, would recommend
9 April, 2025
Great nasal spray
I received this product for free from Hey Bullseye in exchange for an honest review. I've used other nasal spray before and never liked how they felt. This product was easier to use. You dont feel the stream going up into your nasal passages.
4 out of 5 stars
Thumbs up graphic, would recommend
8 April, 2025
Maximum Relief
Allergy season always has me in a choke hold, especially living in the south. Our allergy season lasts long.. My sinuses are often a major struggle and disruptive. There's so mamy options out there but many are sub par, for multi symptoms or have drowsiness or other issues I cant deal with. This nasal spray option is powerful and effective, a couple sprays and I can breath again Real fast relief. Affordable as well. I definitely recommend this, it works.
5 out of 5 stars
Thumbs up graphic, would recommend
7 April, 2025
Works well
Every spring I experience mild allergy symptoms. This nasal spray has helped relieve a slightly runny nose for a few days. I didn’t experience any major symptoms, mostly just a super dry nose. I only used one puff per nose each time. The spray top works efficient. It’s different than the dropper looking top I’ve seen with similar products (see photo). I recommend upon first use, doing a few test sprays to make sure you get the most out of your nose spray. I did not do this the first time and wasn’t sure how much medicine I actually received.
5 out of 5 stars
Thumbs up graphic, would recommend
2 April, 2025
Big help comes in little packages!
I always have a nasal spray on hand. With the weather and allergies in the south, my kids get dryness so easily. Sometimes it causes them nosebleeds. To prevent this, I use nasal spray to keep their nostrils moist and they're better.